Gene detail

Detailed information of evm.model.Ap11.926 in Astrangia poculata

Genomic Location: Ap11:10239025...10241886
NR annotation: XP_020623134.1, protein toll-like [Orbicella faveolata]
Species Astrangia poculata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap11.926

atgtcatcgttcttcgaaacagataaaggaatagtcccagtgcaagccgtaaaatgtgcgttaaaaagcaacaagataaatgaccgatgtacagtggatattggtgtgattttaaaaacactaacagccagtcaagatgtcgtgttatattttgcacccatgtgtctcactccgatggaaattgttttcaacaattctttaaacgctacaaagaaaaacgctatatcttacctgcaaattaaggggcaatgtagcgtttcagtcgatgatatttctcactggggaaacgctacagactttcgagtcttttacgtactggaaaacgcgactttacttgaaggaaataattcactgggaaataactctcttcaggcattacaaaatgttggttctgttttaattgacaaatctaaaccgcgaaacattcccagcatgtttagtaaatacgtctggtccagaatggctgaggtgggattttccaacttacaacttacgacgatacctgcagagtttaataccacgatgccgcaactgcaatcgcttgagcttgcaaacaataagcttacaaagccaccatcgtttccatggtgtaacaccactctccaactgccaagaggattacaaagaactccaaccggaaatcatcattaccaattcggtactaacgtgcatccgaagatttaccgacgatttttcgatctgtcgtacaacaagatcgaagatttatcgaagcacgaatttcgaggacttctcaataaactgactctgcagggaaacggtttgaaagtcattggaccaacgtgttttcgcaatttgacgggaatacatgtgattgacctcagcaagaacaaattgaatgatttaccatcagagctgtttcaaggactcgatagtttgctcgaattacgacttgatcacaacaacatttcggtaatacgtaaagaactcttcaaatctgtgacgcagattgaacgaattgacttgaatggcaacaaactgagctatattccaaaagaattgttcagcttgttgaaaaatatcaaagttctgcatttagaagataaccaaatcacgcgagtggatgaaaaagctttccccatagattcaagttccctggaaaaaatttacctccaaaacaacaatataagtcgaattccaacctcactattactgcaacgaagcgccacagaaaccgacttgtcctttaatcagttgacttttcaagactttaacaggttgttacaagaattagattatgatgcatttatgtttcagcatcgtgaaactgcaagctcccctcaagtaagaatgcaagaaagtttaaagtacatcagtttcgctaacaacaagttcacgacgattaacatcgaggcattcaacaaaaccgaggaaattaagttcgagtatcttctacgggtttacaaaatcgacatgacggggaatccccttatgtgtgactgcaagattttattcttgactcgctggctacgagctttggtgcataaggtgacgcgcattcgaaaagaacagtttcaaacttggaaatgcgccgctccgagtgaactcaaaggtaaatcgattttatccgtggatgaagatcaatttcaatgccagagaaatcttgaaaactgccccagcggatgtttgtgttttgtgcgtgctttagacggaactgtcgtcatcgattgtaaaggaagaaacctaaccgcagtgcctcccaaagttccatgcggtcgcatagagctgaaattacaagacaacgacatccgggagattccaccctatccttatatggaaaatgtgacggcgctgtatttgacacaaaacaagattcaagtattaaacgactctacagtgcaaaaatttacacgaattaaaattctgtttatcgattccaataaactgaccgatttacccaggaatatcgaaaaggtaaactttacaactctggtattacaccacaatttctttaaatgcgactgcaaaacaaaatggatgaaaaactggttacggagaaaaaaaagtcaaatactgaacattggaaacgttctttgcaactctgagggaagtgcgcaaggaaaatcaatttacactctgccagatgacgagtttgtttgtaaacagaatgtagaagacaagtctccacaatctataacgaaggataagactttcagaataatcgccctgactcttggaagctcgctggttttgactatcatcgctttcatcctggtttacaagtttcgtggagaagtaaaggtcttcatgtacacccatttcaattggcacccatttgaccgcatagatgactcggatccaagcaagacatacgacgcgtttgtatcgttcagcggtaacgattaccaatgggttgtgaacatgttgcaagagcgactcgaaaatcacgaccttccttacaaactatgcattcatcaacgtgactttctagtgggcgcaccaatccaggaaaacattctgaacagcgtcgaccaaagtaaacgcatgctcatggtgctatctcgggactttttaaggagcgagtggtgcctgctggagtttcgcgccgcgcatcgtaaggtgttagaggaacgcatgaattatctgataattattctgtttgatgacgtcaacatggatgagcttgatgacgaaatgaagctgtacatgcgtactaacacttatcccagtgtcagtaacaagtggtttggggagaagttgtattacgcgatgccgcaaagtactgtggcagagtttagagcgagacatctctcaagcacttcctcgaatgctggtttagaatattcaaccgagacagtgcacaagaatggcgcatacctaaaagaaactgttattttagagtga

