Gene detail

Detailed information of evm.model.Ap7.544 in Astrangia poculata

Genomic Location: Ap7:6501777...6514076
NR annotation: CAH3130523.1, unnamed protein product [Pocillopora meandrina]
Species abbreviation APOCU · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8CHM7	2-hydroxyacyl-CoA lyase 1 OS=Rattus norvegicus OX=10116 GN=Hacl1 PE=1 SV=1
Q9QXE0	2-hydroxyacyl-CoA lyase 1 OS=Mus musculus OX=10090 GN=Hacl1 PE=1 SV=2
Q9UJ83	2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003527 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02775 all species →	TPP_enzyme_C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	Domain	Interproscan
PF00205 all species →	TPP_enzyme_M	Thiamine pyrophosphate enzyme, central domain	Domain	Interproscan
PF02776 all species →	TPP_enzyme_N	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR045025 all species →	Family	TPP-binding domain containing protein HACL1-like	Interproscan
IPR029035 all species →	Homologous_superfamily	DHS-like NAD/FAD-binding domain superfamily	Interproscan
IPR011766 all species →	Domain	Thiamine pyrophosphate enzyme, TPP-binding	Interproscan
IPR012000 all species →	Domain	Thiamine pyrophosphate enzyme, central domain	Interproscan
IPR029061 all species →	Homologous_superfamily	Thiamin diphosphate-binding fold	Interproscan
IPR012001 all species →	Domain	Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43710 all species →	2-HYDROXYACYL-COA LYASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0001561 all species →	Biological Process	fatty acid alpha-oxidation	Interproscan
GO:0005777 all species →	Cellular Component	peroxisome	Interproscan
GO:0030976 all species →	Molecular Function	thiamine pyrophosphate binding	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0000287 all species →	Molecular Function	magnesium ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K12261	HACL1; 2-hydroxyacyl-CoA lyase	EC:4.1.2.63	Peroxisome	ko04146	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.