Gene detail

Detailed information of evm.model.Ap2.443 in Astrangia poculata

Genomic Location: Ap2:4246522...4293056
NR annotation: XP_020615052.1, glutamate--cysteine ligase catalytic subunit-like [Orbicella faveolata]
Species Astrangia poculata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap2.443

atgtttaaagaagcattgaagaaacgagattacacagaggacgcacaaattttggtcaaggcagcttcaataataagaaaatacattttcagccacgaggcatataaatttaatggatcgttttcagaaaatagtcaagaagcgttgttaccatctaacctcaaaacctcaatattcttactttttaatggagacggtttgaaaaagcaagataagcacgagtcccaagcatgccttaccattggccagcctattgtctacaacactaagaacaaaatcaaaagaacccgatacagaaacaaggcacttttaggagcggtcacacagcttgacgagtggattgcagaagccatgtgcgagcactttgacgaagacggatttgtatcccctgcctgcctgctaaaggagaaaggacaggcatttaaagaggaaacagaaacacttgcctatttagcctccaatccgattgagtcccttgatgcagactcagtagcagtagcagtagcagtagcagtagtagtggtagtagcagtagtagtggtagtggtagtggtagtggtagtggtagtggtagtggtagtggtagtggtagtggtagtggtagtggtagtggtagtggtagtggataaaatagcattcaatatattcccatgtctccttcgacttcagttttctgaagataatttcagttcgggaaaaagaaagacgaaggttcgtggaagatcaccgcgaaattcctctcaactactcatgaagattggggataagatggttacgtacactgctttcaacgatgctattcagagcttcttaaccaatatcaagtgtgacaccgccgtaatcgtggactttgtgcggattctgaacactttacaaagcaaaatggtggaatacaagttgataaaatttgaccacgacaacgaaaaggtctacggcaatataagagccaaggaaattattgacgttttgcaagctcaggaattaaagaatcccagcaccagtatagctgattggagacctgagtattgcagttatgttgtggaaggatcacctggccagccattaggagaatgcatgagatatttcaacacggtcgaagcaaatatgagactaagacgcaagaaaattcaggaaagcctgacggagccaggagaaactgttcaaacaatcgtcgcccatcccagattaggatgtccagaatttctctatccaagttgcgagcctactccagtcggagggttatcctgttctctgttctttcctgatcagggtattttccaagctcatccacgattcagcacactgacaagaaacattcgagaaagaaggggttcaaaggttgtcatcaatattccgattttcaaagatgtgaaaacttcatcacccttcattgaaacatttcctgacgttgatgaagaaagtactagagcggcgctgccagatcatatctacatggacgccgttggttgtggaatggtaatgtgctgccttcaggcgactgtccaggcttgtaacatcagcgaagcaaggtttctgtatgatcaactgtcagcgatcagtccgatagtgatggctctgtctgcaggcactcccataattcgtggatacctggcagatacggattgccgttggagtgtgatatctgcggcaatggatgatcgaactcttgaggagagaggacttgagcctttgaaggaaaataaatttgtcattccaaaatcacgatttgactcaatcagtacatacctgtctcctgagggaaagatgtacaacgacattgaattagtctatgacaaggagatttgtcaacagctcatggatgctggtatggacgaacaactagcccgccatttcgctcacttattcatcagagatcctgtgacattgtttcgtgaacacataaatgaagacgacgagcacaactcgaatcactttgagaacatccagtccaccaactggcagaacatgcgatttaaaccgccgcctagtcctaactcttccatcggatggagagtcgagttcagacccgcagatgtgcagttaacagacttcgaaaatgccgcctacgtgacattcgctgtgcttctcacgagagtcattttgtcgatggaccttaacctacttattccgttatccaaggtggatacgaacatagacaaagcccagaagagagatgctgtccgccaggaacatttttactttaggaagacattgaagaaaagtttccttgcaaacaactgcaacgaggaccctgacgaggaatttgagctgatgacgatagacaagataatcaacggcaaggatgatgaatttccaggcctgataccgctgatcgaaagatacttggcgaccgttgatgttgacattgacacgcattgtaccatttcccaatacttgaaactgatctcgaaaagggcttctggtgaattcctgacaacagcacagtggattcgcgggttggtggaagcacatcctgactacaaaaaggactccattgttagtgaaacgatctgttatgatttgttaaatattactgatcgtgttggtcggggagaaattggagcccctggtctcttaggaaacctgacgtcgaggacaagtgacagtcttctaaagaaatgcacagaaacaaacaagaagatgaaagaaatgagaagctaa

