Detailed information of evm.model.Ap8.276 in Astrangia poculata

Genomic Location: Ap8:2762510...2770686
NR annotation: XP_020602753.1, beta-secretase 1-like [Orbicella faveolata]
Species abbreviation APOCU · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q2HJ40Beta-secretase 1 OS=Bos taurus OX=9913 GN=BACE1 PE=2 SV=1
P56817Beta-secretase 1 OS=Homo sapiens OX=9606 GN=BACE1 PE=1 SV=3
P56818Beta-secretase 1 OS=Mus musculus OX=10090 GN=Bace1 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0006562 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00026
all species →		AspEukaryotic aspartyl proteaseFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR021109
all species →		Homologous_superfamilyAspartic peptidase domain superfamilyInterproscan
IPR009120
all species →		FamilyBeta-secretase BACE1Interproscan
IPR033121
all species →		DomainPeptidase family A1 domainInterproscan
IPR009119
all species →		FamilyBeta-secretase BACEInterproscan
IPR001461
all species →		FamilyAspartic peptidase A1 familyInterproscan
IPR001969
all species →		Active_siteAspartic peptidase, active siteInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR47965
all species →		ASPARTYL PROTEASE-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004190
all species →		Molecular Functionaspartic-type endopeptidase activityInterproscan
GO:0006508
all species →		Biological ProcessproteolysisInterproscan
GO:0016020
all species →		Cellular ComponentmembraneInterproscan
GO:0005768
all species →		Cellular ComponentendosomeInterproscan
GO:0005802
all species →		Cellular Componenttrans-Golgi networkInterproscan
GO:0005886
all species →		Cellular Componentplasma membraneInterproscan
GO:0006509
all species →		Biological Processmembrane protein ectodomain proteolysisInterproscan
GO:0050435
all species →		Biological Processamyloid-beta metabolic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K04521BACE1; beta-site APP-cleaving enzyme 1 (memapsin 2)EC:3.4.23.46
Peptidases and inhibitorsko01002deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.
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