Gene detail

Detailed information of evm.model.Ap12.953 in Astrangia poculata

Genomic Location: Ap12:10198653...10229867
NR annotation: XP_020601823.1, tuberin-like [Orbicella faveolata]
Species abbreviation APOCU · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap12.953

atgtatagtgaccatggctctgatgtaatgttattgcgaggttcagtgtttttcattggaatgtgtctgtggggctcgcagaaggtaccaaacctcaagtactccaattcaactgtcttgccttctatgttacaggccctgtcatgccatcacagcttggtggccctggaagtgaccttgtcattacaaagactggtgaagaagtatggtcatgagcttcatgtagtggcctgggatgcagtgttagacatcacagaagctttacaacagcagattgaggtgtatagccaaggagataatgccctgatagaaaattttcacatcctgttgaccagtatagaagacctttacgaggctggaaagttcaatggaccagaggaaaggttctttggtttagtagagaagagtgctagtatgcgccctgaaaagtctcttcatatcttggtttcgttcaaggctcagacagttcatccagcacaagtcggttggctcactaaccttcacaatcttatggaaaaatacttcagatatgaaatccgcactagcgttagagtgaaagtcctcactgttctatcatctgtacttacgtcatatggtcactggtacgaggaagagcttttagagtgtgcagtgttaccgtatctaaaccacattgctgaagaccaagatgtaacagttcggaatgttgcagtgcagatccttttggacttgtgccagatgtgtgactctcagaagtgtcaagacttcctggacattattgaaaaggttctcagtagacacgtggaactacaaggaaaacaccttccactagagcagcagcaacagttgttgcaagaggaaaaagaattaaaagatgttaaaacagcggtcaatggactggtggaggtctttaagctcaagttgtttcgtttgcctcatggtcatgctgtacgaacgtttgaactgttggtctcgcacatgaaggcacactatttccatggttacagtacatacattgctagtgtcatcagaaacttggcgtttgagtgcttcctgagtttgcggtgtgactccagtttacggcttggtttatacaacgccagtggagaggaagacacctcaaagtttagtccttactttacttgtttgcagagcgattccgacacgaagacctcagcatcttcgcatcttggtgtgataccctactcggatgtgtttcaagttattttgaactgtttgcagtatgagtgggactggacagtactggagcatgttttgactgcactaccaaaggtcctacaaaataagagccttattctgtcagccaatcctgccttgaacaccatgacagcagtactctgccacatggtttcagacccttcgtgtatcattgacctccgtcgtgttcctcatggtgttggcagagcgggattacaagctttgatatttccagttttaacagttcttgctacatatcactcgagcttggacagagggcggcagtttgagttagtgaagacgttagagctgggtttggtgaccaagtgtgctgtcctgtgtgtttcgtcattgacgctgtgtaccatggaaatgcaggcagtgatgaaaagtcttcttccagcccttttggtccggttgactcagatttctgctacggtttcaatggcagcacctatgctagagtttctctcaggcttggttcacttgcctcatttgtatgctagtttccaggacagtcagtacaaaagcgtgttcgccatttgtctgccttacactgatcctttcaagtattctcagtacaccgtgacacttgcctatcacgtgatcgccgcgtggttcgtacgatcacgtgtagcttaccgcaaagcatttgttggatttgtgagcaagggtctaaaatcaagtgccataatcccggagcgttatgactctagaccagacagccccgctttaacagtatccagatcacgcagtggaagctccaccaatcagccctcaccccaggtccttcatcggtctaattcgcccgttattcacaaggagactgacgctgcgtgtgaactgcattccgagatgagtgaagtgtgtatggacatgatggccagatacacgtttgctccttgtatgtcacagccgaacaggactaaagctgtggagttcatgctggccaacggtcactcacgcacctggatgatcgctaacactattgtgacgataacaacttctggtacgtacattgggctggatggtgtgtgcgacaactgtctgacactgagacaaaggactacgaatgttacacacaaagaaaagtcaaaggctgatacaaatgtcaaacagaggaacattgcatcagatggttcgacagaggattctgcttcccagacttccagtgaccaaacacatggcgcagcagagcagagcagcatcgaaggatccgtgaagcctgatactccaaagacagaagagattcgtagcagcatcctttctgaccggcgacacagcgagccgtttgttcctattgatccacagaactgtcagtgtgtttgccaaggttgggccgaaatctttatccgtcgacccagcggaaatatctcttgggtcatgcgcattcagaatagggctacgtcaccatgtttggatggtgacgtcagtactgctattgtggacgaccctcaagttggtgactttttatctccacacagtgaaaagcacggagaggtcttaagcaccagcacggagagcggctcggttatcgttgacatggtgcaacgaatcaaaaccccagaggggatgggtggcgtcacatcccatgacacagtaaatgagaaatccctccctactcttgactggcagcttgacagtactgatggagacaaaacccttggacctcctcagctagacccagtcctattctactcgccagccggaagcacgggtactccaccaagcacacctgtggggtctgtggattctgagttctttgaaggaagggacaggctcctcagcaggagtcctaggaagggacctaatgtttttaggatgagagagtcagaatgctctgacgtagctggaagtttggacaccactccaactgaggatgtccctcccagtaagaccagaaaacagatgcactttgaaaagcctgagctgggtgtctcccccgctgaccatttcacggtctcctctctaccaggactgagtcacctggagcaaaggagaagagacgaaaccagatatctctcgtcatccgagatgtaccggcttgcaagtgacgaggagagtgtacagtcactcaatgttgaagacagtgcggaccacacaggagaccaacaaaagatggagactccagaaacagaagcgcctcaacatcgtacagtcagcccggctaagaaagcagagaggccaaaatccctcaacgtagagcctccagtgataagggaaagccccgagtttgctttagacagagtattcactgaacacgaaaaattacaatttactacgagtctcgattccggcgcaaacagaagtcaccacattccctcgcggtcaccacgttccccacggggacatgcgcaagacccgggccctagttcccaggctcttaagaaagtcaagttgaaaaagtcttctagtatcagttcaccaattagaagtaggagagatttggatcattcggagcattctccattcacgtcgcctcgccagggaagaagtgtgaaaagcaaggaagctgaggataggcatggttatacgaacagcgtcggcgatccgaagaaaagtacgtcatcaccggagttgtcctcgccacccgcattccctaaagtgccaacactcggtaaaagcgagtctgccaagcggctggcatctcgatccagattgatgcccattggaggggcccctcagtccacaagcaagtcatctagaccagcaccattggtcggagacctctcagatacgggacctaaagagcctcctatattggtgaccccgtcagagtccttcaggtatcccctggacccttgttttgtctttctgcagttgtaccatgcgtccttcttgggtccagttcacgagaagcctcagcctcttcctgatggcgaggttattgaacgagccatcaaatgcctggaccgcattcctccgtatgatacacacaagatcggcgtcatctatgtggggcctgggcagcacgataacgaggctgcgatcttacgcaatgtttacggatcgtcccgttacatgaagttcctagcgggtctcgggacgcttgttcgtctgagggattgtccgcccgccgagatctacactgggggactggacaggaatggagcggacggtgaatttgcttacagttggcaggatgatatttgtcaagttattttccatgtggcgacgttgatgccgaccagagactcggacccaggctgcaactccaaaaagatgcacattggtaacgactttgtaaccatcgtgtataacgactcacaacaggcggtcaagtttggcagaattaagggtcagttcaattttgctgaagtgttgattaaaccgctcgataacgcgtccaacatggtgaccgtgagattcaaagatgagctgaaggatctactcactgacacagggactagagtcatctcggataacaaccttcctcgcttggtcaggcagcttgtcgtacatatcaatatggcttctgttattcatcaaagtcagaagcggccaacagacgcgtatggctgtaactggcttgagcgattacgtcagattaagcgcgtgcgcaccaaggcagcggcggagaacttctcagttcccagcagtcctatcggcaagatatctcctttatcacttgggatgcgcctgtcgtctctaccggtcaccggtcttacagacttcacagagtacatgaaatag

