Detailed information of evm.model.ptg000006l.387 in Aurelia coerulea

Genomic Location: chr3:7821962...7908143
NR annotation: CAH3159890.1, unnamed protein product [Porites evermanni]
Species Aurelia coerulea · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P11029Acetyl-CoA carboxylase OS=Gallus gallus OX=9031 GN=ACAC PE=1 SV=1
Q5SWU9Acetyl-CoA carboxylase 1 OS=Mus musculus OX=10090 GN=Acaca PE=1 SV=1
P11497Acetyl-CoA carboxylase 1 OS=Rattus norvegicus OX=10116 GN=Acaca PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002191 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF21385
all species →
ACCA_BTAcetyl-CoA carboxylase, BT domainDomainInterproscan
PF02785
all species →
Biotin_carb_CBiotin carboxylase C-terminal domainDomainInterproscan
PF00364
all species →
Biotin_lipoylBiotin-requiring enzymeDomainInterproscan
PF01039
all species →
Carboxyl_transCarboxyl transferase domainFamilyInterproscan
PF00289
all species →
Biotin_carb_NBiotin carboxylase, N-terminal domainDomainInterproscan
PF02786
all species →
CPSase_L_D2Carbamoyl-phosphate synthase L chain, ATP binding domainDomainInterproscan
PF08326
all species →
ACC_centralAcetyl-CoA carboxylase, central regionFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR049074
all species →
DomainAcetyl-CoA carboxylase, BT domainInterproscan
IPR005479
all species →
DomainCarbamoyl-phosphate synthetase large subunit-like, ATP-binding domainInterproscan
IPR011763
all species →
DomainAcetyl-coenzyme A carboxyltransferase, C-terminalInterproscan
IPR005482
all species →
DomainBiotin carboxylase, C-terminalInterproscan
IPR000089
all species →
DomainBiotin/lipoyl attachmentInterproscan
IPR034733
all species →
DomainAcetyl-coenzyme A carboxylase carboxyl transferase subunit betaInterproscan
IPR016185
all species →
Homologous_superfamilyPre-ATP-grasp domain superfamilyInterproscan
IPR005481
all species →
DomainBiotin carboxylase-like, N-terminal domainInterproscan
IPR001882
all species →
Binding_siteBiotin-binding siteInterproscan
IPR011761
all species →
DomainATP-grasp foldInterproscan
IPR049076
all species →
FamilyAcetyl-CoA carboxylaseInterproscan
IPR029045
all species →
Homologous_superfamilyClpP/crotonase-like domain superfamilyInterproscan
IPR013537
all species →
DomainAcetyl-CoA carboxylase, central domainInterproscan
IPR011054
all species →
Homologous_superfamilyRudiment single hybrid motifInterproscan
IPR011762
all species →
DomainAcetyl-coenzyme A carboxyltransferase, N-terminalInterproscan
IPR011764
all species →
DomainBiotin carboxylation domainInterproscan
IPR011053
all species →
Homologous_superfamilySingle hybrid motifInterproscan
IPR013815
all species →
Homologous_superfamilyATP-grasp fold, subdomain 1Interproscan

 PANTHER
PANTHER termDescriptionSource
PTHR45728
all species →
ACETYL-COA CARBOXYLASE, ISOFORM AInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0016874
all species →
Molecular Functionligase activityInterproscan
GO:0046872
all species →
Molecular Functionmetal ion bindingInterproscan
GO:0003989
all species →
Molecular Functionacetyl-CoA carboxylase activityInterproscan
GO:0005739
all species →
Cellular ComponentmitochondrionInterproscan
GO:0006633
all species →
Biological Processfatty acid biosynthetic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K11262ACACA; acetyl-CoA carboxylase / biotin carboxylase 1EC:6.4.1.2
EC:6.3.4.14
EC:2.1.3.15
Alcoholic liver diseaseko04936deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of evm.model.ptg000006l.387 across 30 RNA-seq samples of Aurelia coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

30Samples
30TPM > 0
30Conditions
8.2Max TPM
3.5Mean TPM

By condition

Every sample in this dataset carries its own condition — the source metadata gives each run a distinct treatment label — so this table is effectively a sample list. The per-sample chart below is the informative view here.

