Gene detail

Detailed information of evm.model.Ap5.1452 in Astrangia poculata

Genomic Location: Ap5:15517560...15532162
NR annotation: XP_020617647.1, cGMP-dependent 3',5'-cyclic phosphodiesterase-like [Orbicella faveolata]
Species abbreviation APOCU · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

evm.model.Ap5.1452

GGACCTTTGTCACGCAAAATAGGCGAATTTCTTCAAACACAGACCAATGCTGAAGGCAGTGCAATTCTTATACTAGATCACACAGCAGGGGAACTTCACAACAAGCAAGAAAGCAGAGATCACATGGACGAGAAGAGAATTGAGGTTTCTGGAAGCGTTTTTGAGGATGTCATTGAATCTAGAAGAAAATTAAATGTTTGTAATATAGAAAAGGACACAAAGTACAGATACGATTTACAGAGAATAACAGATTGTTATGTTCAGTCAATGCTGTGTGTTCCAATAGTCAGCCTCAAGACAGGGGGTGTTATAGCTGTAGCGTGTGTTTTCAACAAAAATCTTCCTGAAAAAAGGTTTTCCTCCTTTGACGAAGAAAATGTCTGCTTTTGCTGCGAGAATATTGCGGCAAATGTAGAACACACTTTAGAATGGGAAAGAGAAATGGTGATTAAAAGGCAACAAGAGCATTTACTAAAGGTTGCCAAGAACCTGTTTACTCTTGTAGATGATGTAAGTGTCTTACTAAGTGAAATCATGACAGAGGCCCGCAATTTGACTAATGCTGAAAGGTGTTCCTTATTTCTGTGGGACAAAGAAAGAGATGAACTTGTTGCAAAGGTGTTTGATGGAGAAATTCCTTCAGATGGAGACAAGGGAAAGGAACCAGAAGTAAGAATTCCTGTTACACAAGGAATAGTGGGACATGTTGCCACAACAGGAAAGATGCTCAATATAAAAGACGCATATGGTCATCCATTGTTCTATAAAGGTCTCGATGAGAAAACCGGCTTCAGAACAAGAAATATATTGTGCTTTCCAATTAAAGATGAAGAGGAGGTGATTGGAGTAGCCCAGTTATGCAACAAGACAAACGGTTCTTGTTTCACAAAGTTTGACGAAGACCTCACCAGTGCATTTGCCATCTACTGTGGTGTGAGCATTTTCCATTCACTTTTGTACAAGAATGCCACAGATGCCTCTTTCAGAAGTCGACTGTCAAGCGAAATGATGATATATCACATGACGGTCACCCAAGCTGAAGTGAATCCCCTAGTTAATAAACCGATTTGCACCACAGAAGAAATACACCCACAATTTACTCTTTTCACGTGTGCGCCGAGAACCATTATCCCCGATGCCACCATTCCGGCCTGTCTTTGCATGTTTGAAGACCTTGGAATGATAGAGAAATGGAAAATTCCCCGAGAAGTAATAGTGAGGTTCTCATTGATGGTTAGAAAAGGTTACAGAAACCCTCCTTATCACAATTGGAGTCACGCATTTACCGTTGCACACTTCTGTTACCTTCTGTACAAGAATGCAAAGATTAGCAGTTACTTAAGAGACATTGAAATGTTGGCATTGTTCGTGGCCTGCCTGTGCCATGATATCGACCACAGGGGCACCACAAATTCCTTTCAGGTTTCCTCAGGTTCCACGCTTGCGGCGCTGTATAGTTCAAAAGGATCTGTGTTGGAGAGGCACCATTTTGCTCAGACCATGTGTATACTCAATTCAGAAGGATGTAACATTTTCAAAAATTTAACCGGCAAGGACTTTGAGGAAGTGACCGTTCTTGTACGGGACATCATCCTAGCCACAGACCTCGCCCATCACTTAAGAATCCTTCAAGACATTAAAAAGATGGCAGAAGATGGTTTTAATCGTAATTCCAAGGATCATCAAACTCTCCTCCTCTTTCTCATGATGACGGCCAGTGATTTGTCGGATCAGACCAAGAATTGGGAGGGGACGAGAAGAACAGCGGACCTAATATATACGGAATTCTTTTCGCAAGGCGATAAGGAAAAGCACATGGGAATAACTCCGATGGAAATGATGGACAGAGAACGAGCGTGTATTCCTAAACTTCAAATCGACTTCTTAGATGCAATCGCACTTCCTGTATACAGGCTGTTGTCTTCACTGCTGCCAGAGACTCAAGTTGTTTTAGACACAGTTCTGTCCAACAGAGAGAAGTGGCAGAAAGCACAGGAAGATGGCGACTATGTGTACAGACCTGTGGCCACAGGCGACAGAGAAATTCACATGGCAAAGAATGGAATGCCTTCATCATAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q922S4	cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Mus musculus OX=10090 GN=Pde2a PE=1 SV=4
O00408	cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Homo sapiens OX=9606 GN=PDE2A PE=1 SV=1
Q01062	cGMP-dependent 3',5'-cyclic phosphodiesterase OS=Rattus norvegicus OX=10116 GN=Pde2a PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002981 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00233 all species →	PDEase_I	3'5'-cyclic nucleotide phosphodiesterase	Domain	Interproscan
