Genomic Location: chr13:4470918...4657007
NR annotation: XP_048577837.1, sperm-associated antigen 17 isoform X1 [Nematostella vectensis]
Species Aurelia coerulea · all data for this species · gene families
| CDS |
| evm.model.ptg000009l.969 |
| Transcript |
| evm.model.ptg000009l.969 |
| Protein |
| evm.model.ptg000009l.969 |
| UniProt accession | Description |
|---|---|
| P91620 | Protein still life, isoforms C/SIF type 2 OS=Drosophila melanogaster OX=7227 GN=sif PE=2 SV=2 |
| P91621 | Protein still life, isoform SIF type 1 OS=Drosophila melanogaster OX=7227 GN=sif PE=2 SV=2 |
| Q8IVF5 | Rho guanine nucleotide exchange factor TIAM2 OS=Homo sapiens OX=9606 GN=TIAM2 PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002876 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00595 all species → | PDZ | PDZ domain | Domain | Interproscan |
| PF02196 all species → | RBD | Raf-like Ras-binding domain | Domain | Interproscan |
| PF00621 all species → | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF14874 all species → | PapD-like | Flagellar-associated PapD-like | Domain | Interproscan |
| PF00169 all species → | PH | PH domain | Domain | Interproscan |
| PF00568 all species → | WH1 | WH1 domain | Domain | Interproscan |
| PF18385 all species → | Tiam_CC_Ex | T-lymphoma invasion and metastasis CC-Ex domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001478 all species → | Domain | PDZ domain | Interproscan |
| IPR003116 all species → | Domain | Raf-like Ras-binding | Interproscan |
| IPR026173 all species → | Family | Sperm-associated antigen 17 | Interproscan |
| IPR029071 all species → | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR000219 all species → | Domain | Dbl homology (DH) domain | Interproscan |
| IPR035899 all species → | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| IPR001331 all species → | Conserved_site | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Interproscan |
| IPR000697 all species → | Domain | WH1/EVH1 domain | Interproscan |
| IPR036034 all species → | Homologous_superfamily | PDZ superfamily | Interproscan |
| IPR040655 all species → | Domain | TIAM1, CC-Ex domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21963 all species → | PF6 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0007165 all species → | Biological Process | signal transduction | Interproscan |
| GO:0003351 all species → | Biological Process | epithelial cilium movement involved in extracellular fluid movement | Interproscan |
| GO:1904158 all species → | Biological Process | axonemal central apparatus assembly | Interproscan |
| GO:1990716 all species → | Cellular Component | axonemal central apparatus | Interproscan |
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0035556 all species → | Biological Process | intracellular signal transduction | Interproscan |
evm.model.ptg000009l.969.Transcript abundance of evm.model.ptg000009l.969 across 30 RNA-seq samples of Aurelia coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
Every sample in this dataset carries its own condition — the source metadata gives each run a distinct treatment label — so this table is effectively a sample list. The per-sample chart below is the informative view here.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · T_A1ES | 1 | 1 | 2.12 | 2.12 | |
| whole organism · T_C3E | 1 | 1 | 10.63 | 10.63 | |
| whole organism · T_C2P | 1 | 1 | 2.39 | 2.39 | |
| whole organism · T_A2ES | 1 | 1 | 2.96 | 2.96 | |
| whole organism · T_A3ES | 1 | 1 | 2.68 | 2.68 | |
| whole organism · T_C1AS | 1 | 1 | 3.23 | 3.23 | |
| whole organism · T_C2AS | 1 | 1 | 3.54 | 3.54 | |
| whole organism · T_C3AS | 1 | 1 | 3.73 | 3.73 | |
| whole organism · T_A1AS | 1 | 1 | 2.87 | 2.87 | |
| whole organism · T_A2AS | 1 | 1 | 2.51 | 2.51 | |
| whole organism · T_A3AS | 1 | 1 | 2.46 | 2.46 | |
| whole organism · T_C1E | 1 | 1 | 8.04 | 8.04 | |
| whole organism · T_C2E | 1 | 1 | 6.82 | 6.82 | |
| whole organism · T_C3P | 1 | 1 | 1.33 | 1.33 | |
| whole organism · T_AE1 | 1 | 1 | 17.10 | 17.10 | |
| whole organism · T_C3ES | 1 | 1 | 2.29 | 2.29 | |
| whole organism · T_AE2 | 1 | 1 | 15.78 | 15.78 | |
| whole organism · T_AE3 | 1 | 1 | 12.42 | 12.42 | |
