Gene detail

Detailed information of evm.model.Ap4.7283 in Astrangia poculata

Genomic Location: Ap4:57660255...57671989
NR annotation: XP_020631317.1, NEDD8-activating enzyme E1 catalytic subunit-like isoform X1 [Orbicella faveolata]
Species abbreviation APOCU · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5R4A0	NEDD8-activating enzyme E1 catalytic subunit OS=Pongo abelii OX=9601 GN=UBA3 PE=2 SV=2
Q8TBC4	NEDD8-activating enzyme E1 catalytic subunit OS=Homo sapiens OX=9606 GN=UBA3 PE=1 SV=2
Q7ZVX6	NEDD8-activating enzyme E1 catalytic subunit OS=Danio rerio OX=7955 GN=uba3 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004430 (this species only)
Ubiquitin family	E1\|ThiF\|ThiF · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08825 all species →	E2_bind	E2 binding domain	Domain	Interproscan
PF00899 all species →	ThiF	ThiF family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR014929 all species →	Domain	E2 binding	Interproscan
IPR000594 all species →	Domain	THIF-type NAD/FAD binding fold	Interproscan
IPR035985 all species →	Homologous_superfamily	Ubiquitin-activating enzyme	Interproscan
IPR045886 all species →	Family	ThiF/MoeB/HesA family	Interproscan
IPR030468 all species →	Domain	NEDD8-activating enzyme E1 catalytic subunit, N-terminal domain	Interproscan
IPR033127 all species →	Active_site	Ubiquitin-activating enzyme E1, Cys active site	Interproscan
IPR023318 all species →	Homologous_superfamily	Ubiquitin activating enzyme, alpha domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10953 all species →	UBIQUITIN-ACTIVATING ENZYME E1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0019781 all species →	Molecular Function	NEDD8 activating enzyme activity	Interproscan
GO:0045116 all species →	Biological Process	protein neddylation	Interproscan
GO:0008641 all species →	Molecular Function	ubiquitin-like modifier activating enzyme activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0032446 all species →	Biological Process	protein modification by small protein conjugation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10686	UBA3, UBE1C; NEDD8-activating enzyme E1	EC:6.2.1.64	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.