Gene detail

Detailed information of evm.model.Ap8.176 in Astrangia poculata

Genomic Location: Ap8:1697801...1719047
NR annotation: XP_020603235.1, guanine nucleotide exchange factor DBS-like [Orbicella faveolata]
Species abbreviation APOCU · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap8.176

gcacaagctaagaatgaatgcttgtttgtcacgatacctgatcaccccaagtttggaagccttagtgacagagatgctgaaagggtttttaagtatcttgttggactggccagtgaagagctgctcaagaaaggatttattttggtcctcgacaggagaaaagacaaatgggcagctgttaaatcttgtcttcaaaaaattcagaaatgcttcccagctagagtaggtaacatacatgtcatttatgtgttaaagccacaaggattttttcaaaagtatggttctaaaccaagctttgtggctggtggcctgcttggtgactcaaaaataaagatcgtcactcttaattctgctgctgagttagaggagttcattgataaatcacagctgacagaagaactgggagggaccctgcaatataaacatgcacaatgggttcaatacagaacggcaattgaaagatttgaacggaacttaacgcactttgatgagaggattgcagagctgcggcagacttttttaaaaacaaaactgtcttcaagtatacaggaattggaacatattattgaaacacaagaggaaatgtggcatgacgtcaaagaagacatgggaagtgcgagacaagctggagttacactgttggactgtattcatcctaagcacagagaaggccatgacgagtggtatactcctgatgtcctggcaaatgctgttgagttgaaacaatcgctgattcaacttgaggaaatggaaaacaattttgaaaggttttggagagaacacaagttaaagattcagtatggattgagagtgtgtctctttgagcgggagatgagccagacaacaggccttcttctgtcagcgttaggtaatctatcagccatgacagatcttggggactcaaaagatgatgcacaatcattattagatcaacttaaagaatttacagataagtctgtggaactccttaacaaagccaaaggtttagttgtcaaggggctcaaaatgatagagtctaatgaacaatccaaagactccatcaagatgaaatgtgatgaaataagggagctctgcgacaagtttgacaagggggcacaaaagagagaagatgatttaaacaaagcaatggatatccatgagtgcctggaaatggtcaataagtggtgtaagacgggtgtagatcttttagcattacagcccatagaaagatttaagtcgtcagagggtgcagagaaagcactggatgaaattgataactttttgaaaagtccacaagggatgaacatggtcaaggtcaggaaaatgacgcccacaagtaacgcccttggtaacaagacactgattactaaggtcaaggatagcatgaagagaatcggcgaggtcaatgatatgatggccaaacgtgaaaccagcctgaaaaaacttgttgtgaagcgtccagtccagccagtaccagcaatacctgccaatcaagcttccactcctgaagatcaaaaagattctaaagtccgtaaacccagtacagctatcaaaagtccagttcagttccgaagggagcgtaagaagtcaactcccccagccagcactgtatcgccaaagcgaccagtgtccattgtgttgacagacactcttcaggtgcaaggaggtgtgcgcactacagtttctgagccaagtatgcagagagatattgtggatggcactgacagcccagaagctggtaagaaacggctacaagtgatgagagaattgattacaacagaggaaatttacgtccatgacttggagtgcattgtcaatggatacctaaaggaatttgcacaagctggagacaagattcctgctgatttacgtggcaagaaaagcatcatattcggaaatattgaccagatctatgaatttcataaaaatgactttttacttgagcttgaggcatgtgaggataaaccctctcttgtgggcgcagccttcatcatgaagagcagagaatttgaaatgtatgcaacatattgtaagaacaaaccaaattctgaagcactaagaatggactacattaatttgcctttcttcaaggagtgtcaagagcacttgggtcatttgctgcctttaagtgcattccttctaaaaccagtgcagagaatcacaaaataccaactactgttgagggagatgatgaaactaacactaagaaacagtactgcatatgatgacctagagaaagctcttgaaaccatggaaggagttttacgccatgtgaatgatgttatgcactcttgcggtataagaggattccgtgggaaccttgctgagcagggaaagttgcttcttcaagatgcctttatggtttgggaaacaaacaaaaccctgcacagtataagtttgttgccacttaaaggaggaaagcagcgtcaagtgtttttgtatgaaaagatgatcatcttcagcaagaagattgatgttcaagagacaagcaaagatgctgttgtgtatgaatacaagaaagatgttaagacatgtgatgtgggattcactgaaacagtacaagacgcacctgaaaagtttgaactatggctgaatggaagatcaggagtgttcatcatgcaacctacatcggtggaagttaagaaacgttgggcaagggaaataacaaatcttctgcattctcaatttagccaactgagagagcaatttggtattcatgatcgttggaagtcgacctcagctctgtcgtcagcaactacttcagaaacaccactgcgaacaagaagccagtctacattgtcaattggctccactgttgctgctggcaacaacaggtgttcaaacatatatgagggaaatactaccaatgacgacgatgacgatggctttgacacggaagaatttgactcagacagtgatgagtctcctaccaatgaaccagtgcagactgaatgcaatacacagtatactacacagcctgcgaatataacagagtatgacaatcaagaacttccacagaaaggatcaagatactatgctattgctggctatgatgcagtggaaaacacagaggtttccttccaagaaggcgacactctggaactgttgagagttggacaggacggatggtggtttgcacggaacacaggaactgctcaggagggatgggttcctgcaagttatttgacatttcaaggaatggcacaatga

