Genomic Location: chr13:1798699...1814275
NR annotation: XP_002162239.2, eukaryotic translation initiation factor 2 subunit 3, Y-linked [Hydra vulgaris]
Species Aurelia coerulea · all data for this species · gene families
| CDS |
| evm.model.ptg000009l.1062 |
| Transcript |
| evm.model.ptg000009l.1062 |
| Protein |
| evm.model.ptg000009l.1062 |
| UniProt accession | Description |
|---|---|
| F1QGW6 | Eukaryotic translation initiation factor 2 subunit 3 OS=Danio rerio OX=7955 GN=eif2s3 PE=3 SV=1 |
| Q2KHU8 | Eukaryotic translation initiation factor 2 subunit 3 OS=Bos taurus OX=9913 GN=EIF2S3 PE=2 SV=1 |
| Q5ZMS3 | Eukaryotic translation initiation factor 2 subunit 3 OS=Gallus gallus OX=9031 GN=EIF2S3 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0007198 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF09173 all species → | eIF2_C | Initiation factor eIF2 gamma, C terminal | Domain | Interproscan |
| PF03144 all species → | GTP_EFTU_D2 | Elongation factor Tu domain 2 | Domain | Interproscan |
| PF00009 all species → | GTP_EFTU | Elongation factor Tu GTP binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR044127 all species → | Domain | Initiation factor eIF2 gamma, domain 2 | Interproscan |
| IPR050543 all species → | Family | Eukaryotic Initiation Factor 2 Gamma Subunit | Interproscan |
| IPR009001 all species → | Homologous_superfamily | Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal | Interproscan |
| IPR015256 all species → | Domain | Initiation factor eIF2 gamma, C-terminal | Interproscan |
| IPR000795 all species → | Domain | Translational (tr)-type GTP-binding domain | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR009000 all species → | Homologous_superfamily | Translation protein, beta-barrel domain superfamily | Interproscan |
| IPR004161 all species → | Domain | Translation elongation factor EFTu-like, domain 2 | Interproscan |
| IPR044128 all species → | Domain | Initiation factor eIF2 gamma, GTP-binding domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR42854 all species → | EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000049 all species → | Molecular Function | tRNA binding | Interproscan |
| GO:0001731 all species → | Biological Process | formation of translation preinitiation complex | Interproscan |
| GO:0003743 all species → | Molecular Function | translation initiation factor activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0005850 all species → | Cellular Component | eukaryotic translation initiation factor 2 complex | Interproscan |
| GO:0003924 all species → | Molecular Function | GTPase activity | Interproscan |
| GO:0005525 all species → | Molecular Function | GTP binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03242 | EIF2S3; translation initiation factor 2 subunit 3 | - | Translation factors | ko03012 | deepkoala |
Transcript abundance of evm.model.ptg000009l.1062 across 30 RNA-seq samples of Aurelia coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
Every sample in this dataset carries its own condition — the source metadata gives each run a distinct treatment label — so this table is effectively a sample list. The per-sample chart below is the informative view here.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · T_A1ES | 1 | 1 | 292.90 | 292.90 | |
| whole organism · T_C3E | 1 | 1 | 427.72 | 427.72 | |
| whole organism · T_C2P | 1 | 1 | 298.60 | 298.60 | |
| whole organism · T_A2ES | 1 | 1 | 261.24 | 261.24 | |
| whole organism · T_A3ES | 1 | 1 | 304.79 | 304.79 | |
| whole organism · T_C1AS | 1 | 1 | 261.39 | 261.39 | |
| whole organism · T_C2AS | 1 | 1 | 276.07 | 276.07 | |
| whole organism · T_C3AS | 1 | 1 | 282.77 | 282.77 | |
| whole organism · T_A1AS | 1 | 1 | 262.94 | 262.94 | |
| whole organism · T_A2AS | 1 | 1 | 261.55 | 261.55 | |
| whole organism · T_A3AS | 1 | 1 | 279.44 | 279.44 | |
| whole organism · T_C1E | 1 | 1 | 366.76 | 366.76 | |
| whole organism · T_C2E | 1 | 1 | 390.08 | 390.08 | |
| whole organism · T_C3P | 1 | 1 | 312.82 | 312.82 | |
| whole organism · T_AE1 | 1 | 1 | 432.15 | 432.15 | |
| whole organism · T_C3ES | 1 | 1 | 251.99 | 251.99 | |
| whole organism · T_AE2 | 1 | 1 | 535.32 | 535.32 | |
| whole organism · T_AE3 | 1 | 1 | 437.71 | 437.71 | |
