Gene detail

Detailed information of evm.model.Ap6.930 in Astrangia poculata

Genomic Location: Ap6:8905411...8920469
NR annotation: XP_022793222.1, phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like [Stylophora pistillata]
Species abbreviation APOCU · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap6.930

gactacgtgttgaagattgttggacaagagagctatttactcggaaattattcgttattgcagtacacgtacattcgtacgtgtgtttccaagggtgtcagaccaatgctctctcttgtacttcgttcctcccttcaagttgaggtacttgatgttagcgggataagtcgcagatttcaaggaggggcagcccccccactacctcaaaagccacagtcagcaagcttgtcactgtgggatattgagacccacgtgcgactcaaggtgctttctgcagctaatgtgaatgcaggtgacttgatgaaggtttgtgtcagagcaggtatttaccatggtggagacgcactgtgtgacatcacaagcacaagaccagagagtggatcaaatccaacctggaaccagttcatagactttgatttaaacatgattgacattcctcgcatggctcgcctctgtctagttatttatggtgtttatggtgccacaaagaaatcgaaaaaaaaagtaaaagaggaaaccattcctgttgcatgggtcaacacaaccctgtttgattatcaaggaaagttacggcagggtcctttgaagctctttgcgtggcctgtacctgaaacaatggctgatcaactcaatccagttggcactgtagtctccaacatcaacactgctacctctgtatcactcaacattgagtttccaagttactctcatgctgttgtgtatccatcatttgatacggttgctgaactagctgcaaaagttactgatgccaatatttttggaggagcagatccatctttgcttgagcaactgaggcagattgtaaaccgtgaacctttggccccaatctttgaacaagaaaaggagctggtttgggagcggagaatcgactgccgagaacattttccgcatgctttagctaaactgttgtgctgtgtgaaatggaacagcaataaagacgttgcgttgatgcaaattctgcttcaaacatggcccaggctagagccagaacaggctttagaacttttggattacacatatgctgaccaagaagtcaggaagattgctgtgcagtgtattgaaaaaatgagtgatagtgaaatttcacagtaccttcttcagctagtgcaggttgtgaagtatgaatcataccatgacaatgacttggcggagtttttactgagaagagctctgaagaatcagcactttggacatcaattgttttggtttctcagagctgaaatggagaaccctgaggtctcagtgaggtttggtctgatgttagaggcttattgtcgtggtgcgccatcacacatgaaaagcctgcagcgccaggcccaggctctaagcaagatgaaggctgtgactgagttacttcaacttatagacagagacaaaaaggagaaaggtttggaaacaatgaaagaacttcttcgtcagaaaacctatcagggagcactatctaaagtcaactctcctctaaatccaatctacaagctgcgaaatttgaatgttgaacattgcaagtttatggattccaaaatgagaccactatacttagtgtttgaaaatttggatgagcttggagaccttgtacgcattatcttcaagaatggtgatgatctccgtcaggacatgttaacgttacaacttttcaaaatcatggacaggatttggcaaaatgaaggcctggatttaggaatgatcccgtatggctgtttgtccactggcagctcgattggaatgatcgaggttgtccatgatgccgagactatcgccaagctacagaaaactaaaggagtcactgcaacctttgctaaaaactgtatctgggattggctaaaggagtaccatgccaatgaagaaagtttattagaagctgtgcggcgtttcacgctctcctgtgcagggtactgtgtggcaacgtatgttctgggggtgggtgacaggcatagtgacaacattatggtgaagaaaactgggcagttgttccacattgatttcggccacattctgggaaactttaagagcaagtttggagttcggagagaaagggtgccttttgtgctcaccgatcattttgtgcacgtaatttctctcggcaaaggaaaagaaacagttgaatttgaaagatttaaacagctctgtgaagaagcttttctgattctgcgccgtaagggcccacttctgatcaacctgtttgtcatgatgttgtccgctggtctccctgaactgcggtcacttgacgacatcggctacttgcggaagacactggtactgtctctctcggaagaagacgccatcaaagattttaggaagaagttcgatcatgctatcaacaacagcttttcaacgtcaatgaactggttcgcgcacaacgtaaaaagagataacccttga

