Genomic Location: chr13:1666435...1694425
NR annotation: XP_002160112.1, radixin [Hydra vulgaris]
Species Aurelia coerulea · all data for this species · gene families
| CDS |
| evm.model.ptg000009l.1070 |
| Transcript |
| evm.model.ptg000009l.1070 |
| Protein |
| evm.model.ptg000009l.1070 |
| UniProt accession | Description |
|---|---|
| P35241 | Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1 |
| Q2HJ49 | Moesin OS=Bos taurus OX=9913 GN=MSN PE=2 SV=3 |
| Q32LP2 | Radixin OS=Bos taurus OX=9913 GN=RDX PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001415 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00769 all species → | ERM_C | Ezrin/radixin/moesin family C terminal | Domain | Interproscan |
| PF00373 all species → | FERM_M | FERM central domain | Domain | Interproscan |
| PF09380 all species → | FERM_C | FERM C-terminal PH-like domain | Domain | Interproscan |
| PF09379 all species → | FERM_N | FERM N-terminal domain | Domain | Interproscan |
| PF20492 all species → | ERM_helical | Ezrin/radixin/moesin, alpha-helical domain | Coiled-coil | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR041789 all species → | Domain | ERM family, FERM domain C-lobe | Interproscan |
| IPR019747 all species → | Conserved_site | FERM conserved site | Interproscan |
| IPR029071 all species → | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR011174 all species → | Family | Ezrin/radixin/moesin | Interproscan |
| IPR014352 all species → | Homologous_superfamily | FERM/acyl-CoA-binding protein superfamily | Interproscan |
| IPR019748 all species → | Domain | FERM central domain | Interproscan |
| IPR011259 all species → | Domain | Ezrin/radixin/moesin, C-terminal | Interproscan |
| IPR019749 all species → | Domain | Band 4.1 domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR018980 all species → | Domain | FERM, C-terminal PH-like domain | Interproscan |
| IPR008954 all species → | Homologous_superfamily | Moesin tail domain superfamily | Interproscan |
| IPR000798 all species → | Family | Ezrin/radixin/moesin-like | Interproscan |
| IPR035963 all species → | Homologous_superfamily | FERM superfamily, second domain | Interproscan |
| IPR018979 all species → | Domain | FERM, N-terminal | Interproscan |
| IPR046810 all species → | Domain | Ezrin/radixin/moesin, alpha-helical domain | Interproscan |
| IPR000299 all species → | Domain | FERM domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23281 all species → | MERLIN/MOESIN/EZRIN/RADIXIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003779 all species → | Molecular Function | actin binding | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0005912 all species → | Cellular Component | adherens junction | Interproscan |
| GO:0008360 all species → | Biological Process | regulation of cell shape | Interproscan |
| GO:0030175 all species → | Cellular Component | filopodium | Interproscan |
| GO:0045177 all species → | Cellular Component | apical part of cell | Interproscan |
| GO:0050839 all species → | Molecular Function | cell adhesion molecule binding | Interproscan |
| GO:1902115 all species → | Biological Process | regulation of organelle assembly | Interproscan |
| GO:1902966 all species → | Biological Process | positive regulation of protein localization to early endosome | Interproscan |
| GO:2000643 all species → | Biological Process | positive regulation of early endosome to late endosome transport | Interproscan |
| GO:0008092 all species → | Molecular Function | cytoskeletal protein binding | Interproscan |
| GO:0005856 all species → | Cellular Component | cytoskeleton | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K05762 | RDX; radixin | - | Exosome | ko04147 | deepkoala |
Transcript abundance of evm.model.ptg000009l.1070 across 30 RNA-seq samples of Aurelia coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
Every sample in this dataset carries its own condition — the source metadata gives each run a distinct treatment label — so this table is effectively a sample list. The per-sample chart below is the informative view here.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · T_A1ES | 1 | 1 | 167.08 | 167.08 | |
| whole organism · T_C3E | 1 | 1 | 139.48 | 139.48 | |
| whole organism · T_C2P | 1 | 1 | 342.40 | 342.40 | |
| whole organism · T_A2ES | 1 | 1 | 184.69 | 184.69 | |
| whole organism · T_A3ES | 1 | 1 | 225.84 | 225.84 | |
| whole organism · T_C1AS | 1 | 1 | 183.60 | 183.60 | |
| whole organism · T_C2AS | 1 | 1 | 181.02 | 181.02 | |
| whole organism · T_C3AS | 1 | 1 | 166.23 | 166.23 | |
| whole organism · T_A1AS | 1 | 1 | 281.97 | 281.97 | |
| whole organism · T_A2AS | 1 | 1 | 259.58 | 259.58 | |