| whole organism · T_AES1 | 1 | 1 | 244.54 | 244.54 | |
| whole organism · T_AES2 | 1 | 1 | 255.76 | 255.76 | |
| whole organism · T_AES3 | 1 | 1 | 279.98 | 279.98 | |
| whole organism · T_AAS1 | 1 | 1 | 286.95 | 286.95 | |
| whole organism · T_AAS2 | 1 | 1 | 265.37 | 265.37 | |
| whole organism · T_AAS3 | 1 | 1 | 344.80 | 344.80 | |
| whole organism · T_A1P | 1 | 1 | 239.38 | 239.38 | |
| whole organism · T_A2P | 1 | 1 | 236.96 | 236.96 | |
| whole organism · T_A3P | 1 | 1 | 267.81 | 267.81 | |
| whole organism · T_C1ES | 1 | 1 | 239.29 | 239.29 | |
| whole organism · T_C2ES | 1 | 1 | 238.57 | 238.57 | |
| whole organism · T_C1P | 1 | 1 | 280.08 | 280.08 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR25982246 | whole organism · T_A1ES | whole organism | not recorded | T_A1ES | SRP459341 | 292.90 |
| SRR25982262 | whole organism · T_C3E | whole organism | not recorded | T_C3E | SRP459341 | 427.72 |
| SRR25982274 | whole organism · T_C2P | whole organism | not recorded | T_C2P | SRP459341 | 298.60 |
| SRR25982273 | whole organism · T_A2ES | whole organism | not recorded | T_A2ES | SRP459341 | 261.24 |
| SRR25982272 | whole organism · T_A3ES | whole organism | not recorded | T_A3ES | SRP459341 | 304.79 |
| SRR25982271 | whole organism · T_C1AS | whole organism | not recorded | T_C1AS | SRP459341 | 261.39 |
| SRR25982270 | whole organism · T_C2AS | whole organism | not recorded | T_C2AS | SRP459341 | 276.07 |
| SRR25982269 | whole organism · T_C3AS | whole organism | not recorded | T_C3AS | SRP459341 | 282.77 |
| SRR25982268 | whole organism · T_A1AS | whole organism | not recorded | T_A1AS | SRP459341 | 262.94 |
| SRR25982267 | whole organism · T_A2AS | whole organism | not recorded | T_A2AS | SRP459341 | 261.55 |
| SRR25982266 | whole organism · T_A3AS | whole organism | not recorded | T_A3AS | SRP459341 | 279.44 |
| SRR25982265 | whole organism · T_C1E | whole organism | not recorded | T_C1E | SRP459341 | 366.76 |
| SRR25982264 | whole organism · T_C2E | whole organism | not recorded | T_C2E | SRP459341 | 390.08 |
| SRR25982263 | whole organism · T_C3P | whole organism | not recorded | T_C3P | SRP459341 | 312.82 |
| SRR25982261 | whole organism · T_AE1 | whole organism | not recorded | T_AE1 | SRP459341 | 432.15 |
| SRR25982247 | whole organism · T_C3ES | whole organism | not recorded | T_C3ES | SRP459341 | 251.99 |
| SRR25982260 | whole organism · T_AE2 | whole organism | not recorded | T_AE2 | SRP459341 | 535.32 |
| SRR25982259 | whole organism · T_AE3 | whole organism | not recorded | T_AE3 | SRP459341 | 437.71 |
| SRR25982258 | whole organism · T_AES1 | whole organism | not recorded | T_AES1 | SRP459341 | 244.54 |
| SRR25982257 | whole organism · T_AES2 | whole organism | not recorded | T_AES2 | SRP459341 | 255.76 |
| SRR25982256 | whole organism · T_AES3 | whole organism | not recorded | T_AES3 | SRP459341 | 279.98 |
| SRR25982255 | whole organism · T_AAS1 | whole organism | not recorded | T_AAS1 | SRP459341 | 286.95 |
| SRR25982254 | whole organism · T_AAS2 | whole organism | not recorded | T_AAS2 | SRP459341 | 265.37 |
| SRR25982253 | whole organism · T_AAS3 | whole organism | not recorded | T_AAS3 | SRP459341 | 344.80 |
| SRR25982252 | whole organism · T_A1P | whole organism | not recorded | T_A1P | SRP459341 | 239.38 |
| SRR25982251 | whole organism · T_A2P | whole organism | not recorded | T_A2P | SRP459341 | 236.96 |
| SRR25982250 | whole organism · T_A3P | whole organism | not recorded | T_A3P | SRP459341 | 267.81 |
| SRR25982249 | whole organism · T_C1ES | whole organism | not recorded | T_C1ES | SRP459341 | 239.29 |
| SRR25982248 | whole organism · T_C2ES | whole organism | not recorded | T_C2ES | SRP459341 | 238.57 |
| SRR25982275 | whole organism · T_C1P | whole organism | not recorded | T_C1P | SRP459341 | 280.08 |
Source: CnidoSite RNA-seq expression matrices (ACOER_TPM,
StringTie quantification over 30 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Aurelia coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 7 | evm.model.ptg000013l.1124 | 0.966551465267396 |
| Negatively correlated | 9 | evm.model.ptg000018l.462 | -0.864465482065725 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Aurelia coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