Transcript

evm.model.Ap2.443

ATGTTTAAAGAAGCATTGAAGAAACGAGATTACACAGAGGACGCACAAATTTTGGTCAAGGCAGCTTCAATAATAAGAAAATACATTTTCAGCCACGAGGCATATAAATTTAATGGATCGTTTTCAGAAAATAGTCAAGAAGCGTTGTTACCATCTAACCTCAAAACCTCAATATTCTTACTTTTTAATGGAGACGGTTTGAAAAAGCAAGATAAGCACGAGTCCCAAGCATGCCTTACCATTGGCCAGCCTATTGTCTACAACACTAAGAACAAAATCAAAAGAACCCGATACAGAAACAAGGCACTTTTAGGAGCGGTCACACAGCTTGACGAGTGGATTGCAGAAGCCATGTGCGAGCACTTTGACGAAGACGGATTTGTATCCCCTGCCTGCCTGCTAAAGGAGAAAGGACAGGCATTTAAAGAGGAAACAGAAACACTTGCCTATTTAGCCTCCAATCCGATTGAGTCCCTTGATGCAGACTCAGTAGCAGTAGCAGTAGCAGTAGCAGTAGTAGTGGTAGTAGCAGTAGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGTAGTGGATAAAATAGCATTCAATATATTCCCATGTCTCCTTCGACTTCAGTTTTCTGAAGATAATTTCAGTTCGGGAAAAAGAAAGACGAAGGTTCGTGGAAGATCACCGCGAAATTCCTCTCAACTACTCATGAAGATTGGGGATAAGATGGTTACGTACACTGCTTTCAACGATGCTATTCAGAGCTTCTTAACCAATATCAAGTGTGACACCGCCGTAATCGTGGACTTTGTGCGGATTCTGAACACTTTACAAAGCAAAATGGTGGAATACAAGTTGATAAAATTTGACCACGACAACGAAAAGGTCTACGGCAATATAAGAGCCAAGGAAATTATTGACGTTTTGCAAGCTCAGGAATTAAAGAATCCCAGCACCAGTATAGCTGATTGGAGACCTGAGTATTGCAGTTATGTTGTGGAAGGATCACCTGGCCAGCCATTAGGAGAATGCATGAGATATTTCAACACGGTCGAAGCAAATATGAGACTAAGACGCAAGAAAATTCAGGAAAGCCTGACGGAGCCAGGAGAAACTGTTCAAACAATCGTCGCCCATCCCAGATTAGGATGTCCAGAATTTCTCTATCCAAGTTGCGAGCCTACTCCAGTCGGAGGGTTATCCTGTTCTCTGTTCTTTCCTGATCAGGGTATTTTCCAAGCTCATCCACGATTCAGCACACTGACAAGAAACATTCGAGAAAGAAGGGGTTCAAAGGTTGTCATCAATATTCCGATTTTCAAAGATGTGAAAACTTCATCACCCTTCATTGAAACATTTCCTGACGTTGATGAAGAAAGTACTAGAGCGGCGCTGCCAGATCATATCTACATGGACGCCGTTGGTTGTGGAATGGTAATGTGCTGCCTTCAGGCGACTGTCCAGGCTTGTAACATCAGCGAAGCAAGGTTTCTGTATGATCAACTGTCAGCGATCAGTCCGATAGTGATGGCTCTGTCTGCAGGCACTCCCATAATTCGTGGATACCTGGCAGATACGGATTGCCGTTGGAGTGTGATATCTGCGGCAATGGATGATCGAACTCTTGAGGAGAGAGGACTTGAGCCTTTGAAGGAAAATAAATTTGTCATTCCAAAATCACGATTTGACTCAATCAGTACATACCTGTCTCCTGAGGGAAAGATGTACAACGACATTGAATTAGTCTATGACAAGGAGATTTGTCAACAGCTCATGGATGCTGGTATGGACGAACAACTAGCCCGCCATTTCGCTCACTTATTCATCAGAGATCCTGTGACATTGTTTCGTGAACACATAAATGAAGACGACGAGCACAACTCGAATCACTTTGAGAACATCCAGTCCACCAACTGGCAGAACATGCGATTTAAACCGCCGCCTAGTCCTAACTCTTCCATCGGATGGAGAGTCGAGTTCAGACCCGCAGATGTGCAGTTAACAGACTTCGAAAATGCCGCCTACGTGACATTCGCTGTGCTTCTCACGAGAGTCATTTTGTCGATGGACCTTAACCTACTTATTCCGTTATCCAAGGTGGATACGAACATAGACAAAGCCCAGAAGAGAGATGCTGTCCGCCAGGAACATTTTTACTTTAGGAAGACATTGAAGAAAAGTTTCCTTGCAAACAACTGCAACGAGGACCCTGACGAGGAATTTGAGCTGATGACGATAGACAAGATAATCAACGGCAAGGATGATGAATTTCCAGGCCTGATACCGCTGATCGAAAGATACTTGGCGACCGTTGATGTTGACATTGACACGCATTGTACCATTTCCCAATACTTGAAACTGATCTCGAAAAGGGCTTCTGGTGAATTCCTGACAACAGCACAGTGGATTCGCGGGTTGGTGGAAGCACATCCTGACTACAAAAAGGACTCCATTGTTAGTGAAACGATCTGTTATGATTTGTTAAATATTACTGATCGTGTTGGTCGGGGAGAAATTGGAGCCCCTGGTCTCTTAGGAAACCTGACGTCGAGGACAAGTGACAGTCTTCTAAAGAAATGCACAGAAACAAACAAGAAGATGAAAGAAATGAGAAGCTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P48506	Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens OX=9606 GN=GCLC PE=1 SV=2
P97494	Glutamate--cysteine ligase catalytic subunit OS=Mus musculus OX=10090 GN=Gclc PE=1 SV=4
P19468	Glutamate--cysteine ligase catalytic subunit OS=Rattus norvegicus OX=10116 GN=Gclc PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001812 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03074 all species →	GCS	Glutamate-cysteine ligase	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR014746 all species →	Homologous_superfamily	Glutamine synthetase/guanido kinase, catalytic domain	Interproscan
IPR004308 all species →	Family	Glutamate-cysteine ligase catalytic subunit	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11164 all species →	GLUTAMATE CYSTEINE LIGASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0004357 all species →	Molecular Function	glutamate-cysteine ligase activity	Interproscan
GO:0006750 all species →	Biological Process	glutathione biosynthetic process	Interproscan
GO:0017109 all species →	Cellular Component	glutamate-cysteine ligase complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11204	GCLC; glutamate--cysteine ligase catalytic subunit	EC:6.3.2.2	Longevity regulating pathway - worm	ko04212	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.