Genomic Location: Ap8:21288588...21308029
NR annotation: KAJ7376076.1, V-type proton ATPase catalytic subunit A [Desmophyllum pertusum]
Species Astrangia poculata · all data for this species · gene families
| CDS |
| evm.model.Ap8.1926 |
| Transcript |
| evm.model.Ap8.1926 |
| Protein |
| evm.model.Ap8.1926 |
| UniProt accession | Description |
|---|---|
| P31400 | V-type proton ATPase catalytic subunit A OS=Manduca sexta OX=7130 GN=VHAA PE=2 SV=1 |
| Q5TTG1 | V-type proton ATPase catalytic subunit A OS=Anopheles gambiae OX=7165 GN=Vha68-2 PE=3 SV=1 |
| O16109 | V-type proton ATPase catalytic subunit A OS=Aedes aegypti OX=7159 GN=VhaA PE=2 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005517 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00006 all species → | ATP-synt_ab | ATP synthase alpha/beta family, nucleotide-binding domain | Domain | Interproscan |
| PF16886 all species → | ATP-synt_ab_Xtn | ATPsynthase alpha/beta subunit N-term extension | Family | Interproscan |
| PF02874 all species → | ATP-synt_ab_N | ATP synthase alpha/beta family, beta-barrel domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR022878 all species → | Family | V-type ATP synthase catalytic alpha chain | Interproscan |
| IPR000194 all species → | Domain | ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain | Interproscan |
| IPR024034 all species → | Homologous_superfamily | ATPase, F1/V1 complex, beta/alpha subunit, C-terminal | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR036121 all species → | Homologous_superfamily | ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily | Interproscan |
| IPR023366 all species → | Homologous_superfamily | ATP synthase subunit alpha, N-terminal domain-like superfamily | Interproscan |
| IPR031686 all species → | Domain | ATPsynthase alpha/beta subunit, N-terminal extension | Interproscan |
| IPR005725 all species → | Family | ATPase, V1 complex, subunit A | Interproscan |
| IPR004100 all species → | Domain | ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43607 all species → | V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0046034 all species → | Biological Process | ATP metabolic process | Interproscan |
| GO:0046961 all species → | Molecular Function | proton-transporting ATPase activity, rotational mechanism | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:1902600 all species → | Biological Process | proton transmembrane transport | Interproscan |
| GO:0005765 all species → | Cellular Component | lysosomal membrane | Interproscan |
| GO:0016887 all species → | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0033180 all species → | Cellular Component | proton-transporting V-type ATPase, V1 domain | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K02145 | ATPeV1A, ATP6A; V-type H+-transporting ATPase subunit A | EC:7.1.2.2 | Rheumatoid arthritis | ko05323 | deepkoala |
Transcript abundance of evm.model.Ap8.1926 across 49 RNA-seq samples of Astrangia poculata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · cold control | 14 | 0 | 0.00 | 0.00 | |
| whole organism · heat control | 12 | 0 | 0.00 | 0.00 | |
| whole organism · cold challenge | 12 | 0 | 0.00 | 0.00 | |
| whole organism · heat challenge | 11 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR10674714 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674715 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674724 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674733 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674734 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674735 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674736 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674737 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674739 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674743 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674746 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674747 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674748 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674750 | whole organism · cold control | whole organism | not recorded | cold control | SRP237293 | 0.00 |
| SRR10674706 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674707 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674708 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674717 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674718 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674720 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674721 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674725 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674731 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674741 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674752 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674753 | whole organism · heat control | whole organism | not recorded | heat control | SRP237293 | 0.00 |
| SRR10674711 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674712 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674713 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674722 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674723 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674730 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674732 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674738 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674740 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674744 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674745 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674749 | whole organism · cold challenge | whole organism | not recorded | cold challenge | SRP237293 | 0.00 |
| SRR10674709 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674710 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674716 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674719 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674726 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674727 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674728 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674729 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674742 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674751 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
| SRR10674754 | whole organism · heat challenge | whole organism | not recorded | heat challenge | SRP237293 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (APOCU_TPM,
StringTie quantification over 49 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Astrangia poculata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Astrangia poculata network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Astrangia poculata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
