Genomic Location: Ap9:17426593...17436964
NR annotation: KAJ7365650.1, Isoleucine--tRNA ligase, cytoplasmic [Desmophyllum pertusum]
Species Astrangia poculata · all data for this species · gene families
| CDS |
| evm.model.Ap9.1606 |
| Transcript |
| evm.model.Ap9.1606 |
| Protein |
| evm.model.Ap9.1606 |
| UniProt accession | Description |
|---|---|
| Q6P4Y6 | Insulin receptor substrate 1 OS=Xenopus tropicalis OX=8364 GN=irs1 PE=2 SV=1 |
| P84770 | Insulin receptor substrate 1-B OS=Xenopus laevis OX=8355 GN=irs1-b PE=2 SV=1 |
| P35570 | Insulin receptor substrate 1 OS=Rattus norvegicus OX=10116 GN=Irs1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0007882 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02174 all species → | IRS | PTB domain (IRS-1 type) | Domain | Interproscan |
| PF00169 all species → | PH | PH domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002404 all species → | Domain | IRS-type PTB domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR039011 all species → | Family | Insulin receptor substrate | Interproscan |
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10614 all species → | INSULIN RECEPTOR SUBSTRATE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005158 all species → | Molecular Function | insulin receptor binding | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0008286 all species → | Biological Process | insulin receptor signaling pathway | Interproscan |
| GO:0043548 all species → | Molecular Function | phosphatidylinositol 3-kinase binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K16172 | IRS1; insulin receptor substrate 1 | - | Insulin resistance | ko04931 | deepkoala |
Transcript abundance of evm.model.Ap9.1606 across 49 RNA-seq samples of Astrangia poculata. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · cold control | 14 | 0 | 0.00 | 0.00 | |
| whole organism · heat control | 12 | 0 | 0.00 | 0.00 | |
| whole organism · cold challenge | 12 | 0 | 0.00 | 0.00 | |
| whole organism · heat challenge | 11 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (APOCU_TPM,
StringTie quantification over 49 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
