Genomic Location: chr21:9687156...9724394
NR annotation: XP_002167606.2, endoplasmic reticulum aminopeptidase 1 isoform X1 [Hydra vulgaris]
Species Aurelia coerulea · all data for this species · gene families
| CDS |
| evm.model.ptg000028l.782 |
| Transcript |
| evm.model.ptg000028l.782 |
| Protein |
| evm.model.ptg000028l.782 |
| UniProt accession | Description |
|---|---|
| A6QPT7 | Endoplasmic reticulum aminopeptidase 2 OS=Bos taurus OX=9913 GN=ERAP2 PE=2 SV=1 |
| D3UW23 | Glutamyl aminopeptidase OS=Bitis rhinoceros OX=715877 PE=1 SV=1 |
| A5HUI5 | Aminopeptidase A OS=Gloydius brevicauda OX=3148161 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000212 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF11838 all species → | ERAP1_C | ERAP1-like C-terminal domain | Domain | Interproscan |
| PF01433 all species → | Peptidase_M1 | Peptidase family M1 domain | Domain | Interproscan |
| PF17900 all species → | Peptidase_M1_N | Peptidase M1 N-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR027268 all species → | Homologous_superfamily | Peptidase M4/M1, CTD superfamily | Interproscan |
| IPR042097 all species → | Homologous_superfamily | Aminopeptidase N-like , N-terminal domain superfamliy | Interproscan |
| IPR050344 all species → | Family | Peptidase M1 family aminopeptidases | Interproscan |
| IPR001930 all species → | Family | Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase | Interproscan |
| IPR024571 all species → | Domain | ERAP1-like C-terminal domain | Interproscan |
| IPR014782 all species → | Domain | Peptidase M1, membrane alanine aminopeptidase | Interproscan |
| IPR034016 all species → | Family | Aminopeptidase N-type | Interproscan |
| IPR045357 all species → | Domain | Aminopeptidase N-like , N-terminal domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11533 all species → | PROTEASE M1 ZINC METALLOPROTEASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| GO:0008270 all species → | Molecular Function | zinc ion binding | Interproscan |
| GO:0042277 all species → | Molecular Function | peptide binding | Interproscan |
| GO:0043171 all species → | Biological Process | peptide catabolic process | Interproscan |
| GO:0070006 all species → | Molecular Function | metalloaminopeptidase activity | Interproscan |
| GO:0008237 all species → | Molecular Function | metallopeptidase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11141 | ENPEP, CD249; glutamyl aminopeptidase | EC:3.4.11.7 | CD molecules | ko04090 | deepkoala |
Transcript abundance of evm.model.ptg000028l.782 across 30 RNA-seq samples of Aurelia coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
Every sample in this dataset carries its own condition — the source metadata gives each run a distinct treatment label — so this table is effectively a sample list. The per-sample chart below is the informative view here.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · T_A1ES | 1 | 1 | 3.87 | 3.87 | |
| whole organism · T_C3E | 1 | 1 | 11.31 | 11.31 | |
| whole organism · T_C2P | 1 | 1 | 4.97 | 4.97 | |
| whole organism · T_A2ES | 1 | 1 | 3.70 | 3.70 | |
| whole organism · T_A3ES | 1 | 1 | 3.79 | 3.79 | |
| whole organism · T_C1AS | 1 | 1 | 8.55 | 8.55 | |
| whole organism · T_C2AS | 1 | 1 | 13.23 | 13.23 | |
| whole organism · T_C3AS | 1 | 1 | 9.89 | 9.89 | |
| whole organism · T_A1AS | 1 | 1 | 29.55 | 29.55 | |
| whole organism · T_A2AS | 1 | 1 | 19.20 | 19.20 | |
| whole organism · T_A3AS | 1 | 1 | 28.31 | 28.31 | |
| whole organism · T_C1E | 1 | 1 | 10.43 | 10.43 | |
| whole organism · T_C2E | 1 | 1 | 4.57 | 4.57 | |
| whole organism · T_C3P | 1 | 1 | 3.06 | 3.06 | |
| whole organism · T_AE1 | 1 | 1 | 49.22 | 49.22 | |
| whole organism · T_C3ES | 1 | 1 | 10.41 | 10.41 | |
| whole organism · T_AE2 | 1 | 1 | 30.78 | 30.78 | |
| whole organism · T_AE3 | 1 | 1 | 25.23 | 25.23 | |
| whole organism · T_AES1 | 1 | 1 | 29.95 | 29.95 | |
| whole organism · T_AES2 | 1 | 1 | 29.26 | 29.26 | |
| whole organism · T_AES3 | 1 | 1 | 25.82 | 25.82 | |
