Genomic Location: chr3:7572783...7696874
NR annotation: XP_027040972.1, dynein heavy chain 1, axonemal-like [Pocillopora damicornis]
Species Aurelia coerulea · all data for this species · gene families
| CDS |
| evm.model.ptg000006l.380 |
| Transcript |
| evm.model.ptg000006l.380 |
| Protein |
| evm.model.ptg000006l.380 |
| UniProt accession | Description |
|---|---|
| E9Q8T7 | Dynein axonemal heavy chain 1 OS=Mus musculus OX=10090 GN=Dnah1 PE=1 SV=1 |
| Q9P2D7 | Dynein axonemal heavy chain 1 OS=Homo sapiens OX=9606 GN=DNAH1 PE=1 SV=6 |
| Q63164 | Dynein axonemal heavy chain 1 OS=Rattus norvegicus OX=10116 GN=Dnah1 PE=2 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000139 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08393 all species → | DHC_N2 | Dynein heavy chain, N-terminal region 2 | Family | Interproscan |
| PF12781 all species → | AAA_9 | ATP-binding dynein motor region | Domain | Interproscan |
| PF12780 all species → | AAA_8 | P-loop containing dynein motor region D4 | Domain | Interproscan |
| PF12775 all species → | AAA_7 | P-loop containing dynein motor region | Domain | Interproscan |
| PF18198 all species → | AAA_lid_11 | Dynein heavy chain AAA lid domain | Domain | Interproscan |
| PF03028 all species → | Dynein_heavy | Dynein heavy chain region D6 P-loop domain | Domain | Interproscan |
| PF12777 all species → | MT | Microtubule-binding stalk of dynein motor | Domain | Interproscan |
| PF12774 all species → | AAA_6 | Hydrolytic ATP binding site of dynein motor region | Domain | Interproscan |
| PF18199 all species → | Dynein_C | Dynein heavy chain C-terminal domain | Domain | Interproscan |
| PF17857 all species → | AAA_lid_1 | AAA+ lid domain | Domain | Interproscan |
| PF17852 all species → | Dynein_AAA_lid | Dynein heavy chain AAA lid domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR013602 all species → | Domain | Dynein heavy chain, linker | Interproscan |
| IPR042219 all species → | Homologous_superfamily | Dynein heavy chain AAA lid domain superfamily | Interproscan |
| IPR035706 all species → | Domain | Dynein heavy chain, ATP-binding dynein motor region | Interproscan |
| IPR043157 all species → | Homologous_superfamily | Dynein heavy chain, AAA1 domain, small subdomain | Interproscan |
| IPR024317 all species → | Domain | Dynein heavy chain, AAA module D4 | Interproscan |
| IPR026983 all species → | Family | Dynein heavy chain | Interproscan |
| IPR043160 all species → | Homologous_superfamily | Dynein heavy chain, C-terminal domain, barrel region | Interproscan |
| IPR041658 all species → | Domain | Dynein heavy chain AAA lid domain | Interproscan |
| IPR042222 all species → | Homologous_superfamily | Dynein heavy chain, domain 2, N-terminal | Interproscan |
| IPR004273 all species → | Domain | Dynein heavy chain region D6 P-loop domain | Interproscan |
| IPR024743 all species → | Domain | Dynein heavy chain, coiled coil stalk | Interproscan |
| IPR035699 all species → | Domain | Dynein heavy chain, hydrolytic ATP-binding dynein motor region | Interproscan |
| IPR042228 all species → | Homologous_superfamily | Dynein heavy chain, linker, subdomain 3 | Interproscan |
| IPR041228 all species → | Domain | Dynein heavy chain, C-terminal domain | Interproscan |
| IPR041589 all species → | Domain | Dynein heavy chain 3, AAA+ lid domain | Interproscan |
| IPR041466 all species → | Domain | Dynein heavy chain, AAA 5 extension domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46961 all species → | DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0007018 all species → | Biological Process | microtubule-based movement | Interproscan |
| GO:0030286 all species → | Cellular Component | dynein complex | Interproscan |
| GO:0045505 all species → | Molecular Function | dynein intermediate chain binding | Interproscan |
| GO:0051959 all species → | Molecular Function | dynein light intermediate chain binding | Interproscan |
| GO:0008569 all species → | Molecular Function | minus-end-directed microtubule motor activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10408 | DNAH; dynein axonemal heavy chain | - | Cytoskeleton proteins | ko04812 | deepkoala |
Transcript abundance of evm.model.ptg000006l.380 across 30 RNA-seq samples of Aurelia coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
Every sample in this dataset carries its own condition — the source metadata gives each run a distinct treatment label — so this table is effectively a sample list. The per-sample chart below is the informative view here.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · T_A1ES | 1 | 1 | 0.19 | 0.19 | |
| whole organism · T_C3E | 1 | 1 | 1.67 | 1.67 | |
| whole organism · T_C2P | 1 | 1 | 0.25 | 0.25 | |
| whole organism · T_A2ES | 1 | 1 | 0.47 | 0.47 | |
| whole organism · T_A3ES | 1 | 1 | 0.55 | 0.55 | |
