Gene detail

Detailed information of evm.model.Ap12.520 in Astrangia poculata

Genomic Location: Ap12:5592615...5626216
NR annotation: XP_022780261.1, growth factor receptor-bound protein 2-like [Stylophora pistillata]
Species Astrangia poculata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P62993	Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1
Q60631	Growth factor receptor-bound protein 2 OS=Mus musculus OX=10090 GN=Grb2 PE=1 SV=1
Q5R4J7	Growth factor receptor-bound protein 2 OS=Pongo abelii OX=9601 GN=GRB2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001820 (this species only)
Ubiquitin family	UBD\|Other\|SH3 · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00018 all species →	SH3_1	SH3 domain	Domain	Interproscan
PF14604 all species →	SH3_9	Variant SH3 domain	Domain	Interproscan
PF00017 all species →	SH2	SH2 domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000980 all species →	Domain	SH2 domain	Interproscan
IPR001452 all species →	Domain	SH3 domain	Interproscan
IPR043539 all species →	Family	Grb2-like	Interproscan
IPR036028 all species →	Homologous_superfamily	SH3-like domain superfamily	Interproscan
IPR036860 all species →	Homologous_superfamily	SH2 domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR46037 all species →	PROTEIN ENHANCER OF SEVENLESS 2B	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0001784 all species →	Molecular Function	phosphotyrosine residue binding	Interproscan
GO:0005154 all species →	Molecular Function	epidermal growth factor receptor binding	Interproscan
GO:0005654 all species →	Cellular Component	nucleoplasm	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0008180 all species →	Cellular Component	COP9 signalosome	Interproscan
GO:0043408 all species →	Biological Process	regulation of MAPK cascade	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04364	GRB2; growth factor receptor-bound protein 2	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.