PF01590 all species →	GAF	GAF domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR023174 all species →	Conserved_site	3'5'-cyclic nucleotide phosphodiesterase, conserved site	Interproscan
IPR003018 all species →	Domain	GAF domain	Interproscan
IPR002073 all species →	Domain	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	Interproscan
IPR023088 all species →	Family	3'5'-cyclic nucleotide phosphodiesterase	Interproscan
IPR029016 all species →	Homologous_superfamily	GAF-like domain superfamily	Interproscan
IPR003607 all species →	Domain	HD/PDEase domain	Interproscan
IPR036971 all species →	Homologous_superfamily	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11347 all species →	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004114 all species →	Molecular Function	3',5'-cyclic-nucleotide phosphodiesterase activity	Interproscan
GO:0004115 all species →	Molecular Function	3',5'-cyclic-AMP phosphodiesterase activity	Interproscan
GO:0004118 all species →	Molecular Function	3',5'-cGMP-stimulated cyclic-nucleotide phosphodiesterase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005741 all species →	Cellular Component	mitochondrial outer membrane	Interproscan
GO:0005743 all species →	Cellular Component	mitochondrial inner membrane	Interproscan
GO:0005759 all species →	Cellular Component	mitochondrial matrix	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0010628 all species →	Biological Process	positive regulation of gene expression	Interproscan
GO:0010754 all species →	Biological Process	negative regulation of cGMP-mediated signaling	Interproscan
GO:0010821 all species →	Biological Process	regulation of mitochondrion organization	Interproscan
GO:0019933 all species →	Biological Process	cAMP-mediated signaling	Interproscan
GO:0019934 all species →	Biological Process	cGMP-mediated signaling	Interproscan
GO:0042803 all species →	Molecular Function	protein homodimerization activity	Interproscan
GO:0043951 all species →	Biological Process	negative regulation of cAMP-mediated signaling	Interproscan
GO:0046069 all species →	Biological Process	cGMP catabolic process	Interproscan
GO:0047555 all species →	Molecular Function	3',5'-cyclic-GMP phosphodiesterase activity	Interproscan
GO:0048471 all species →	Cellular Component	perinuclear region of cytoplasm	Interproscan
GO:0097060 all species →	Cellular Component	synaptic membrane	Interproscan
GO:0008081 all species →	Molecular Function	phosphoric diester hydrolase activity	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K18283	PDE2A; cGMP-dependent 3',5'-cyclic phosphodiesterase	EC:3.1.4.17	Morphine addiction	ko05032	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.