| whole organism · T_C1AS | 1 | 1 | 0.23 | 0.23 | |
| whole organism · T_C2AS | 1 | 1 | 0.37 | 0.37 | |
| whole organism · T_C3AS | 1 | 1 | 0.29 | 0.29 | |
| whole organism · T_A1AS | 1 | 1 | 0.70 | 0.70 | |
| whole organism · T_A2AS | 1 | 1 | 0.66 | 0.66 | |
| whole organism · T_A3AS | 1 | 1 | 0.71 | 0.71 | |
| whole organism · T_C1E | 1 | 1 | 1.16 | 1.16 | |
| whole organism · T_C2E | 1 | 1 | 1.01 | 1.01 | |
| whole organism · T_C3P | 1 | 1 | 0.23 | 0.23 | |
| whole organism · T_AE1 | 1 | 1 | 1.82 | 1.82 | |
| whole organism · T_C3ES | 1 | 1 | 0.22 | 0.22 | |
| whole organism · T_AE2 | 1 | 1 | 2.50 | 2.50 | |
| whole organism · T_AE3 | 1 | 1 | 2.12 | 2.12 | |
| whole organism · T_AES1 | 1 | 1 | 0.90 | 0.90 | |
| whole organism · T_AES2 | 1 | 1 | 0.87 | 0.87 | |
| whole organism · T_AES3 | 1 | 1 | 1.48 | 1.48 | |
| whole organism · T_AAS1 | 1 | 1 | 1.22 | 1.22 | |
| whole organism · T_AAS2 | 1 | 1 | 1.08 | 1.08 | |
| whole organism · T_AAS3 | 1 | 1 | 1.14 | 1.14 | |
| whole organism · T_A1P | 1 | 1 | 0.29 | 0.29 | |
| whole organism · T_A2P | 1 | 1 | 0.09 | 0.09 | |
| whole organism · T_A3P | 1 | 0 | 0.00 | 0.00 | |
| whole organism · T_C1ES | 1 | 1 | 0.23 | 0.23 | |
| whole organism · T_C2ES | 1 | 1 | 0.24 | 0.24 | |
| whole organism · T_C1P | 1 | 1 | 0.26 | 0.26 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR25982246 | whole organism · T_A1ES | whole organism | not recorded | T_A1ES | SRP459341 | 0.19 |
| SRR25982262 | whole organism · T_C3E | whole organism | not recorded | T_C3E | SRP459341 | 1.67 |
| SRR25982274 | whole organism · T_C2P | whole organism | not recorded | T_C2P | SRP459341 | 0.25 |
| SRR25982273 | whole organism · T_A2ES | whole organism | not recorded | T_A2ES | SRP459341 | 0.47 |
| SRR25982272 | whole organism · T_A3ES | whole organism | not recorded | T_A3ES | SRP459341 | 0.55 |
| SRR25982271 | whole organism · T_C1AS | whole organism | not recorded | T_C1AS | SRP459341 | 0.23 |
| SRR25982270 | whole organism · T_C2AS | whole organism | not recorded | T_C2AS | SRP459341 | 0.37 |
| SRR25982269 | whole organism · T_C3AS | whole organism | not recorded | T_C3AS | SRP459341 | 0.29 |
| SRR25982268 | whole organism · T_A1AS | whole organism | not recorded | T_A1AS | SRP459341 | 0.70 |
| SRR25982267 | whole organism · T_A2AS | whole organism | not recorded | T_A2AS | SRP459341 | 0.66 |
| SRR25982266 | whole organism · T_A3AS | whole organism | not recorded | T_A3AS | SRP459341 | 0.71 |
| SRR25982265 | whole organism · T_C1E | whole organism | not recorded | T_C1E | SRP459341 | 1.16 |
| SRR25982264 | whole organism · T_C2E | whole organism | not recorded | T_C2E | SRP459341 | 1.01 |
| SRR25982263 | whole organism · T_C3P | whole organism | not recorded | T_C3P | SRP459341 | 0.23 |
| SRR25982261 | whole organism · T_AE1 | whole organism | not recorded | T_AE1 | SRP459341 | 1.82 |
| SRR25982247 | whole organism · T_C3ES | whole organism | not recorded | T_C3ES | SRP459341 | 0.22 |
| SRR25982260 | whole organism · T_AE2 | whole organism | not recorded | T_AE2 | SRP459341 | 2.50 |
| SRR25982259 | whole organism · T_AE3 | whole organism | not recorded | T_AE3 | SRP459341 | 2.12 |
| SRR25982258 | whole organism · T_AES1 | whole organism | not recorded | T_AES1 | SRP459341 | 0.90 |
| SRR25982257 | whole organism · T_AES2 | whole organism | not recorded | T_AES2 | SRP459341 | 0.87 |
| SRR25982256 | whole organism · T_AES3 | whole organism | not recorded | T_AES3 | SRP459341 | 1.48 |
| SRR25982255 | whole organism · T_AAS1 | whole organism | not recorded | T_AAS1 | SRP459341 | 1.22 |
| SRR25982254 | whole organism · T_AAS2 | whole organism | not recorded | T_AAS2 | SRP459341 | 1.08 |
| SRR25982253 | whole organism · T_AAS3 | whole organism | not recorded | T_AAS3 | SRP459341 | 1.14 |
| SRR25982252 | whole organism · T_A1P | whole organism | not recorded | T_A1P | SRP459341 | 0.29 |
| SRR25982251 | whole organism · T_A2P | whole organism | not recorded | T_A2P | SRP459341 | 0.09 |
| SRR25982250 | whole organism · T_A3P | whole organism | not recorded | T_A3P | SRP459341 | 0.00 |
| SRR25982249 | whole organism · T_C1ES | whole organism | not recorded | T_C1ES | SRP459341 | 0.23 |
| SRR25982248 | whole organism · T_C2ES | whole organism | not recorded | T_C2ES | SRP459341 | 0.24 |
| SRR25982275 | whole organism · T_C1P | whole organism | not recorded | T_C1P | SRP459341 | 0.26 |
Source: CnidoSite RNA-seq expression matrices (ACOER_TPM,
StringTie quantification over 30 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Aurelia coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 16 | evm.model.ptg000003l.148 | 0.96331350861236 |
| Negatively correlated | 4 | evm.model.ptg000020l.49 | -0.840384331329088 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Aurelia coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
