Genomic Location: Ap14:19320272...19340334
NR annotation: XP_027052279.1, protein patched homolog 1-like [Pocillopora damicornis]
Species Astrangia poculata · all data for this species · gene families
| CDS |
| evm.model.Ap14.1757 |
| Transcript |
| evm.model.Ap14.1757 |
| Protein |
| evm.model.Ap14.1757 |
| UniProt accession | Description |
|---|---|
| Q98864 | Protein patched homolog 1 OS=Danio rerio OX=7955 GN=ptch1 PE=2 SV=1 |
| Q90693 | Protein patched homolog 1 OS=Gallus gallus OX=9031 GN=PTCH1 PE=1 SV=1 |
| Q13635 | Protein patched homolog 1 OS=Homo sapiens OX=9606 GN=PTCH1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002058 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02460 all species → | Patched | Patched family | Family | Interproscan |
| PF12349 all species → | Sterol-sensing | Sterol-sensing domain of SREBP cleavage-activation | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003392 all species → | Family | Protein patched/dispatched | Interproscan |
| IPR000731 all species → | Domain | Sterol-sensing domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46022 all species → | PROTEIN PATCHED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005119 all species → | Molecular Function | smoothened binding | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0008158 all species → | Molecular Function | hedgehog receptor activity | Interproscan |
| GO:0045879 all species → | Biological Process | negative regulation of smoothened signaling pathway | Interproscan |
| GO:0097108 all species → | Molecular Function | hedgehog family protein binding | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06225 | PTCH1; patched 1 | - | Basal cell carcinoma | ko05217 | deepkoala |
Transcript abundance of evm.model.Ap14.1757 across 49 RNA-seq samples of Astrangia poculata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · cold control | 14 | 0 | 0.00 | 0.00 | |
| whole organism · heat control | 12 | 0 | 0.00 | 0.00 | |
| whole organism · cold challenge | 12 | 0 | 0.00 | 0.00 | |
| whole organism · heat challenge | 11 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (APOCU_TPM,
StringTie quantification over 49 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.