Transcript

evm.model.Ap11.926

ATGTCATCGTTCTTCGAAACAGATAAAGGAATAGTCCCAGTGCAAGCCGTAAAATGTGCGTTAAAAAGCAACAAGATAAATGACCGATGTACAGTGGATATTGGTGTGATTTTAAAAACACTAACAGCCAGTCAAGATGTCGTGTTATATTTTGCACCCATGTGTCTCACTCCGATGGAAATTGTTTTCAACAATTCTTTAAACGCTACAAAGAAAAACGCTATATCTTACCTGCAAATTAAGGGGCAATGTAGCGTTTCAGTCGATGATATTTCTCACTGGGGAAACGCTACAGACTTTCGAGTCTTTTACGTACTGGAAAACGCGACTTTACTTGAAGGAAATAATTCACTGGGAAATAACTCTCTTCAGGCATTACAAAATGTTGGTTCTGTTTTAATTGACAAATCTAAACCGCGAAACATTCCCAGCATGTTTAGTAAATACGTCTGGTCCAGAATGGCTGAGGTGGGATTTTCCAACTTACAACTTACGACGATACCTGCAGAGTTTAATACCACGATGCCGCAACTGCAATCGCTTGAGCTTGCAAACAATAAGCTTACAAAGCCACCATCGTTTCCATGGTGTAACACCACTCTCCAACTGCCAAGAGGATTACAAAGAACTCCAACCGGAAATCATCATTACCAATTCGGTACTAACGTGCATCCGAAGATTTACCGACGATTTTTCGATCTGTCGTACAACAAGATCGAAGATTTATCGAAGCACGAATTTCGAGGACTTCTCAATAAACTGACTCTGCAGGGAAACGGTTTGAAAGTCATTGGACCAACGTGTTTTCGCAATTTGACGGGAATACATGTGATTGACCTCAGCAAGAACAAATTGAATGATTTACCATCAGAGCTGTTTCAAGGACTCGATAGTTTGCTCGAATTACGACTTGATCACAACAACATTTCGGTAATACGTAAAGAACTCTTCAAATCTGTGACGCAGATTGAACGAATTGACTTGAATGGCAACAAACTGAGCTATATTCCAAAAGAATTGTTCAGCTTGTTGAAAAATATCAAAGTTCTGCATTTAGAAGATAACCAAATCACGCGAGTGGATGAAAAAGCTTTCCCCATAGATTCAAGTTCCCTGGAAAAAATTTACCTCCAAAACAACAATATAAGTCGAATTCCAACCTCACTATTACTGCAACGAAGCGCCACAGAAACCGACTTGTCCTTTAATCAGTTGACTTTTCAAGACTTTAACAGGTTGTTACAAGAATTAGATTATGATGCATTTATGTTTCAGCATCGTGAAACTGCAAGCTCCCCTCAAGTAAGAATGCAAGAAAGTTTAAAGTACATCAGTTTCGCTAACAACAAGTTCACGACGATTAACATCGAGGCATTCAACAAAACCGAGGAAATTAAGTTCGAGTATCTTCTACGGGTTTACAAAATCGACATGACGGGGAATCCCCTTATGTGTGACTGCAAGATTTTATTCTTGACTCGCTGGCTACGAGCTTTGGTGCATAAGGTGACGCGCATTCGAAAAGAACAGTTTCAAACTTGGAAATGCGCCGCTCCGAGTGAACTCAAAGGTAAATCGATTTTATCCGTGGATGAAGATCAATTTCAATGCCAGAGAAATCTTGAAAACTGCCCCAGCGGATGTTTGTGTTTTGTGCGTGCTTTAGACGGAACTGTCGTCATCGATTGTAAAGGAAGAAACCTAACCGCAGTGCCTCCCAAAGTTCCATGCGGTCGCATAGAGCTGAAATTACAAGACAACGACATCCGGGAGATTCCACCCTATCCTTATATGGAAAATGTGACGGCGCTGTATTTGACACAAAACAAGATTCAAGTATTAAACGACTCTACAGTGCAAAAATTTACACGAATTAAAATTCTGTTTATCGATTCCAATAAACTGACCGATTTACCCAGGAATATCGAAAAGGTAAACTTTACAACTCTGGTATTACACCACAATTTCTTTAAATGCGACTGCAAAACAAAATGGATGAAAAACTGGTTACGGAGAAAAAAAAGTCAAATACTGAACATTGGAAACGTTCTTTGCAACTCTGAGGGAAGTGCGCAAGGAAAATCAATTTACACTCTGCCAGATGACGAGTTTGTTTGTAAACAGAATGTAGAAGACAAGTCTCCACAATCTATAACGAAGGATAAGACTTTCAGAATAATCGCCCTGACTCTTGGAAGCTCGCTGGTTTTGACTATCATCGCTTTCATCCTGGTTTACAAGTTTCGTGGAGAAGTAAAGGTCTTCATGTACACCCATTTCAATTGGCACCCATTTGACCGCATAGATGACTCGGATCCAAGCAAGACATACGACGCGTTTGTATCGTTCAGCGGTAACGATTACCAATGGGTTGTGAACATGTTGCAAGAGCGACTCGAAAATCACGACCTTCCTTACAAACTATGCATTCATCAACGTGACTTTCTAGTGGGCGCACCAATCCAGGAAAACATTCTGAACAGCGTCGACCAAAGTAAACGCATGCTCATGGTGCTATCTCGGGACTTTTTAAGGAGCGAGTGGTGCCTGCTGGAGTTTCGCGCCGCGCATCGTAAGGTGTTAGAGGAACGCATGAATTATCTGATAATTATTCTGTTTGATGACGTCAACATGGATGAGCTTGATGACGAAATGAAGCTGTACATGCGTACTAACACTTATCCCAGTGTCAGTAACAAGTGGTTTGGGGAGAAGTTGTATTACGCGATGCCGCAAAGTACTGTGGCAGAGTTTAGAGCGAGACATCTCTCAAGCACTTCCTCGAATGCTGGTTTAGAATATTCAACCGAGACAGTGCACAAGAATGGCGCATACCTAAAAGAAACTGTTATTTTAGAGTGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P08953	Protein toll OS=Drosophila melanogaster OX=7227 GN=Tl PE=1 SV=1
Q9V477	Toll-like receptor Tollo OS=Drosophila melanogaster OX=7227 GN=Tollo PE=1 SV=1
Q689D1	Toll-like receptor 2 OS=Canis lupus familiaris OX=9615 GN=TLR2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003005 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13855 all species →	LRR_8	Leucine rich repeat	Repeat	Interproscan
PF13306 all species →	LRR_5	BspA type Leucine rich repeat region (6 copies)	Repeat	Interproscan
PF01582 all species →	TIR	TIR domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR032675 all species →	Homologous_superfamily	Leucine-rich repeat domain superfamily	Interproscan
IPR035897 all species →	Homologous_superfamily	Toll/interleukin-1 receptor homology (TIR) domain superfamily	Interproscan
IPR001611 all species →	Repeat	Leucine-rich repeat	Interproscan
IPR000157 all species →	Domain	Toll/interleukin-1 receptor homology (TIR) domain	Interproscan
IPR026906 all species →	Repeat	BspA-type LRR region	Interproscan
IPR003591 all species →	Repeat	Leucine-rich repeat, typical subtype	Interproscan
IPR017241 all species →	Family	Toll-like receptor	Interproscan
IPR000483 all species →	Domain	Cysteine-rich flanking region, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24365 all species →	TOLL-LIKE RECEPTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0002224 all species →	Biological Process	toll-like receptor signaling pathway	Interproscan
