Gene detail

Detailed information of evm.model.Ap8.2677 in Astrangia poculata

Genomic Location: Ap8:29234752...29275016
NR annotation: XP_020614730.1, DNA polymerase alpha catalytic subunit-like [Orbicella faveolata]
Species abbreviation APOCU · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

evm.model.Ap8.2677

atggcgccaacatctacagaggatgatccgacagcgacttctcaagatgattctcaatcaaccaggcgatcaaagagatctgcaaaacgtaatgccggagcaacttcggcactcgacaaaataaggaaattccgtcagactggggaaagatcgaagtttgaggttggcgaagtggcagatgtttaccaggtggtaaatgaagatgaatactctgacattgttaggaaacgccaggaagaagactgggtgattgatgatgatgggactggatatgttgatgatggaagagaaatttttgatgatgatcatgaggatgaaccatcaactggaaagaatgttcccaaattcaagccaaagaagccaaatgttaagaagccaacagtcaagccaaaatcaataaacaaaatgttgctagctgcaagtgccaaagcaaagaaaccaaagaatgaagttacgtctattggtgaagatgacttgttaaatgatcttctgaaggaagttgaggaatcgtctggcccaagacagaacattttcaaagttgaacccagatctccacctaaatccagttactccacaagtctgtctgcaaagagaaagactgttgtcaaaactgagccatcagaaacaagggaggggaggtacagtggcatggtaggcgatcatgatgggttaggacaagaggaagactatggagcagggatggatatggattcaggaatggatgatgatcctgttgcagttgacatggcagaacaggatacaggatgtgatgattttggcgatgacgatgatcttggtgatgcagaagcaattcaggcattaacaaatgccgagaatagtcaagatgagaaacctcatgtccaagttaaggtcgaggcaaaggagaagcagactgacagaaaatgtgctttttcaagaaaaacaaccgaaattcctggtgactctgcctgggaaacaatcttaggaaatgaagaatctcaacaacaagaggttctgacagatgtgaatgtggattcctcttccctcccacttcaggaagttgatggagaaaaagtcctcaagttttactggtttgatgcttatgaagatagattcaaacaaccaggtactgtttacctgtttggaaaagtgtggattgaatctgccaaagcatttgtcagttgttctgtggcagtcaagaacatagagagacaaatatttattcttccaagggaaaagaaacgagatgttgatggttctgagactaatgaacctgttggatttattgacgtttatcaggaattcaatgaaaagattgcaacaaaacacaaaatcatgaagttcatctccaggaaagttcaaaaggcttatgcttttgagattcaagatgttcctgtcacgtcagagtacctggaggtcagatattcagctgattgccctcagttaccatctgacctgtctggagaaacttttagccaagtgtttggaaccaacacctccagtcttgagcttcttctcctgagtcggaaaatgaaaggtccttgttggctcaacatcaagttgcctcaacttccccaacaacaagtcagttggtgtaaagtagaggctatagtctcaaagcctgatctccttgaagtagcaagtgaacaagaccctccaccacccatggttgttatgagcctcagttttaggacgatgttgaacaccaaaactcacacccatgagatcttggctgtgtcagctttggttcatcatgaggtgtcattagacaaagctgcaccaaaacagaagtttcaatatcatttctgtgttagtgaatttctttattcttatcatctgtccagtggcagaaccagaccttcagctgtaagcaaaccaaatgatcaaatgtacccttatgacttcaaagatgctgtcaggaaaaagcaaattaaaatggagattactacatcagagagagctcttctgggattgtttatggccaagattcacagaattgacccagatgtccttgtgggacatgacatctatggatttgatcttgatcttctgttgcacaggataaatgcttgtaagattcctcactggtctcgtcttggacggcttaaaagaactatcatgcctaagttgtctagtgggggacctggtaaaggcggcagtcttctcgatcgttccatcacttgtggacgaatggtgtgtgatgttaaaatctcttccaaagaacttataagatgcaagagctacgatttgacagcgttatcatgggctgttcttcagtctagaagagaagagattgaccaagatgaaatacccaacaagtttaaatggacgctttactgccttgggatcatgtatgatctaaacgttttgccgctggctttgcagataacaactattgctggaaatgttatggcccgaactctccttggtggccgatcggaaaggaatgaatttcttttgcttcacgccttcaacgaaaagaattttatctgccccgataaaagttatggcaaaaaacaagtggctgcagaggttgagaatgatgacgaagaccaacccaaaagttctaagaaggaagaagaaaaccagcttatgctggggactggtactggaaccgaaaaaggtttctacgacaaacacattctgttgctggatttcaacagtttgtacccgtccatcattcaggaatacaacatttgtttcacaacaatcagcagaacaagcttcccaactaccggaccgggtgacgaagaggaagtagttgaattacctgatcccgacttggagcctggcatattaccgactgagatcagaaaactggtggaacgaagaaaacaggtgaaagctttgatgaagaaccatggacgtgactcagatcaatatctgcagtatgatatcaggcagaaggccttgaagctcacagcaaacagtatgtacggctgtttgggattttctcattcacgtttttatgccaagccacttgctgctctggtaacaagcaaaggccgagagattttgctgaaaacgaaagaactagttcaaaacttgggacttgatgtgatttacggcgacacagattccatcatgattaacacgaataccacagacctcccagaagtccgcaaaatcggaaacaaggtgaaaaatgaggttaacaaactgtatcgattactggagatcgacattgatggcattttcaagtccatgcttttgctaaagaagaagaagtacgccgctatcagtatttctgaaaacgaggacggaacactgaatgaagtaaaggaaatgaaggggttggacattgtgaggagggactggtgcgacctcgcaaaggattcaggaaattacgtcctggctcaaatcttgtcttcgcaagcacgtgaaatgattgttgagaatatccatgactaccttatatcagttggagaaaacgttgccgaaggaaaagttgacattcagaagtttgttattaacaagcaattgaccaaatcgccccatgactaccccgacaagaagtctttggctcacgtgaacgtcgctctgcgcatgcttagtaaaggaaggaaagttaacgccggagacactataccctacgtcatctgtgacgatggttcaacactggctgccactcaacgagcctatcatccggatgagttctgcaagtcggacacgctgaagattgacgtgaaatattacctggctaatcaggttcatcctgttgtatctcgtttatgtgatcctattgacggcacggacgccgctcacattgcacagtgcctcggtttggatccgtctggttaccgtggtaactcggctatgcatgatgacgaaagtgacgcactgcttggcggccaggcccagatgaccgacgaggagagatttaaggactgcgaacgattcacagtaaaatgcaaacgtccaagttgtggtcaagaaacgtctattgaagtactgtttaaaaacacttcacatccatttggcctcaatgacacatgtcccggatgtaagaaccagtacagcgcgggcgctgtttcaaatcagctgactgttgccatgcgcaaacacattaaggagtattacataggatggcagaaatgcgatgatccgtcctgtggttacaccactcgtcaggtgcccctgacgcatcagcggggcgcccctatttgtacatcatgcttcagggctcacttacaccctgtgtactcggacactgcgctgtacactcaactgctttactactcacgcttgtttgactatgaatacgctctcaagaactccaaagaagacgccaagaaacttccacgcaaggctccgccattttacaccgctgttcactcgacagttaccaaagttctgaacaccaatggctattctgaagtgaatctttcaaaattgttcagtgctttcttcgtttaa

Transcript

evm.model.Ap8.2677