Transcript

evm.model.Ap6.930

GACTACGTGTTGAAGATTGTTGGACAAGAGAGCTATTTACTCGGAAATTATTCGTTATTGCAGTACACGTACATTCGTACGTGTGTTTCCAAGGGTGTCAGACCAATGCTCTCTCTTGTACTTCGTTCCTCCCTTCAAGTTGAGGTACTTGATGTTAGCGGGATAAGTCGCAGATTTCAAGGAGGGGCAGCCCCCCCACTACCTCAAAAGCCACAGTCAGCAAGCTTGTCACTGTGGGATATTGAGACCCACGTGCGACTCAAGGTGCTTTCTGCAGCTAATGTGAATGCAGGTGACTTGATGAAGGTTTGTGTCAGAGCAGGTATTTACCATGGTGGAGACGCACTGTGTGACATCACAAGCACAAGACCAGAGAGTGGATCAAATCCAACCTGGAACCAGTTCATAGACTTTGATTTAAACATGATTGACATTCCTCGCATGGCTCGCCTCTGTCTAGTTATTTATGGTGTTTATGGTGCCACAAAGAAATCGAAAAAAAAAGTAAAAGAGGAAACCATTCCTGTTGCATGGGTCAACACAACCCTGTTTGATTATCAAGGAAAGTTACGGCAGGGTCCTTTGAAGCTCTTTGCGTGGCCTGTACCTGAAACAATGGCTGATCAACTCAATCCAGTTGGCACTGTAGTCTCCAACATCAACACTGCTACCTCTGTATCACTCAACATTGAGTTTCCAAGTTACTCTCATGCTGTTGTGTATCCATCATTTGATACGGTTGCTGAACTAGCTGCAAAAGTTACTGATGCCAATATTTTTGGAGGAGCAGATCCATCTTTGCTTGAGCAACTGAGGCAGATTGTAAACCGTGAACCTTTGGCCCCAATCTTTGAACAAGAAAAGGAGCTGGTTTGGGAGCGGAGAATCGACTGCCGAGAACATTTTCCGCATGCTTTAGCTAAACTGTTGTGCTGTGTGAAATGGAACAGCAATAAAGACGTTGCGTTGATGCAAATTCTGCTTCAAACATGGCCCAGGCTAGAGCCAGAACAGGCTTTAGAACTTTTGGATTACACATATGCTGACCAAGAAGTCAGGAAGATTGCTGTGCAGTGTATTGAAAAAATGAGTGATAGTGAAATTTCACAGTACCTTCTTCAGCTAGTGCAGGTTGTGAAGTATGAATCATACCATGACAATGACTTGGCGGAGTTTTTACTGAGAAGAGCTCTGAAGAATCAGCACTTTGGACATCAATTGTTTTGGTTTCTCAGAGCTGAAATGGAGAACCCTGAGGTCTCAGTGAGGTTTGGTCTGATGTTAGAGGCTTATTGTCGTGGTGCGCCATCACACATGAAAAGCCTGCAGCGCCAGGCCCAGGCTCTAAGCAAGATGAAGGCTGTGACTGAGTTACTTCAACTTATAGACAGAGACAAAAAGGAGAAAGGTTTGGAAACAATGAAAGAACTTCTTCGTCAGAAAACCTATCAGGGAGCACTATCTAAAGTCAACTCTCCTCTAAATCCAATCTACAAGCTGCGAAATTTGAATGTTGAACATTGCAAGTTTATGGATTCCAAAATGAGACCACTATACTTAGTGTTTGAAAATTTGGATGAGCTTGGAGACCTTGTACGCATTATCTTCAAGAATGGTGATGATCTCCGTCAGGACATGTTAACGTTACAACTTTTCAAAATCATGGACAGGATTTGGCAAAATGAAGGCCTGGATTTAGGAATGATCCCGTATGGCTGTTTGTCCACTGGCAGCTCGATTGGAATGATCGAGGTTGTCCATGATGCCGAGACTATCGCCAAGCTACAGAAAACTAAAGGAGTCACTGCAACCTTTGCTAAAAACTGTATCTGGGATTGGCTAAAGGAGTACCATGCCAATGAAGAAAGTTTATTAGAAGCTGTGCGGCGTTTCACGCTCTCCTGTGCAGGGTACTGTGTGGCAACGTATGTTCTGGGGGTGGGTGACAGGCATAGTGACAACATTATGGTGAAGAAAACTGGGCAGTTGTTCCACATTGATTTCGGCCACATTCTGGGAAACTTTAAGAGCAAGTTTGGAGTTCGGAGAGAAAGGGTGCCTTTTGTGCTCACCGATCATTTTGTGCACGTAATTTCTCTCGGCAAAGGAAAAGAAACAGTTGAATTTGAAAGATTTAAACAGCTCTGTGAAGAAGCTTTTCTGATTCTGCGCCGTAAGGGCCCACTTCTGATCAACCTGTTTGTCATGATGTTGTCCGCTGGTCTCCCTGAACTGCGGTCACTTGACGACATCGGCTACTTGCGGAAGACACTGGTACTGTCTCTCTCGGAAGAAGACGCCATCAAAGATTTTAGGAAGAAGTTCGATCATGCTATCAACAACAGCTTTTCAACGTCAATGAACTGGTTCGCGCACAACGTAAAAAGAGATAACCCTTGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8BTI9	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Mus musculus OX=10090 GN=Pik3cb PE=1 SV=2
Q9Z1L0	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Rattus norvegicus OX=10116 GN=Pik3cb PE=2 SV=1