GO:0004888 all species →	Molecular Function	transmembrane signaling receptor activity	Interproscan
GO:0005887 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006954 all species →	Biological Process	inflammatory response	Interproscan
GO:0006955 all species →	Biological Process	immune response	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0038023 all species →	Molecular Function	signaling receptor activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K18809	TL; protein toll	-	Toll and Imd signaling pathway	ko04624	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of evm.model.Ap11.926 across 49 RNA-seq samples of Astrangia poculata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

49Samples

3TPM > 0

4Conditions

157.0Max TPM

8.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organism · cold control	14	1	11.06	154.79
whole organism · heat control	12	1	8.47	101.67
whole organism · cold challenge	12	0	0.00	0.00
whole organism · heat challenge	11	1	14.27	156.99

Per sample · hover a bar for the full sample record

Show the sample table (49 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR10674748	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	154.79
SRR10674714	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674715	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674724	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674733	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674734	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674735	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674736	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674737	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674739	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674743	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674746	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674747	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674750	whole organism · cold control	whole organism	not recorded	cold control	SRP237293	0.00
SRR10674717	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	101.67
SRR10674706	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674707	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674708	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674718	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674720	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674721	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674725	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674731	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674741	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674752	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674753	whole organism · heat control	whole organism	not recorded	heat control	SRP237293	0.00
SRR10674711	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674712	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674713	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674722	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674723	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674730	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674732	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674738	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674740	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674744	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674745	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674749	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293	0.00
SRR10674726	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	156.99
SRR10674709	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674710	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674716	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674719	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674727	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674728	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674729	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674742	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674751	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00
SRR10674754	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293	0.00

Source: CnidoSite RNA-seq expression matrices (APOCU_TPM, StringTie quantification over 49 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.