| whole organism · T_A3AS | 1 | 1 | 292.51 | 292.51 | |
| whole organism · T_C1E | 1 | 1 | 122.04 | 122.04 | |
| whole organism · T_C2E | 1 | 1 | 149.43 | 149.43 | |
| whole organism · T_C3P | 1 | 1 | 262.73 | 262.73 | |
| whole organism · T_AE1 | 1 | 1 | 181.19 | 181.19 | |
| whole organism · T_C3ES | 1 | 1 | 192.60 | 192.60 | |
| whole organism · T_AE2 | 1 | 1 | 166.30 | 166.30 | |
| whole organism · T_AE3 | 1 | 1 | 183.41 | 183.41 | |
| whole organism · T_AES1 | 1 | 1 | 293.02 | 293.02 | |
| whole organism · T_AES2 | 1 | 1 | 402.65 | 402.65 | |
| whole organism · T_AES3 | 1 | 1 | 239.89 | 239.89 | |
| whole organism · T_AAS1 | 1 | 1 | 207.28 | 207.28 | |
| whole organism · T_AAS2 | 1 | 1 | 182.02 | 182.02 | |
| whole organism · T_AAS3 | 1 | 1 | 178.67 | 178.67 | |
| whole organism · T_A1P | 1 | 1 | 187.43 | 187.43 | |
| whole organism · T_A2P | 1 | 1 | 191.20 | 191.20 | |
| whole organism · T_A3P | 1 | 1 | 203.36 | 203.36 | |
| whole organism · T_C1ES | 1 | 1 | 183.21 | 183.21 | |
| whole organism · T_C2ES | 1 | 1 | 186.28 | 186.28 | |
| whole organism · T_C1P | 1 | 1 | 239.79 | 239.79 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR25982246 | whole organism · T_A1ES | whole organism | not recorded | T_A1ES | SRP459341 | 167.08 |
| SRR25982262 | whole organism · T_C3E | whole organism | not recorded | T_C3E | SRP459341 | 139.48 |
| SRR25982274 | whole organism · T_C2P | whole organism | not recorded | T_C2P | SRP459341 | 342.40 |
| SRR25982273 | whole organism · T_A2ES | whole organism | not recorded | T_A2ES | SRP459341 | 184.69 |
| SRR25982272 | whole organism · T_A3ES | whole organism | not recorded | T_A3ES | SRP459341 | 225.84 |
| SRR25982271 | whole organism · T_C1AS | whole organism | not recorded | T_C1AS | SRP459341 | 183.60 |
| SRR25982270 | whole organism · T_C2AS | whole organism | not recorded | T_C2AS | SRP459341 | 181.02 |
| SRR25982269 | whole organism · T_C3AS | whole organism | not recorded | T_C3AS | SRP459341 | 166.23 |
| SRR25982268 | whole organism · T_A1AS | whole organism | not recorded | T_A1AS | SRP459341 | 281.97 |
| SRR25982267 | whole organism · T_A2AS | whole organism | not recorded | T_A2AS | SRP459341 | 259.58 |
| SRR25982266 | whole organism · T_A3AS | whole organism | not recorded | T_A3AS | SRP459341 | 292.51 |
| SRR25982265 | whole organism · T_C1E | whole organism | not recorded | T_C1E | SRP459341 | 122.04 |
| SRR25982264 | whole organism · T_C2E | whole organism | not recorded | T_C2E | SRP459341 | 149.43 |
| SRR25982263 | whole organism · T_C3P | whole organism | not recorded | T_C3P | SRP459341 | 262.73 |
| SRR25982261 | whole organism · T_AE1 | whole organism | not recorded | T_AE1 | SRP459341 | 181.19 |
| SRR25982247 | whole organism · T_C3ES | whole organism | not recorded | T_C3ES | SRP459341 | 192.60 |
| SRR25982260 | whole organism · T_AE2 | whole organism | not recorded | T_AE2 | SRP459341 | 166.30 |
| SRR25982259 | whole organism · T_AE3 | whole organism | not recorded | T_AE3 | SRP459341 | 183.41 |
| SRR25982258 | whole organism · T_AES1 | whole organism | not recorded | T_AES1 | SRP459341 | 293.02 |
| SRR25982257 | whole organism · T_AES2 | whole organism | not recorded | T_AES2 | SRP459341 | 402.65 |
| SRR25982256 | whole organism · T_AES3 | whole organism | not recorded | T_AES3 | SRP459341 | 239.89 |
| SRR25982255 | whole organism · T_AAS1 | whole organism | not recorded | T_AAS1 | SRP459341 | 207.28 |
| SRR25982254 | whole organism · T_AAS2 | whole organism | not recorded | T_AAS2 | SRP459341 | 182.02 |
| SRR25982253 | whole organism · T_AAS3 | whole organism | not recorded | T_AAS3 | SRP459341 | 178.67 |
| SRR25982252 | whole organism · T_A1P | whole organism | not recorded | T_A1P | SRP459341 | 187.43 |
| SRR25982251 | whole organism · T_A2P | whole organism | not recorded | T_A2P | SRP459341 | 191.20 |
| SRR25982250 | whole organism · T_A3P | whole organism | not recorded | T_A3P | SRP459341 | 203.36 |
| SRR25982249 | whole organism · T_C1ES | whole organism | not recorded | T_C1ES | SRP459341 | 183.21 |
| SRR25982248 | whole organism · T_C2ES | whole organism | not recorded | T_C2ES | SRP459341 | 186.28 |
| SRR25982275 | whole organism · T_C1P | whole organism | not recorded | T_C1P | SRP459341 | 239.79 |
Source: CnidoSite RNA-seq expression matrices (ACOER_TPM,
StringTie quantification over 30 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Aurelia coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 36 | evm.model.ptg000031l.521 | 0.921464653385792 |
| Negatively correlated | 21 | evm.model.ptg000014l.20 | -0.898929506169232 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Aurelia coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