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organism · T_A1ES 1 1 1.58 1.58
whole organism · T_C3E 1 1 4.65 4.65
whole organism · T_C2P 1 1 1.13 1.13
whole organism · T_A2ES 1 1 2.34 2.34
whole organism · T_A3ES 1 1 2.30 2.30
whole organism · T_C1AS 1 1 1.52 1.52
whole organism · T_C2AS 1 1 1.79 1.79
whole organism · T_C3AS 1 1 1.15 1.15
whole organism · T_A1AS 1 1 7.22 7.22
whole organism · T_A2AS 1 1 4.64 4.64
whole organism · T_A3AS 1 1 4.78 4.78
whole organism · T_C1E 1 1 4.11 4.11
whole organism · T_C2E 1 1 5.61 5.61
whole organism · T_C3P 1 1 1.12 1.12
whole organism · T_AE1 1 1 7.76 7.76
whole organism · T_C3ES 1 1 1.01 1.01
whole organism · T_AE2 1 1 7.94 7.94
whole organism · T_AE3 1 1 8.19 8.19
whole organism · T_AES1 1 1 6.92 6.92
whole organism · T_AES2 1 1 7.82 7.82
whole organism · T_AES3 1 1 4.33 4.33
whole organism · T_AAS1 1 1 4.70 4.70
whole organism · T_AAS2 1 1 3.50 3.50
whole organism · T_AAS3 1 1 3.46 3.46
whole organism · T_A1P 1 1 0.74 0.74
whole organism · T_A2P 1 1 0.53 0.53
whole organism · T_A3P 1 1 0.88 0.88
whole organism · T_C1ES 1 1 1.33 1.33
whole organism · T_C2ES 1 1 1.13 1.13
whole organism · T_C1P 1 1 0.66 0.66

Per sample · hover a bar for the full sample record

Show the sample table (30 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR25982246 whole organism · T_A1ES whole organism not recorded T_A1ES SRP459341 1.58
SRR25982262 whole organism · T_C3E whole organism not recorded T_C3E SRP459341 4.65
SRR25982274 whole organism · T_C2P whole organism not recorded T_C2P SRP459341 1.13
SRR25982273 whole organism · T_A2ES whole organism not recorded T_A2ES SRP459341 2.34
SRR25982272 whole organism · T_A3ES whole organism not recorded T_A3ES SRP459341 2.30
SRR25982271 whole organism · T_C1AS whole organism not recorded T_C1AS SRP459341 1.52
SRR25982270 whole organism · T_C2AS whole organism not recorded T_C2AS SRP459341 1.79
SRR25982269 whole organism · T_C3AS whole organism not recorded T_C3AS SRP459341 1.15
SRR25982268 whole organism · T_A1AS whole organism not recorded T_A1AS SRP459341 7.22
SRR25982267 whole organism · T_A2AS whole organism not recorded T_A2AS SRP459341 4.64
SRR25982266 whole organism · T_A3AS whole organism not recorded T_A3AS SRP459341 4.78
SRR25982265 whole organism · T_C1E whole organism not recorded T_C1E SRP459341 4.11
SRR25982264 whole organism · T_C2E whole organism not recorded T_C2E SRP459341 5.61
SRR25982263 whole organism · T_C3P whole organism not recorded T_C3P SRP459341 1.12
SRR25982261 whole organism · T_AE1 whole organism not recorded T_AE1 SRP459341 7.76
SRR25982247 whole organism · T_C3ES whole organism not recorded T_C3ES SRP459341 1.01
SRR25982260 whole organism · T_AE2 whole organism not recorded T_AE2 SRP459341 7.94
SRR25982259 whole organism · T_AE3 whole organism not recorded T_AE3 SRP459341 8.19
SRR25982258 whole organism · T_AES1 whole organism not recorded T_AES1 SRP459341 6.92
SRR25982257 whole organism · T_AES2 whole organism not recorded T_AES2 SRP459341 7.82
SRR25982256 whole organism · T_AES3 whole organism not recorded T_AES3 SRP459341 4.33
SRR25982255 whole organism · T_AAS1 whole organism not recorded T_AAS1 SRP459341 4.70
SRR25982254 whole organism · T_AAS2 whole organism not recorded T_AAS2 SRP459341 3.50
SRR25982253 whole organism · T_AAS3 whole organism not recorded T_AAS3 SRP459341 3.46
SRR25982252 whole organism · T_A1P whole organism not recorded T_A1P SRP459341 0.74
SRR25982251 whole organism · T_A2P whole organism not recorded T_A2P SRP459341 0.53
SRR25982250 whole organism · T_A3P whole organism not recorded T_A3P SRP459341 0.88
SRR25982249 whole organism · T_C1ES whole organism not recorded T_C1ES SRP459341 1.33
SRR25982248 whole organism · T_C2ES whole organism not recorded T_C2ES SRP459341 1.13
SRR25982275 whole organism · T_C1P whole organism not recorded T_C1P SRP459341 0.66

Source: CnidoSite RNA-seq expression matrices (ACOER_TPM, StringTie quantification over 30 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Aurelia coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated19evm.model.ptg000049l.520.970577573489433
Negatively correlated4evm.model.ptg000007l.783-0.885714723417953

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Aurelia coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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