Detailed information of evm.model.ptg000006l.109 in Aurelia coerulea

Genomic Location: chr3:1802589...1832815
NR annotation: XP_001627081.1, T-complex protein 1 subunit beta [Nematostella vectensis]
Species Aurelia coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q3ZBH0T-complex protein 1 subunit beta OS=Bos taurus OX=9913 GN=CCT2 PE=1 SV=3
P78371T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4
Q4R6F8T-complex protein 1 subunit beta OS=Macaca fascicularis OX=9541 GN=CCT2 PE=2 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005460 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00118
all species →
Cpn60_TCP1TCP-1/cpn60 chaperonin familyFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR027413
all species →
Homologous_superfamilyGroEL-like equatorial domain superfamilyInterproscan
IPR002194
all species →
Conserved_siteChaperonin TCP-1, conserved siteInterproscan
IPR012716
all species →
FamilyT-complex protein 1, beta subunitInterproscan
IPR017998
all species →
FamilyChaperone tailless complex polypeptide 1 (TCP-1)Interproscan
IPR027410
all species →
Homologous_superfamilyTCP-1-like chaperonin intermediate domain superfamilyInterproscan
IPR053374
all species →
FamilyTCP-1 chaperonin-containing T-complexInterproscan
IPR002423
all species →
FamilyChaperonin Cpn60/GroEL/TCP-1 familyInterproscan
IPR027409
all species →
Homologous_superfamilyGroEL-like apical domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11353
all species →
CHAPERONINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0006457
all species →
Biological Processprotein foldingInterproscan
GO:0016887
all species →
Molecular FunctionATP hydrolysis activityInterproscan
GO:0051082
all species →
Molecular Functionunfolded protein bindingInterproscan
GO:0005829
all species →
Cellular ComponentcytosolInterproscan
GO:0005832
all species →
Cellular Componentchaperonin-containing T-complexInterproscan
GO:0140662
all species →
Molecular FunctionATP-dependent protein folding chaperoneInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K09494CCT2; T-complex protein 1 subunit beta-Exosomeko04147deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of evm.model.ptg000006l.109 across 30 RNA-seq samples of Aurelia coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

30Samples
30TPM > 0
30Conditions
362.8Max TPM
247.9Mean TPM

By condition

Every sample in this dataset carries its own condition — the source metadata gives each run a distinct treatment label — so this table is effectively a sample list. The per-sample chart below is the informative view here.

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organism · T_A1ES 1 1 215.06 215.06
whole organism · T_C3E 1 1 255.80 255.80
whole organism · T_C2P 1 1 216.77 216.77
whole organism · T_A2ES 1 1 188.13 188.13
whole organism · T_A3ES 1 1 210.67 210.67
whole organism · T_C1AS 1 1 233.84 233.84
whole organism · T_C2AS 1 1 244.78 244.78
whole organism · T_C3AS 1 1 226.02 226.02
whole organism · T_A1AS 1 1 288.89 288.89
whole organism · T_A2AS 1 1 288.07 288.07
whole organism · T_A3AS 1 1 291.41 291.41
whole organism · T_C1E 1 1 225.67 225.67
whole organism · T_C2E 1 1 246.62 246.62
whole organism · T_C3P 1 1 193.88 193.88
whole organism · T_AE1 1 1 284.67 284.67
whole organism · T_C3ES 1 1 217.65 217.65
whole organism · T_AE2 1 1 299.23 299.23
whole organism · T_AE3 1 1 297.70 297.70
whole organism · T_AES1 1 1 362.76 362.76
whole organism · T_AES2 1 1 348.74 348.74
whole organism · T_AES3 1 1 304.82 304.82
whole organism · T_AAS1 1 1 313.36 313.36
whole organism · T_AAS2 1 1 228.55 228.55
whole organism · T_AAS3 1 1 277.77 277.77
whole organism · T_A1P 1 1 155.99 155.99
whole organism · T_A2P 1 1 170.26 170.26
whole organism · T_A3P 1 1 190.98 190.98
whole organism · T_C1ES 1 1 224.88 224.88
whole organism · T_C2ES 1 1 244.95 244.95
whole organism · T_C1P 1 1 189.04 189.04

Per sample · hover a bar for the full sample record

Show the sample table (30 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR25982246 whole organism · T_A1ES whole organism not recorded T_A1ES SRP459341 215.06
SRR25982262 whole organism · T_C3E whole organism not recorded T_C3E SRP459341 255.80
SRR25982274 whole organism · T_C2P whole organism not recorded T_C2P SRP459341 216.77
SRR25982273 whole organism · T_A2ES whole organism not recorded T_A2ES SRP459341 188.13
SRR25982272 whole organism · T_A3ES whole organism not recorded T_A3ES SRP459341 210.67
SRR25982271 whole organism · T_C1AS whole organism not recorded T_C1AS SRP459341 233.84
SRR25982270 whole organism · T_C2AS whole organism not recorded T_C2AS SRP459341 244.78
SRR25982269 whole organism · T_C3AS whole organism not recorded T_C3AS SRP459341 226.02
SRR25982268 whole organism · T_A1AS whole organism not recorded T_A1AS SRP459341 288.89
SRR25982267 whole organism · T_A2AS whole organism not recorded T_A2AS SRP459341 288.07
SRR25982266 whole organism · T_A3AS whole organism not recorded T_A3AS SRP459341 291.41
SRR25982265 whole organism · T_C1E whole organism not recorded T_C1E SRP459341 225.67
SRR25982264 whole organism · T_C2E whole organism not recorded T_C2E SRP459341 246.62
SRR25982263 whole organism · T_C3P whole organism not recorded T_C3P SRP459341 193.88
SRR25982261 whole organism · T_AE1 whole organism not recorded T_AE1 SRP459341 284.67
SRR25982247 whole organism · T_C3ES whole organism not recorded T_C3ES SRP459341 217.65
SRR25982260 whole organism · T_AE2 whole organism not recorded T_AE2 SRP459341 299.23
SRR25982259 whole organism · T_AE3 whole organism not recorded T_AE3 SRP459341 297.70
SRR25982258 whole organism · T_AES1 whole organism not recorded T_AES1 SRP459341 362.76
SRR25982257 whole organism · T_AES2 whole organism not recorded T_AES2 SRP459341 348.74
SRR25982256 whole organism · T_AES3 whole organism not recorded T_AES3 SRP459341 304.82
SRR25982255 whole organism · T_AAS1 whole organism not recorded T_AAS1 SRP459341 313.36
SRR25982254 whole organism · T_AAS2 whole organism not recorded T_AAS2 SRP459341 228.55
SRR25982253 whole organism · T_AAS3 whole organism not recorded T_AAS3 SRP459341 277.77
SRR25982252 whole organism · T_A1P whole organism not recorded T_A1P SRP459341 155.99
SRR25982251 whole organism · T_A2P whole organism not recorded T_A2P SRP459341 170.26
SRR25982250 whole organism · T_A3P whole organism not recorded T_A3P SRP459341 190.98
SRR25982249 whole organism · T_C1ES whole organism not recorded T_C1ES SRP459341 224.88
SRR25982248 whole organism · T_C2ES whole organism not recorded T_C2ES SRP459341 244.95
SRR25982275 whole organism · T_C1P whole organism not recorded T_C1P SRP459341 189.04

Source: CnidoSite RNA-seq expression matrices (ACOER_TPM, StringTie quantification over 30 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Aurelia coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated25evm.model.ptg000037l.980.956886595694177
Negatively correlated4evm.model.ptg000012l.793-0.859759365327996

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Aurelia coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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