Genomic Location: Ap12:26759055...26776646
NR annotation: XP_020620792.1, apoptotic protease-activating factor 1-like [Orbicella faveolata]
Species abbreviation APOCU · all data for this species · gene families
| CDS |
| evm.model.Ap12.2529 |
| Transcript |
| evm.model.Ap12.2529 |
| Protein |
| evm.model.Ap12.2529 |
| UniProt accession | Description |
|---|---|
| O14727 | Apoptotic protease-activating factor 1 OS=Homo sapiens OX=9606 GN=APAF1 PE=1 SV=2 |
| O88879 | Apoptotic protease-activating factor 1 OS=Mus musculus OX=10090 GN=Apaf1 PE=1 SV=3 |
| Q9I9H8 | Apoptotic protease-activating factor 1 OS=Danio rerio OX=7955 GN=apaf1 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004274 (this species only) |
| Ubiquitin family | UBD|Other|Beta-prp · all ubiquitin genes in this species |
| Ubiquitin family | E3|E3 adaptor Cullin RING|CDC20 · all ubiquitin genes in this species |
| Ubiquitin family | E3|E3 adaptor Cullin RING|DWD · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF17908 all species → | APAF1_C | APAF-1 helical domain | Domain | Interproscan |
| PF00619 all species → | CARD | Caspase recruitment domain | Domain | Interproscan |
| PF00931 all species → | NB-ARC | NB-ARC domain | Domain | Interproscan |
| PF21296 all species → | APAF-1-like_WHD | Apoptotic protease-activating factor 1-like, winged-helix domain | Domain | Interproscan |
| PF12894 all species → | ANAPC4_WD40 | Anaphase-promoting complex subunit 4 WD40 domain | Repeat | Interproscan |
| PF00400 all species → | WD40 | WD domain, G-beta repeat | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR015943 all species → | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR001680 all species → | Repeat | WD40 repeat | Interproscan |
| IPR041452 all species → | Domain | APAF-1 helical domain | Interproscan |
| IPR001315 all species → | Domain | CARD domain | Interproscan |
| IPR036322 all species → | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR002182 all species → | Domain | NB-ARC | Interproscan |
| IPR036388 all species → | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| IPR019775 all species → | Conserved_site | WD40 repeat, conserved site | Interproscan |
| IPR011029 all species → | Homologous_superfamily | Death-like domain superfamily | Interproscan |
| IPR042197 all species → | Homologous_superfamily | Apoptotic protease-activating factors, helical domain | Interproscan |
| IPR048975 all species → | Domain | Apoptotic protease-activating factor 1, winged-helix domain | Interproscan |
| IPR020472 all species → | Repeat | G-protein beta WD-40 repeat | Interproscan |
| IPR024977 all species → | Domain | Anaphase-promoting complex subunit 4-like, WD40 domain | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22845 all species → | APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0042981 all species → | Biological Process | regulation of apoptotic process | Interproscan |
| GO:0043531 all species → | Molecular Function | ADP binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K02084 | APAF1; apoptotic protease-activating factor | - | Platinum drug resistance | ko01524 | deepkoala |