| whole organism · T_AES1 | 1 | 1 | 5.96 | 5.96 | |
| whole organism · T_AES2 | 1 | 1 | 7.13 | 7.13 | |
| whole organism · T_AES3 | 1 | 1 | 4.40 | 4.40 | |
| whole organism · T_AAS1 | 1 | 1 | 8.50 | 8.50 | |
| whole organism · T_AAS2 | 1 | 1 | 9.25 | 9.25 | |
| whole organism · T_AAS3 | 1 | 1 | 8.70 | 8.70 | |
| whole organism · T_A1P | 1 | 1 | 0.92 | 0.92 | |
| whole organism · T_A2P | 1 | 1 | 1.43 | 1.43 | |
| whole organism · T_A3P | 1 | 1 | 1.11 | 1.11 | |
| whole organism · T_C1ES | 1 | 1 | 1.98 | 1.98 | |
| whole organism · T_C2ES | 1 | 1 | 1.63 | 1.63 | |
| whole organism · T_C1P | 1 | 1 | 1.35 | 1.35 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR25982246 | whole organism · T_A1ES | whole organism | not recorded | T_A1ES | SRP459341 | 2.12 |
| SRR25982262 | whole organism · T_C3E | whole organism | not recorded | T_C3E | SRP459341 | 10.63 |
| SRR25982274 | whole organism · T_C2P | whole organism | not recorded | T_C2P | SRP459341 | 2.39 |
| SRR25982273 | whole organism · T_A2ES | whole organism | not recorded | T_A2ES | SRP459341 | 2.96 |
| SRR25982272 | whole organism · T_A3ES | whole organism | not recorded | T_A3ES | SRP459341 | 2.68 |
| SRR25982271 | whole organism · T_C1AS | whole organism | not recorded | T_C1AS | SRP459341 | 3.23 |
| SRR25982270 | whole organism · T_C2AS | whole organism | not recorded | T_C2AS | SRP459341 | 3.54 |
| SRR25982269 | whole organism · T_C3AS | whole organism | not recorded | T_C3AS | SRP459341 | 3.73 |
| SRR25982268 | whole organism · T_A1AS | whole organism | not recorded | T_A1AS | SRP459341 | 2.87 |
| SRR25982267 | whole organism · T_A2AS | whole organism | not recorded | T_A2AS | SRP459341 | 2.51 |
| SRR25982266 | whole organism · T_A3AS | whole organism | not recorded | T_A3AS | SRP459341 | 2.46 |
| SRR25982265 | whole organism · T_C1E | whole organism | not recorded | T_C1E | SRP459341 | 8.04 |
| SRR25982264 | whole organism · T_C2E | whole organism | not recorded | T_C2E | SRP459341 | 6.82 |
| SRR25982263 | whole organism · T_C3P | whole organism | not recorded | T_C3P | SRP459341 | 1.33 |
| SRR25982261 | whole organism · T_AE1 | whole organism | not recorded | T_AE1 | SRP459341 | 17.10 |
| SRR25982247 | whole organism · T_C3ES | whole organism | not recorded | T_C3ES | SRP459341 | 2.29 |
| SRR25982260 | whole organism · T_AE2 | whole organism | not recorded | T_AE2 | SRP459341 | 15.78 |
| SRR25982259 | whole organism · T_AE3 | whole organism | not recorded | T_AE3 | SRP459341 | 12.42 |
| SRR25982258 | whole organism · T_AES1 | whole organism | not recorded | T_AES1 | SRP459341 | 5.96 |
| SRR25982257 | whole organism · T_AES2 | whole organism | not recorded | T_AES2 | SRP459341 | 7.13 |
| SRR25982256 | whole organism · T_AES3 | whole organism | not recorded | T_AES3 | SRP459341 | 4.40 |
| SRR25982255 | whole organism · T_AAS1 | whole organism | not recorded | T_AAS1 | SRP459341 | 8.50 |
| SRR25982254 | whole organism · T_AAS2 | whole organism | not recorded | T_AAS2 | SRP459341 | 9.25 |
| SRR25982253 | whole organism · T_AAS3 | whole organism | not recorded | T_AAS3 | SRP459341 | 8.70 |
| SRR25982252 | whole organism · T_A1P | whole organism | not recorded | T_A1P | SRP459341 | 0.92 |
| SRR25982251 | whole organism · T_A2P | whole organism | not recorded | T_A2P | SRP459341 | 1.43 |
| SRR25982250 | whole organism · T_A3P | whole organism | not recorded | T_A3P | SRP459341 | 1.11 |
| SRR25982249 | whole organism · T_C1ES | whole organism | not recorded | T_C1ES | SRP459341 | 1.98 |
| SRR25982248 | whole organism · T_C2ES | whole organism | not recorded | T_C2ES | SRP459341 | 1.63 |
| SRR25982275 | whole organism · T_C1P | whole organism | not recorded | T_C1P | SRP459341 | 1.35 |
Source: CnidoSite RNA-seq expression matrices (ACOER_TPM,
StringTie quantification over 30 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Aurelia coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 50 | evm.model.ptg000010l.1167 | 0.985138897290073 |
| Negatively correlated | 5 | evm.model.ptg000055l.163 | -0.857523551258665 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Aurelia coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