Transcript

evm.model.Ap12.953

ATGTATAGTGACCATGGCTCTGATGTAATGTTATTGCGAGGTTCAGTGTTTTTCATTGGAATGTGTCTGTGGGGCTCGCAGAAGGTACCAAACCTCAAGTACTCCAATTCAACTGTCTTGCCTTCTATGTTACAGGCCCTGTCATGCCATCACAGCTTGGTGGCCCTGGAAGTGACCTTGTCATTACAAAGACTGGTGAAGAAGTATGGTCATGAGCTTCATGTAGTGGCCTGGGATGCAGTGTTAGACATCACAGAAGCTTTACAACAGCAGATTGAGGTGTATAGCCAAGGAGATAATGCCCTGATAGAAAATTTTCACATCCTGTTGACCAGTATAGAAGACCTTTACGAGGCTGGAAAGTTCAATGGACCAGAGGAAAGGTTCTTTGGTTTAGTAGAGAAGAGTGCTAGTATGCGCCCTGAAAAGTCTCTTCATATCTTGGTTTCGTTCAAGGCTCAGACAGTTCATCCAGCACAAGTCGGTTGGCTCACTAACCTTCACAATCTTATGGAAAAATACTTCAGATATGAAATCCGCACTAGCGTTAGAGTGAAAGTCCTCACTGTTCTATCATCTGTACTTACGTCATATGGTCACTGGTACGAGGAAGAGCTTTTAGAGTGTGCAGTGTTACCGTATCTAAACCACATTGCTGAAGACCAAGATGTAACAGTTCGGAATGTTGCAGTGCAGATCCTTTTGGACTTGTGCCAGATGTGTGACTCTCAGAAGTGTCAAGACTTCCTGGACATTATTGAAAAGGTTCTCAGTAGACACGTGGAACTACAAGGAAAACACCTTCCACTAGAGCAGCAGCAACAGTTGTTGCAAGAGGAAAAAGAATTAAAAGATGTTAAAACAGCGGTCAATGGACTGGTGGAGGTCTTTAAGCTCAAGTTGTTTCGTTTGCCTCATGGTCATGCTGTACGAACGTTTGAACTGTTGGTCTCGCACATGAAGGCACACTATTTCCATGGTTACAGTACATACATTGCTAGTGTCATCAGAAACTTGGCGTTTGAGTGCTTCCTGAGTTTGCGGTGTGACTCCAGTTTACGGCTTGGTTTATACAACGCCAGTGGAGAGGAAGACACCTCAAAGTTTAGTCCTTACTTTACTTGTTTGCAGAGCGATTCCGACACGAAGACCTCAGCATCTTCGCATCTTGGTGTGATACCCTACTCGGATGTGTTTCAAGTTATTTTGAACTGTTTGCAGTATGAGTGGGACTGGACAGTACTGGAGCATGTTTTGACTGCACTACCAAAGGTCCTACAAAATAAGAGCCTTATTCTGTCAGCCAATCCTGCCTTGAACACCATGACAGCAGTACTCTGCCACATGGTTTCAGACCCTTCGTGTATCATTGACCTCCGTCGTGTTCCTCATGGTGTTGGCAGAGCGGGATTACAAGCTTTGATATTTCCAGTTTTAACAGTTCTTGCTACATATCACTCGAGCTTGGACAGAGGGCGGCAGTTTGAGTTAGTGAAGACGTTAGAGCTGGGTTTGGTGACCAAGTGTGCTGTCCTGTGTGTTTCGTCATTGACGCTGTGTACCATGGAAATGCAGGCAGTGATGAAAAGTCTTCTTCCAGCCCTTTTGGTCCGGTTGACTCAGATTTCTGCTACGGTTTCAATGGCAGCACCTATGCTAGAGTTTCTCTCAGGCTTGGTTCACTTGCCTCATTTGTATGCTAGTTTCCAGGACAGTCAGTACAAAAGCGTGTTCGCCATTTGTCTGCCTTACACTGATCCTTTCAAGTATTCTCAGTACACCGTGACACTTGCCTATCACGTGATCGCCGCGTGGTTCGTACGATCACGTGTAGCTTACCGCAAAGCATTTGTTGGATTTGTGAGCAAGGGTCTAAAATCAAGTGCCATAATCCCGGAGCGTTATGACTCTAGACCAGACAGCCCCGCTTTAACAGTATCCAGATCACGCAGTGGAAGCTCCACCAATCAGCCCTCACCCCAGGTCCTTCATCGGTCTAATTCGCCCGTTATTCACAAGGAGACTGACGCTGCGTGTGAACTGCATTCCGAGATGAGTGAAGTGTGTATGGACATGATGGCCAGATACACGTTTGCTCCTTGTATGTCACAGCCGAACAGGACTAAAGCTGTGGAGTTCATGCTGGCCAACGGTCACTCACGCACCTGGATGATCGCTAACACTATTGTGACGATAACAACTTCTGGTACGTACATTGGGCTGGATGGTGTGTGCGACAACTGTCTGACACTGAGACAAAGGACTACGAATGTTACACACAAAGAAAAGTCAAAGGCTGATACAAATGTCAAACAGAGGAACATTGCATCAGATGGTTCGACAGAGGATTCTGCTTCCCAGACTTCCAGTGACCAAACACATGGCGCAGCAGAGCAGAGCAGCATCGAAGGATCCGTGAAGCCTGATACTCCAAAGACAGAAGAGATTCGTAGCAGCATCCTTTCTGACCGGCGACACAGCGAGCCGTTTGTTCCTATTGATCCACAGAACTGTCAGTGTGTTTGCCAAGGTTGGGCCGAAATCTTTATCCGTCGACCCAGCGGAAATATCTCTTGGGTCATGCGCATTCAGAATAGGGCTACGTCACCATGTTTGGATGGTGACGTCAGTACTGCTATTGTGGACGACCCTCAAGTTGGTGACTTTTTATCTCCACACAGTGAAAAGCACGGAGAGGTCTTAAGCACCAGCACGGAGAGCGGCTCGGTTATCGTTGACATGGTGCAACGAATCAAAACCCCAGAGGGGATGGGTGGCGTCACATCCCATGACACAGTAAATGAGAAATCCCTCCCTACTCTTGACTGGCAGCTTGACAGTACTGATGGAGACAAAACCCTTGGACCTCCTCAGCTAGACCCAGTCCTATTCTACTCGCCAGCCGGAAGCACGGGTACTCCACCAAGCACACCTGTGGGGTCTGTGGATTCTGAGTTCTTTGAAGGAAGGGACAGGCTCCTCAGCAGGAGTCCTAGGAAGGGACCTAATGTTTTTAGGATGAGAGAGTCAGAATGCTCTGACGTAGCTGGAAGTTTGGACACCACTCCAACTGAGGATGTCCCTCCCAGTAAGACCAGAAAACAGATGCACTTTGAAAAGCCTGAGCTGGGTGTCTCCCCCGCTGACCATTTCACGGTCTCCTCTCTACCAGGACTGAGTCACCTGGAGCAAAGGAGAAGAGACGAAACCAGATATCTCTCGTCATCCGAGATGTACCGGCTTGCAAGTGACGAGGAGAGTGTACAGTCACTCAATGTTGAAGACAGTGCGGACCACACAGGAGACCAACAAAAGATGGAGACTCCAGAAACAGAAGCGCCTCAACATCGTACAGTCAGCCCGGCTAAGAAAGCAGAGAGGCCAAAATCCCTCAACGTAGAGCCTCCAGTGATAAGGGAAAGCCCCGAGTTTGCTTTAGACAGAGTATTCACTGAACACGAAAAATTACAATTTACTACGAGTCTCGATTCCGGCGCAAACAGAAGTCACCACATTCCCTCGCGGTCACCACGTTCCCCACGGGGACATGCGCAAGACCCGGGCCCTAGTTCCCAGGCTCTTAAGAAAGTCAAGTTGAAAAAGTCTTCTAGTATCAGTTCACCAATTAGAAGTAGGAGAGATTTGGATCATTCGGAGCATTCTCCATTCACGTCGCCTCGCCAGGGAAGAAGTGTGAAAAGCAAGGAAGCTGAGGATAGGCATGGTTATACGAACAGCGTCGGCGATCCGAAGAAAAGTACGTCATCACCGGAGTTGTCCTCGCCACCCGCATTCCCTAAAGTGCCAACACTCGGTAAAAGCGAGTCTGCCAAGCGGCTGGCATCTCGATCCAGATTGATGCCCATTGGAGGGGCCCCTCAGTCCACAAGCAAGTCATCTAGACCAGCACCATTGGTCGGAGACCTCTCAGATACGGGACCTAAAGAGCCTCCTATATTGGTGACCCCGTCAGAGTCCTTCAGGTATCCCCTGGACCCTTGTTTTGTCTTTCTGCAGTTGTACCATGCGTCCTTCTTGGGTCCAGTTCACGAGAAGCCTCAGCCTCTTCCTGATGGCGAGGTTATTGAACGAGCCATCAAATGCCTGGACCGCATTCCTCCGTATGATACACACAAGATCGGCGTCATCTATGTGGGGCCTGGGCAGCACGATAACGAGGCTGCGATCTTACGCAATGTTTACGGATCGTCCCGTTACATGAAGTTCCTAGCGGGTCTCGGGACGCTTGTTCGTCTGAGGGATTGTCCGCCCGCCGAGATCTACACTGGGGGACTGGACAGGAATGGAGCGGACGGTGAATTTGCTTACAGTTGGCAGGATGATATTTGTCAAGTTATTTTCCATGTGGCGACGTTGATGCCGACCAGAGACTCGGACCCAGGCTGCAACTCCAAAAAGATGCACATTGGTAACGACTTTGTAACCATCGTGTATAACGACTCACAACAGGCGGTCAAGTTTGGCAGAATTAAGGGTCAGTTCAATTTTGCTGAAGTGTTGATTAAACCGCTCGATAACGCGTCCAACATGGTGACCGTGAGATTCAAAGATGAGCTGAAGGATCTACTCACTGACACAGGGACTAGAGTCATCTCGGATAACAACCTTCCTCGCTTGGTCAGGCAGCTTGTCGTACATATCAATATGGCTTCTGTTATTCATCAAAGTCAGAAGCGGCCAACAGACGCGTATGGCTGTAACTGGCTTGAGCGATTACGTCAGATTAAGCGCGTGCGCACCAAGGCAGCGGCGGAGAACTTCTCAGTTCCCAGCAGTCCTATCGGCAAGATATCTCCTTTATCACTTGGGATGCGCCTGTCGTCTCTACCGGTCACCGGTCTTACAGACTTCACAGAGTACATGAAATAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P49815	Tuberin OS=Homo sapiens OX=9606 GN=TSC2 PE=1 SV=2
