Detailed information of evm.model.Ap3.249 in Astrangia poculata

Genomic Location: Ap3:2446303...2460903
NR annotation: XP_020622379.1, acetoacetyl-CoA synthetase-like [Orbicella faveolata]
Species Astrangia poculata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q5ZLG0Acetoacetyl-CoA synthetase OS=Gallus gallus OX=9031 GN=AACS PE=2 SV=1
A3QK15Acetoacetyl-CoA synthetase OS=Danio rerio OX=7955 GN=aacs PE=2 SV=1
Q9D2R0Acetoacetyl-CoA synthetase OS=Mus musculus OX=10090 GN=Aacs PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003893 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00501
all species →
AMP-bindingAMP-binding enzymeFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR045851
all species →
Homologous_superfamilyAMP-binding enzyme, C-terminal domain superfamilyInterproscan
IPR042099
all species →
Homologous_superfamilyANL, N-terminal domainInterproscan
IPR020845
all species →
Conserved_siteAMP-binding, conserved siteInterproscan
IPR000873
all species →
DomainAMP-dependent synthetase/ligase domainInterproscan
IPR005914
all species →
FamilyAcetoacetyl-CoA synthaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR42921
all species →
ACETOACETYL-COA SYNTHETASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0006629
all species →
Biological Processlipid metabolic processInterproscan
GO:0030729
all species →
Molecular Functionacetoacetate-CoA ligase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01907AACS, acsA; acetoacetyl-CoA synthetaseEC:6.2.1.16
Lipid biosynthesis proteinsko01004deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of evm.model.Ap3.249 across 49 RNA-seq samples of Astrangia poculata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

49Samples
0TPM > 0
4Conditions
0.0Max TPM
0.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organism · cold control 14 0 0.00 0.00
whole organism · heat control 12 0 0.00 0.00
whole organism · cold challenge 12 0 0.00 0.00
whole organism · heat challenge 11 0 0.00 0.00

Per sample · hover a bar for the full sample record

Show the sample table (49 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR10674714 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674715 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674724 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674733 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674734 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674735 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674736 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674737 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674739 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674743 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674746 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674747 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674748 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674750 whole organism · cold control whole organism not recorded cold control SRP237293 0.00
SRR10674706 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674707 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674708 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674717 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674718 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674720 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674721 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674725 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674731 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674741 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674752 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674753 whole organism · heat control whole organism not recorded heat control SRP237293 0.00
SRR10674711 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674712 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674713 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674722 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674723 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674730 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674732 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674738 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674740 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674744 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674745 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674749 whole organism · cold challenge whole organism not recorded cold challenge SRP237293 0.00
SRR10674709 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674710 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674716 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674719 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674726 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674727 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674728 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674729 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674742 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674751 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00
SRR10674754 whole organism · heat challenge whole organism not recorded heat challenge SRP237293 0.00

Source: CnidoSite RNA-seq expression matrices (APOCU_TPM, StringTie quantification over 49 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Astrangia poculata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated0not in this network-
Negatively correlated0not in this network-

This gene has no edge at all in the Astrangia poculata network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Astrangia poculata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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