Gene detail

Detailed information of evm.model.Ap12.1722 in Astrangia poculata

Genomic Location: Ap12:18055416...18063181
NR annotation: XP_020600841.1, eukaryotic elongation factor 2 kinase-like [Orbicella faveolata]
Species Astrangia poculata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap12.1722

atgagtaacagcgaaagtgaaagctgtaatggccaagaaaggaaatcagattgtgacagctgcagtcatttggaaaaagaaatactggatgattggagtgatgaaataggatcattaactgatgatgacactacaaatacaaatgtagcagctgaaaatcaggataatgaaattaatactgatgggcttttaaaacaaactaatttagtaaatcatgagacagctaaggaaggtaaaaaacctcatcgtccaaaactgcagcaccatttgagttggcagagtgctctcaaaaaagccaagaatttgccagatccttgggaagagtttcacatagatgactcatatcctacagaaattgccataagacatcggtataatgctctgaagaaaaattgggtacaagatgaagtcagagtcaaaatggagtcattgccatttgatcaaggagccatgagagagtgtttcagattgaaaaagttgtcaaatttctcaaaacacatgaactggaagcatgcagcaaattatgtgagcaaacgttacattgatgaggttagcagagatgtatattttgatgatgtgagactacagatggatgccaagctctggggtgaagagtataatagatacaacccaccaaaaaaggtggatatcttccaagtctgtgttattgaaatgaaggacagggaagggtcaccactgtatcacttggagcattttattgaaggaacatatatcaagtacaactcaaattctggctatgtactgcaggatgaaactcttcgctgttctcctcaggcttttagccattttacatttgagagatctggtcatcagttgattgtggttgatattcaaggtgttggtgacctgtacactgacccacagattcacacagcagatggaaagggttatggtgaagccaacttgggtccaagaggaatgggattgtttttcagttctcacaaatgcaacaaaatctgtgaaagccttggactatcaccatttgacctcagtgaaaaagaaatggatcggattgatgcagttctgaaaaacatccaagactccagcacaatcctcagaagtagtgaagactgtatttcccctgggtaccgcaaaatctctgccatatttgatatgactgaatacctggcccagtctcctcctccttctccttctaactctgagccagactcccctcgttcatcagtttcatcatataatgaagtgtcaagcttttcacgacagatctctgacccagaatcatcggaaactgaaagtgatcaaagtgatgttttcactgaaaatgaggatgaagatacccaaaaattatttgctaaaaacctggtacataaagcatctagtgtgtttgctgaggttgaactgcttgaaaaagtccgcatagaggttcagagaaggcaaaagagtgtttctgttcttggacaggttcatctcgagctagctaaatacaatgagatgggtcgtttcactgagcatgagccacagatggactgtgccatgtttcatttagaacaagctgcagcttgttctgttttaccagctttagttacaatggctgagatttatttacagctgcctcacgagatactagcctcagcaactgttcaggagtctgatgaggcaacaaaccggggggtggagtacatgttacaggcggctgtcttgggagacagacaagccatggtgtacatggcaaaggcatatgaaactgggacaggattgggcactcaaagggaacgctcctgggaagaggcagtcaagtggtatcagaatgccattgatgttgtgtatgaagacgatgatccacagaacacactcttcacagatcctaactacgtgctatgcgccaaacaagctaacttgtaccaacaaggaggttatgggcttgacaaacagcctcaagaagcgggcgatttgtactcttcagccggagatttcgcgcttgctgctatgaagggaaaactggctaacaagtactatgcactggctgaagaggcctgggctgaggtcgaggaataa