P42338	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PIK3CB PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002467 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00794 all species →	PI3K_rbd	PI3-kinase family, ras-binding domain	Domain	Interproscan
PF00613 all species →	PI3Ka	Phosphoinositide 3-kinase family, accessory domain (PIK domain)	Repeat	Interproscan
PF00454 all species →	PI3_PI4_kinase	Phosphatidylinositol 3- and 4-kinase	Family	Interproscan
PF00792 all species →	PI3K_C2	Phosphoinositide 3-kinase C2	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR015433 all species →	Family	Phosphatidylinositol kinase	Interproscan
IPR016024 all species →	Homologous_superfamily	Armadillo-type fold	Interproscan
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR018936 all species →	Conserved_site	Phosphatidylinositol 3/4-kinase, conserved site	Interproscan
IPR000403 all species →	Domain	Phosphatidylinositol 3-/4-kinase, catalytic domain	Interproscan
IPR036940 all species →	Homologous_superfamily	Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily	Interproscan
IPR002420 all species →	Domain	C2 phosphatidylinositol 3-kinase-type domain	Interproscan
IPR001263 all species →	Domain	Phosphoinositide 3-kinase, accessory (PIK) domain	Interproscan
IPR042236 all species →	Homologous_superfamily	Phosphoinositide 3-kinase, accessory (PIK) domain superfamily	Interproscan
IPR000341 all species →	Domain	Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan
IPR008290 all species →	Family	Phosphatidylinositol 3-kinase, Vps34 type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10048 all species →	PHOSPHATIDYLINOSITOL KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0005942 all species →	Cellular Component	phosphatidylinositol 3-kinase complex	Interproscan
GO:0014065 all species →	Biological Process	obsolete phosphatidylinositol 3-kinase signaling	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016303 all species →	Molecular Function	1-phosphatidylinositol-3-kinase activity	Interproscan
GO:0016477 all species →	Biological Process	cell migration	Interproscan
GO:0035005 all species →	Molecular Function	1-phosphatidylinositol-4-phosphate 3-kinase activity	Interproscan
GO:0036092 all species →	Biological Process	phosphatidylinositol-3-phosphate biosynthetic process	Interproscan
GO:0046854 all species →	Biological Process	phosphatidylinositol phosphate biosynthetic process	Interproscan
GO:0048015 all species →	Biological Process	phosphatidylinositol-mediated signaling	Interproscan
GO:0052742 all species →	Molecular Function	phosphatidylinositol kinase activity	Interproscan
GO:0016301 all species →	Molecular Function	kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00922	PIK3CA_B_D; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta	EC:2.7.1.153	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.