ATGGCGCCAACATCTACAGAGGATGATCCGACAGCGACTTCTCAAGATGATTCTCAATCAACCAGGCGATCAAAGAGATCTGCAAAACGTAATGCCGGAGCAACTTCGGCACTCGACAAAATAAGGAAATTCCGTCAGACTGGGGAAAGATCGAAGTTTGAGGTTGGCGAAGTGGCAGATGTTTACCAGGTGGTAAATGAAGATGAATACTCTGACATTGTTAGGAAACGCCAGGAAGAAGACTGGGTGATTGATGATGATGGGACTGGATATGTTGATGATGGAAGAGAAATTTTTGATGATGATCATGAGGATGAACCATCAACTGGAAAGAATGTTCCCAAATTCAAGCCAAAGAAGCCAAATGTTAAGAAGCCAACAGTCAAGCCAAAATCAATAAACAAAATGTTGCTAGCTGCAAGTGCCAAAGCAAAGAAACCAAAGAATGAAGTTACGTCTATTGGTGAAGATGACTTGTTAAATGATCTTCTGAAGGAAGTTGAGGAATCGTCTGGCCCAAGACAGAACATTTTCAAAGTTGAACCCAGATCTCCACCTAAATCCAGTTACTCCACAAGTCTGTCTGCAAAGAGAAAGACTGTTGTCAAAACTGAGCCATCAGAAACAAGGGAGGGGAGGTACAGTGGCATGGTAGGCGATCATGATGGGTTAGGACAAGAGGAAGACTATGGAGCAGGGATGGATATGGATTCAGGAATGGATGATGATCCTGTTGCAGTTGACATGGCAGAACAGGATACAGGATGTGATGATTTTGGCGATGACGATGATCTTGGTGATGCAGAAGCAATTCAGGCATTAACAAATGCCGAGAATAGTCAAGATGAGAAACCTCATGTCCAAGTTAAGGTCGAGGCAAAGGAGAAGCAGACTGACAGAAAATGTGCTTTTTCAAGAAAAACAACCGAAATTCCTGGTGACTCTGCCTGGGAAACAATCTTAGGAAATGAAGAATCTCAACAACAAGAGGTTCTGACAGATGTGAATGTGGATTCCTCTTCCCTCCCACTTCAGGAAGTTGATGGAGAAAAAGTCCTCAAGTTTTACTGGTTTGATGCTTATGAAGATAGATTCAAACAACCAGGTACTGTTTACCTGTTTGGAAAAGTGTGGATTGAATCTGCCAAAGCATTTGTCAGTTGTTCTGTGGCAGTCAAGAACATAGAGAGACAAATATTTATTCTTCCAAGGGAAAAGAAACGAGATGTTGATGGTTCTGAGACTAATGAACCTGTTGGATTTATTGACGTTTATCAGGAATTCAATGAAAAGATTGCAACAAAACACAAAATCATGAAGTTCATCTCCAGGAAAGTTCAAAAGGCTTATGCTTTTGAGATTCAAGATGTTCCTGTCACGTCAGAGTACCTGGAGGTCAGATATTCAGCTGATTGCCCTCAGTTACCATCTGACCTGTCTGGAGAAACTTTTAGCCAAGTGTTTGGAACCAACACCTCCAGTCTTGAGCTTCTTCTCCTGAGTCGGAAAATGAAAGGTCCTTGTTGGCTCAACATCAAGTTGCCTCAACTTCCCCAACAACAAGTCAGTTGGTGTAAAGTAGAGGCTATAGTCTCAAAGCCTGATCTCCTTGAAGTAGCAAGTGAACAAGACCCTCCACCACCCATGGTTGTTATGAGCCTCAGTTTTAGGACGATGTTGAACACCAAAACTCACACCCATGAGATCTTGGCTGTGTCAGCTTTGGTTCATCATGAGGTGTCATTAGACAAAGCTGCACCAAAACAGAAGTTTCAATATCATTTCTGTGTTAGTGAATTTCTTTATTCTTATCATCTGTCCAGTGGCAGAACCAGACCTTCAGCTGTAAGCAAACCAAATGATCAAATGTACCCTTATGACTTCAAAGATGCTGTCAGGAAAAAGCAAATTAAAATGGAGATTACTACATCAGAGAGAGCTCTTCTGGGATTGTTTATGGCCAAGATTCACAGAATTGACCCAGATGTCCTTGTGGGACATGACATCTATGGATTTGATCTTGATCTTCTGTTGCACAGGATAAATGCTTGTAAGATTCCTCACTGGTCTCGTCTTGGACGGCTTAAAAGAACTATCATGCCTAAGTTGTCTAGTGGGGGACCTGGTAAAGGCGGCAGTCTTCTCGATCGTTCCATCACTTGTGGACGAATGGTGTGTGATGTTAAAATCTCTTCCAAAGAACTTATAAGATGCAAGAGCTACGATTTGACAGCGTTATCATGGGCTGTTCTTCAGTCTAGAAGAGAAGAGATTGACCAAGATGAAATACCCAACAAGTTTAAATGGACGCTTTACTGCCTTGGGATCATGTATGATCTAAACGTTTTGCCGCTGGCTTTGCAGATAACAACTATTGCTGGAAATGTTATGGCCCGAACTCTCCTTGGTGGCCGATCGGAAAGGAATGAATTTCTTTTGCTTCACGCCTTCAACGAAAAGAATTTTATCTGCCCCGATAAAAGTTATGGCAAAAAACAAGTGGCTGCAGAGGTTGAGAATGATGACGAAGACCAACCCAAAAGTTCTAAGAAGGAAGAAGAAAACCAGCTTATGCTGGGGACTGGTACTGGAACCGAAAAAGGTTTCTACGACAAACACATTCTGTTGCTGGATTTCAACAGTTTGTACCCGTCCATCATTCAGGAATACAACATTTGTTTCACAACAATCAGCAGAACAAGCTTCCCAACTACCGGACCGGGTGACGAAGAGGAAGTAGTTGAATTACCTGATCCCGACTTGGAGCCTGGCATATTACCGACTGAGATCAGAAAACTGGTGGAACGAAGAAAACAGGTGAAAGCTTTGATGAAGAACCATGGACGTGACTCAGATCAATATCTGCAGTATGATATCAGGCAGAAGGCCTTGAAGCTCACAGCAAACAGTATGTACGGCTGTTTGGGATTTTCTCATTCACGTTTTTATGCCAAGCCACTTGCTGCTCTGGTAACAAGCAAAGGCCGAGAGATTTTGCTGAAAACGAAAGAACTAGTTCAAAACTTGGGACTTGATGTGATTTACGGCGACACAGATTCCATCATGATTAACACGAATACCACAGACCTCCCAGAAGTCCGCAAAATCGGAAACAAGGTGAAAAATGAGGTTAACAAACTGTATCGATTACTGGAGATCGACATTGATGGCATTTTCAAGTCCATGCTTTTGCTAAAGAAGAAGAAGTACGCCGCTATCAGTATTTCTGAAAACGAGGACGGAACACTGAATGAAGTAAAGGAAATGAAGGGGTTGGACATTGTGAGGAGGGACTGGTGCGACCTCGCAAAGGATTCAGGAAATTACGTCCTGGCTCAAATCTTGTCTTCGCAAGCACGTGAAATGATTGTTGAGAATATCCATGACTACCTTATATCAGTTGGAGAAAACGTTGCCGAAGGAAAAGTTGACATTCAGAAGTTTGTTATTAACAAGCAATTGACCAAATCGCCCCATGACTACCCCGACAAGAAGTCTTTGGCTCACGTGAACGTCGCTCTGCGCATGCTTAGTAAAGGAAGGAAAGTTAACGCCGGAGACACTATACCCTACGTCATCTGTGACGATGGTTCAACACTGGCTGCCACTCAACGAGCCTATCATCCGGATGAGTTCTGCAAGTCGGACACGCTGAAGATTGACGTGAAATATTACCTGGCTAATCAGGTTCATCCTGTTGTATCTCGTTTATGTGATCCTATTGACGGCACGGACGCCGCTCACATTGCACAGTGCCTCGGTTTGGATCCGTCTGGTTACCGTGGTAACTCGGCTATGCATGATGACGAAAGTGACGCACTGCTTGGCGGCCAGGCCCAGATGACCGACGAGGAGAGATTTAAGGACTGCGAACGATTCACAGTAAAATGCAAACGTCCAAGTTGTGGTCAAGAAACGTCTATTGAAGTACTGTTTAAAAACACTTCACATCCATTTGGCCTCAATGACACATGTCCCGGATGTAAGAACCAGTACAGCGCGGGCGCTGTTTCAAATCAGCTGACTGTTGCCATGCGCAAACACATTAAGGAGTATTACATAGGATGGCAGAAATGCGATGATCCGTCCTGTGGTTACACCACTCGTCAGGTGCCCCTGACGCATCAGCGGGGCGCCCCTATTTGTACATCATGCTTCAGGGCTCACTTACACCCTGTGTACTCGGACACTGCGCTGTACACTCAACTGCTTTACTACTCACGCTTGTTTGACTATGAATACGCTCTCAAGAACTCCAAAGAAGACGCCAAGAAACTTCCACGCAAGGCTCCGCCATTTTACACCGCTGTTCACTCGACAGTTACCAAAGTTCTGAACACCAATGGCTATTCTGAAGTGAATCTTTCAAAATTGTTCAGTGCTTTCTTCGTTTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9DE46	DNA polymerase alpha catalytic subunit OS=Xenopus laevis OX=8355 GN=pola1 PE=1 SV=1
P09884	DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2
P33609	DNA polymerase alpha catalytic subunit OS=Mus musculus OX=10090 GN=Pola1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001755 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00136 all species →	DNA_pol_B	DNA polymerase family B	Family	Interproscan
PF12254 all species →	DNA_pol_alpha_N	DNA polymerase alpha subunit p180 N terminal	Family	Interproscan
PF03104 all species →	DNA_pol_B_exo1	DNA polymerase family B, exonuclease domain	Family	Interproscan
PF08996 all species →	zf-DNA_Pol	DNA Polymerase alpha zinc finger	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR006134 all species →	Domain	DNA-directed DNA polymerase, family B, multifunctional domain	Interproscan