P49816	Tuberin OS=Rattus norvegicus OX=10116 GN=Tsc2 PE=1 SV=1
Q61037	Tuberin OS=Mus musculus OX=10090 GN=Tsc2 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002253 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF11864 all species →	DUF3384	Domain of unknown function (DUF3384)	Family	Interproscan
PF03542 all species →	Tuberin	Tuberin	Family	Interproscan
PF02145 all species →	Rap_GAP	Rap/ran-GAP	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR035974 all species →	Homologous_superfamily	Rap/Ran-GAP superfamily	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR024584 all species →	Domain	Tuberin, N-terminal	Interproscan
IPR018515 all species →	Domain	Tuberin-type domain	Interproscan
IPR000331 all species →	Domain	Rap/Ran-GAP domain	Interproscan
IPR003913 all species →	Family	Tuberin	Interproscan
IPR021133 all species →	Repeat	HEAT, type 2	Interproscan
IPR027107 all species →	Family	Tuberin/Ral GTPase-activating protein subunit alpha	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10063 all species →	TUBERIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005096 all species →	Molecular Function	GTPase activator activity	Interproscan
GO:0051056 all species →	Biological Process	regulation of small GTPase mediated signal transduction	Interproscan
GO:0043547 all species →	Biological Process	positive regulation of GTPase activity	Interproscan
GO:0032007 all species →	Biological Process	negative regulation of TOR signaling	Interproscan
GO:0033596 all species →	Cellular Component	TSC1-TSC2 complex	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0030178 all species →	Biological Process	negative regulation of Wnt signaling pathway	Interproscan
GO:0046627 all species →	Biological Process	negative regulation of insulin receptor signaling pathway	Interproscan
GO:0051726 all species →	Biological Process	regulation of cell cycle	Interproscan
GO:0051898 all species →	Biological Process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K07207	TSC2; tuberous sclerosis 2	-	Protein phosphatases and associated proteins	ko01009	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.