Transcript

evm.model.Ap12.1722

ATGAGTAACAGCGAAAGTGAAAGCTGTAATGGCCAAGAAAGGAAATCAGATTGTGACAGCTGCAGTCATTTGGAAAAAGAAATACTGGATGATTGGAGTGATGAAATAGGATCATTAACTGATGATGACACTACAAATACAAATGTAGCAGCTGAAAATCAGGATAATGAAATTAATACTGATGGGCTTTTAAAACAAACTAATTTAGTAAATCATGAGACAGCTAAGGAAGGTAAAAAACCTCATCGTCCAAAACTGCAGCACCATTTGAGTTGGCAGAGTGCTCTCAAAAAAGCCAAGAATTTGCCAGATCCTTGGGAAGAGTTTCACATAGATGACTCATATCCTACAGAAATTGCCATAAGACATCGGTATAATGCTCTGAAGAAAAATTGGGTACAAGATGAAGTCAGAGTCAAAATGGAGTCATTGCCATTTGATCAAGGAGCCATGAGAGAGTGTTTCAGATTGAAAAAGTTGTCAAATTTCTCAAAACACATGAACTGGAAGCATGCAGCAAATTATGTGAGCAAACGTTACATTGATGAGGTTAGCAGAGATGTATATTTTGATGATGTGAGACTACAGATGGATGCCAAGCTCTGGGGTGAAGAGTATAATAGATACAACCCACCAAAAAAGGTGGATATCTTCCAAGTCTGTGTTATTGAAATGAAGGACAGGGAAGGGTCACCACTGTATCACTTGGAGCATTTTATTGAAGGAACATATATCAAGTACAACTCAAATTCTGGCTATGTACTGCAGGATGAAACTCTTCGCTGTTCTCCTCAGGCTTTTAGCCATTTTACATTTGAGAGATCTGGTCATCAGTTGATTGTGGTTGATATTCAAGGTGTTGGTGACCTGTACACTGACCCACAGATTCACACAGCAGATGGAAAGGGTTATGGTGAAGCCAACTTGGGTCCAAGAGGAATGGGATTGTTTTTCAGTTCTCACAAATGCAACAAAATCTGTGAAAGCCTTGGACTATCACCATTTGACCTCAGTGAAAAAGAAATGGATCGGATTGATGCAGTTCTGAAAAACATCCAAGACTCCAGCACAATCCTCAGAAGTAGTGAAGACTGTATTTCCCCTGGGTACCGCAAAATCTCTGCCATATTTGATATGACTGAATACCTGGCCCAGTCTCCTCCTCCTTCTCCTTCTAACTCTGAGCCAGACTCCCCTCGTTCATCAGTTTCATCATATAATGAAGTGTCAAGCTTTTCACGACAGATCTCTGACCCAGAATCATCGGAAACTGAAAGTGATCAAAGTGATGTTTTCACTGAAAATGAGGATGAAGATACCCAAAAATTATTTGCTAAAAACCTGGTACATAAAGCATCTAGTGTGTTTGCTGAGGTTGAACTGCTTGAAAAAGTCCGCATAGAGGTTCAGAGAAGGCAAAAGAGTGTTTCTGTTCTTGGACAGGTTCATCTCGAGCTAGCTAAATACAATGAGATGGGTCGTTTCACTGAGCATGAGCCACAGATGGACTGTGCCATGTTTCATTTAGAACAAGCTGCAGCTTGTTCTGTTTTACCAGCTTTAGTTACAATGGCTGAGATTTATTTACAGCTGCCTCACGAGATACTAGCCTCAGCAACTGTTCAGGAGTCTGATGAGGCAACAAACCGGGGGGTGGAGTACATGTTACAGGCGGCTGTCTTGGGAGACAGACAAGCCATGGTGTACATGGCAAAGGCATATGAAACTGGGACAGGATTGGGCACTCAAAGGGAACGCTCCTGGGAAGAGGCAGTCAAGTGGTATCAGAATGCCATTGATGTTGTGTATGAAGACGATGATCCACAGAACACACTCTTCACAGATCCTAACTACGTGCTATGCGCCAAACAAGCTAACTTGTACCAACAAGGAGGTTATGGGCTTGACAAACAGCCTCAAGAAGCGGGCGATTTGTACTCTTCAGCCGGAGATTTCGCGCTTGCTGCTATGAAGGGAAAACTGGCTAACAAGTACTATGCACTGGCTGAAGAGGCCTGGGCTGAGGTCGAGGAATAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O00418	Eukaryotic elongation factor 2 kinase OS=Homo sapiens OX=9606 GN=EEF2K PE=1 SV=2
P70531	Eukaryotic elongation factor 2 kinase OS=Rattus norvegicus OX=10116 GN=Eef2k PE=1 SV=1
O08796	Eukaryotic elongation factor 2 kinase OS=Mus musculus OX=10090 GN=Eef2k PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004698 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02816 all species →	Alpha_kinase	Alpha-kinase family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR004166 all species →	Domain	Alpha-type protein kinase, alpha-kinase domain	Interproscan
IPR047588 all species →	Domain	Eukaryotic elongation factor 2 kinase, alpha-kinase domain	Interproscan
IPR017400 all species →	Family	Eukaryotic elongation factor 2 kinase	Interproscan
IPR051852 all species →	Family	Alpha-type Protein Kinase	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR011990 all species →	Homologous_superfamily	Tetratricopeptide-like helical domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45992 all species →	EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004686 all species →	Molecular Function	elongation factor-2 kinase activity	Interproscan
GO:0005509 all species →	Molecular Function	calcium ion binding	Interproscan
GO:0005516 all species →	Molecular Function	calmodulin binding	Interproscan
GO:0031037 all species →	Biological Process	myosin II filament disassembly	Interproscan
GO:1903013 all species →	Biological Process	response to differentiation-inducing factor 1	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08292	EEF2K; elongation factor 2 kinase	EC:2.7.11.20	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of evm.model.Ap12.1722 across 49 RNA-seq samples of Astrangia poculata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

49Samples

0TPM > 0

4Conditions

0.0Max TPM

0.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
whole organism · cold control	14	0	0.00	0.00
whole organism · heat control	12	0	0.00	0.00
whole organism · cold challenge	12	0	0.00	0.00
whole organism · heat challenge	11	0	0.00	0.00

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study
SRR10674714	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674715	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674724	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674733	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674734	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674735	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674736	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674737	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674739	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674743	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674746	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674747	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674748	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674750	whole organism · cold control	whole organism	not recorded	cold control	SRP237293
SRR10674706	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674707	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674708	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674717	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674718	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674720	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674721	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674725	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674731	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674741	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674752	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674753	whole organism · heat control	whole organism	not recorded	heat control	SRP237293
SRR10674711	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674712	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674713	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674722	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674723	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674730	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674732	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674738	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674740	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674744	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674745	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674749	whole organism · cold challenge	whole organism	not recorded	cold challenge	SRP237293
SRR10674709	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674710	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674716	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674719	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674726	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674727	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674728	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674729	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674742	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674751	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293
SRR10674754	whole organism · heat challenge	whole organism	not recorded	heat challenge	SRP237293

Source: CnidoSite RNA-seq expression matrices (APOCU_TPM, StringTie quantification over 49 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.