| whole organism · T_AAS1 | 1 | 1 | 33.81 | 33.81 | |
| whole organism · T_AAS2 | 1 | 1 | 31.20 | 31.20 | |
| whole organism · T_AAS3 | 1 | 1 | 35.00 | 35.00 | |
| whole organism · T_A1P | 1 | 1 | 0.48 | 0.48 | |
| whole organism · T_A2P | 1 | 1 | 0.24 | 0.24 | |
| whole organism · T_A3P | 1 | 1 | 0.17 | 0.17 | |
| whole organism · T_C1ES | 1 | 1 | 5.78 | 5.78 | |
| whole organism · T_C2ES | 1 | 1 | 12.94 | 12.94 | |
| whole organism · T_C1P | 1 | 1 | 1.95 | 1.95 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR25982246 | whole organism · T_A1ES | whole organism | not recorded | T_A1ES | SRP459341 | 3.87 |
| SRR25982262 | whole organism · T_C3E | whole organism | not recorded | T_C3E | SRP459341 | 11.31 |
| SRR25982274 | whole organism · T_C2P | whole organism | not recorded | T_C2P | SRP459341 | 4.97 |
| SRR25982273 | whole organism · T_A2ES | whole organism | not recorded | T_A2ES | SRP459341 | 3.70 |
| SRR25982272 | whole organism · T_A3ES | whole organism | not recorded | T_A3ES | SRP459341 | 3.79 |
| SRR25982271 | whole organism · T_C1AS | whole organism | not recorded | T_C1AS | SRP459341 | 8.55 |
| SRR25982270 | whole organism · T_C2AS | whole organism | not recorded | T_C2AS | SRP459341 | 13.23 |
| SRR25982269 | whole organism · T_C3AS | whole organism | not recorded | T_C3AS | SRP459341 | 9.89 |
| SRR25982268 | whole organism · T_A1AS | whole organism | not recorded | T_A1AS | SRP459341 | 29.55 |
| SRR25982267 | whole organism · T_A2AS | whole organism | not recorded | T_A2AS | SRP459341 | 19.20 |
| SRR25982266 | whole organism · T_A3AS | whole organism | not recorded | T_A3AS | SRP459341 | 28.31 |
| SRR25982265 | whole organism · T_C1E | whole organism | not recorded | T_C1E | SRP459341 | 10.43 |
| SRR25982264 | whole organism · T_C2E | whole organism | not recorded | T_C2E | SRP459341 | 4.57 |
| SRR25982263 | whole organism · T_C3P | whole organism | not recorded | T_C3P | SRP459341 | 3.06 |
| SRR25982261 | whole organism · T_AE1 | whole organism | not recorded | T_AE1 | SRP459341 | 49.22 |
| SRR25982247 | whole organism · T_C3ES | whole organism | not recorded | T_C3ES | SRP459341 | 10.41 |
| SRR25982260 | whole organism · T_AE2 | whole organism | not recorded | T_AE2 | SRP459341 | 30.78 |
| SRR25982259 | whole organism · T_AE3 | whole organism | not recorded | T_AE3 | SRP459341 | 25.23 |
| SRR25982258 | whole organism · T_AES1 | whole organism | not recorded | T_AES1 | SRP459341 | 29.95 |
| SRR25982257 | whole organism · T_AES2 | whole organism | not recorded | T_AES2 | SRP459341 | 29.26 |
| SRR25982256 | whole organism · T_AES3 | whole organism | not recorded | T_AES3 | SRP459341 | 25.82 |
| SRR25982255 | whole organism · T_AAS1 | whole organism | not recorded | T_AAS1 | SRP459341 | 33.81 |
| SRR25982254 | whole organism · T_AAS2 | whole organism | not recorded | T_AAS2 | SRP459341 | 31.20 |
| SRR25982253 | whole organism · T_AAS3 | whole organism | not recorded | T_AAS3 | SRP459341 | 35.00 |
| SRR25982252 | whole organism · T_A1P | whole organism | not recorded | T_A1P | SRP459341 | 0.48 |
| SRR25982251 | whole organism · T_A2P | whole organism | not recorded | T_A2P | SRP459341 | 0.24 |
| SRR25982250 | whole organism · T_A3P | whole organism | not recorded | T_A3P | SRP459341 | 0.17 |
| SRR25982249 | whole organism · T_C1ES | whole organism | not recorded | T_C1ES | SRP459341 | 5.78 |
| SRR25982248 | whole organism · T_C2ES | whole organism | not recorded | T_C2ES | SRP459341 | 12.94 |
| SRR25982275 | whole organism · T_C1P | whole organism | not recorded | T_C1P | SRP459341 | 1.95 |
Source: CnidoSite RNA-seq expression matrices (ACOER_TPM,
StringTie quantification over 30 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Aurelia coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 35 | evm.model.ptg000031l.421 | 0.983666238547311 |
| Negatively correlated | 3 | evm.model.ptg000012l.793 | -0.846069468792924 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Aurelia coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