IPR006172 all species →	Family	DNA-directed DNA polymerase, family B	Interproscan
IPR036397 all species →	Homologous_superfamily	Ribonuclease H superfamily	Interproscan
IPR042087 all species →	Homologous_superfamily	DNA polymerase family B, thumb domain	Interproscan
IPR043502 all species →	Homologous_superfamily	DNA/RNA polymerase superfamily	Interproscan
IPR024647 all species →	Domain	DNA polymerase alpha catalytic subunit, N-terminal domain	Interproscan
IPR012337 all species →	Homologous_superfamily	Ribonuclease H-like superfamily	Interproscan
IPR023211 all species →	Homologous_superfamily	DNA polymerase, palm domain superfamily	Interproscan
IPR006133 all species →	Domain	DNA-directed DNA polymerase, family B, exonuclease domain	Interproscan
IPR038256 all species →	Homologous_superfamily	DNA polymerase alpha, zinc finger domain superfamily	Interproscan
IPR015088 all species →	Domain	Zinc finger, DNA-directed DNA polymerase, family B, alpha	Interproscan
IPR017964 all species →	Conserved_site	DNA-directed DNA polymerase, family B, conserved site	Interproscan
IPR045846 all species →	Domain	DNA polymerase alpha catalytic subunit, catalytic domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45861 all species →	DNA POLYMERASE ALPHA CATALYTIC SUBUNIT	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000166 all species →	Molecular Function	nucleotide binding	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0003887 all species →	Molecular Function	DNA-directed DNA polymerase activity	Interproscan
GO:0006260 all species →	Biological Process	DNA replication	Interproscan
GO:1902975 all species →	Biological Process	mitotic DNA replication initiation	Interproscan
GO:0003682 all species →	Molecular Function	chromatin binding	Interproscan
GO:0003688 all species →	Molecular Function	DNA replication origin binding	Interproscan
GO:0003697 all species →	Molecular Function	single-stranded DNA binding	Interproscan
GO:0005658 all species →	Cellular Component	alpha DNA polymerase:primase complex	Interproscan
GO:0006272 all species →	Biological Process	leading strand elongation	Interproscan
GO:0006273 all species →	Biological Process	lagging strand elongation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K02320	POLA1; DNA polymerase alpha subunit A	EC:2.7.7.7	DNA replication proteins	ko03032	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.