Transcript

evm.model.Ap8.176

GAGCACAAGCTAAGAATGAATGCTTGTTTGTCACGATACCTGATCACCCCAAGTTTGGAAGCCTTAGTGACAGAGATGCTGAAAGGGTTTTTAAGTATCTTGTTGGACTGGCCAGTGAAGAGCTGCTCAAGAAAGGATTTATTTTGGTCCTCGACAGGAGAAAAGACAAATGGGCAGCTGTTAAATCTTGTCTTCAAAAAATTCAGAAATGCTTCCCAGCTAGAGTAGGTAACATACATGTCATTTATGTGTTAAAGCCACAAGGATTTTTTCAAAAGTATGGTTCTAAACCAAGCTTTGTGGCTGGTGGCCTGCTTGGTGACTCAAAAATAAAGATCGTCACTCTTAATTCTGCTGCTGAGTTAGAGGAGTTCATTGATAAATCACAGCTGACAGAAGAACTGGGAGGGACCCTGCAATATAAACATGCACAATGGGTTCAATACAGAACGGCAATTGAAAGATTTGAACGGAACTTAACGCACTTTGATGAGAGGATTGCAGAGCTGCGGCAGACTTTTTTAAAAACAAAACTGTCTTCAAGTATACAGGAATTGGAACATATTATTGAAACACAAGAGGAAATGTGGCATGACGTCAAAGAAGACATGGGAAGTGCGAGACAAGCTGGAGTTACACTGTTGGACTGTATTCATCCTAAGCACAGAGAAGGCCATGACGAGTGGTATACTCCTGATGTCCTGGCAAATGCTGTTGAGTTGAAACAATCGCTGATTCAACTTGAGGAAATGGAAAACAATTTTGAAAGGTTTTGGAGAGAACACAAGTTAAAGATTCAGTATGGATTGAGAGTGTGTCTCTTTGAGCGGGAGATGAGCCAGACAACAGGCCTTCTTCTGTCAGCGTTAGGTAATCTATCAGCCATGACAGATCTTGGGGACTCAAAAGATGATGCACAATCATTATTAGATCAACTTAAAGAATTTACAGATAAGTCTGTGGAACTCCTTAACAAAGCCAAAGGTTTAGTTGTCAAGGGGCTCAAAATGATAGAGTCTAATGAACAATCCAAAGACTCCATCAAGATGAAATGTGATGAAATAAGGGAGCTCTGCGACAAGTTTGACAAGGGGGCACAAAAGAGAGAAGATGATTTAAACAAAGCAATGGATATCCATGAGTGCCTGGAAATGGTCAATAAGTGGTGTAAGACGGGTGTAGATCTTTTAGCATTACAGCCCATAGAAAGATTTAAGTCGTCAGAGGGTGCAGAGAAAGCACTGGATGAAATTGATAACTTTTTGAAAAGTCCACAAGGGATGAACATGGTCAAGGTCAGGAAAATGACGCCCACAAGTAACGCCCTTGGTAACAAGACACTGATTACTAAGGTCAAGGATAGCATGAAGAGAATCGGCGAGGTCAATGATATGATGGCCAAACGTGAAACCAGCCTGAAAAAACTTGTTGTGAAGCGTCCAGTCCAGCCAGTACCAGCAATACCTGCCAATCAAGCTTCCACTCCTGAAGATCAAAAAGATTCTAAAGTCCGTAAACCCAGTACAGCTATCAAAAGTCCAGTTCAGTTCCGAAGGGAGCGTAAGAAGTCAACTCCCCCAGCCAGCACTGTATCGCCAAAGCGACCAGTGTCCATTGTGTTGACAGACACTCTTCAGGTGCAAGGAGGTGTGCGCACTACAGTTTCTGAGCCAAGTATGCAGAGAGATATTGTGGATGGCACTGACAGCCCAGAAGCTGGTAAGAAACGGCTACAAGTGATGAGAGAATTGATTACAACAGAGGAAATTTACGTCCATGACTTGGAGTGCATTGTCAATGGATACCTAAAGGAATTTGCACAAGCTGGAGACAAGATTCCTGCTGATTTACGTGGCAAGAAAAGCATCATATTCGGAAATATTGACCAGATCTATGAATTTCATAAAAATGACTTTTTACTTGAGCTTGAGGCATGTGAGGATAAACCCTCTCTTGTGGGCGCAGCCTTCATCATGAAGAGCAGAGAATTTGAAATGTATGCAACATATTGTAAGAACAAACCAAATTCTGAAGCACTAAGAATGGACTACATTAATTTGCCTTTCTTCAAGGAGTGTCAAGAGCACTTGGGTCATTTGCTGCCTTTAAGTGCATTCCTTCTAAAACCAGTGCAGAGAATCACAAAATACCAACTACTGTTGAGGGAGATGATGAAACTAACACTAAGAAACAGTACTGCATATGATGACCTAGAGAAAGCTCTTGAAACCATGGAAGGAGTTTTACGCCATGTGAATGATGTTATGCACTCTTGCGGTATAAGAGGATTCCGTGGGAACCTTGCTGAGCAGGGAAAGTTGCTTCTTCAAGATGCCTTTATGGTTTGGGAAACAAACAAAACCCTGCACAGTATAAGTTTGTTGCCACTTAAAGGAGGAAAGCAGCGTCAAGTGTTTTTGTATGAAAAGATGATCATCTTCAGCAAGAAGATTGATGTTCAAGAGACAAGCAAAGATGCTGTTGTGTATGAATACAAGAAAGATGTTAAGACATGTGATGTGGGATTCACTGAAACAGTACAAGACGCACCTGAAAAGTTTGAACTATGGCTGAATGGAAGATCAGGAGTGTTCATCATGCAACCTACATCGGTGGAAGTTAAGAAACGTTGGGCAAGGGAAATAACAAATCTTCTGCATTCTCAATTTAGCCAACTGAGAGAGCAATTTGGTATTCATGATCGTTGGAAGTCGACCTCAGCTCTGTCGTCAGCAACTACTTCAGAAACACCACTGCGAACAAGAAGCCAGTCTACATTGTCAATTGGCTCCACTGTTGCTGCTGGCAACAACAGGTGTTCAAACATATATGAGGGAAATACTACCAATGACGACGATGACGATGGCTTTGACACGGAAGAATTTGACTCAGACAGTGATGAGTCTCCTACCAATGAACCAGTGCAGACTGAATGCAATACACAGTATACTACACAGCCTGCGAATATAACAGAGTATGACAATCAAGAACTTCCACAGAAAGGATCAAGATACTATGCTATTGCTGGCTATGATGCAGTGGAAAACACAGAGGTTTCCTTCCAAGAAGGCGACACTCTGGAACTGTTGAGAGTTGGACAGGACGGATGGTGGTTTGCACGGAACACAGGAACTGCTCAGGAGGGATGGGTTCCTGCAAGTTATTTGACATTTCAAGGAATGGCACAATGA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q63406	Guanine nucleotide exchange factor DBS OS=Rattus norvegicus OX=10116 GN=Mcf2l PE=1 SV=3
Q64096	Guanine nucleotide exchange factor DBS OS=Mus musculus OX=10090 GN=Mcf2l PE=1 SV=2
O15068	Guanine nucleotide exchange factor DBS OS=Homo sapiens OX=9606 GN=MCF2L PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003120 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00018 all species →	SH3_1	SH3 domain	Domain	Interproscan
PF00621 all species →	RhoGEF	RhoGEF domain	Domain	Interproscan
PF13716 all species →	CRAL_TRIO_2	Divergent CRAL/TRIO domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011993 all species →	Homologous_superfamily	PH-like domain superfamily	Interproscan
IPR001452 all species →	Domain	SH3 domain	Interproscan
IPR001251 all species →	Domain	CRAL-TRIO lipid binding domain	Interproscan
IPR000219 all species →	Domain	Dbl homology (DH) domain	Interproscan
IPR018159 all species →	Repeat	Spectrin/alpha-actinin	Interproscan
IPR001331 all species →	Conserved_site	Guanine-nucleotide dissociation stimulator, CDC24, conserved site	Interproscan
IPR036865 all species →	Homologous_superfamily	CRAL-TRIO lipid binding domain superfamily	Interproscan
IPR001849 all species →	Domain	Pleckstrin homology domain	Interproscan
IPR035899 all species →	Homologous_superfamily	Dbl homology (DH) domain superfamily	Interproscan
IPR051336 all species →	Family	Rho GTPase-activating Guanine Nucleotide Exchange Factors	Interproscan
IPR036028 all species →	Homologous_superfamily	SH3-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22826 all species →	RHO GUANINE EXCHANGE FACTOR-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K20685	MCF2, ARHGEF14_21_22; guanine nucleotide exchange factor MCF2	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.