Genomic Location: chr21:14824218...14913118
NR annotation: XP_002169426.4, protein FAM135A [Hydra vulgaris]
Species Aurelia coerulea · all data for this species · gene families
| CDS |
| evm.model.ptg000028l.998 |
| Transcript |
| evm.model.ptg000028l.998 |
| Protein |
| evm.model.ptg000028l.998 |
| UniProt accession | Description |
|---|---|
| Q641I1 | Protein FAM135B OS=Xenopus laevis OX=8355 GN=fam135b PE=2 SV=1 |
| Q5RA75 | Protein FAM135A OS=Pongo abelii OX=9601 GN=FAM135A PE=2 SV=1 |
| Q9DAI6 | Protein FAM135B OS=Mus musculus OX=10090 GN=Fam135b PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004845 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF14523 all species → | Syntaxin_2 | Syntaxin-like protein | Domain | Interproscan |
| PF00060 all species → | Lig_chan | Ligand-gated ion channel | Family | Interproscan |
| PF07885 all species → | Ion_trans_2 | Ion channel | Family | Interproscan |
| PF00090 all species → | TSP_1 | Thrombospondin type 1 domain | Domain | Interproscan |
| PF05057 all species → | DUF676 | Putative serine esterase (DUF676) | Family | Interproscan |
| PF05739 all species → | SNARE | SNARE domain | Family | Interproscan |
| PF12394 all species → | DUF3657 | Protein FAM135 | Family | Interproscan |
| PF00041 all species → | fn3 | Fibronectin type III domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006012 all species → | Conserved_site | Syntaxin/epimorphin, conserved site | Interproscan |
| IPR000884 all species → | Repeat | Thrombospondin type-1 (TSP1) repeat | Interproscan |
| IPR006011 all species → | Domain | Syntaxin, N-terminal domain | Interproscan |
| IPR001320 all species → | Domain | Ionotropic glutamate receptor, C-terminal | Interproscan |
| IPR036116 all species → | Homologous_superfamily | Fibronectin type III superfamily | Interproscan |
| IPR003961 all species → | Domain | Fibronectin type III | Interproscan |
| IPR036383 all species → | Homologous_superfamily | Thrombospondin type-1 (TSP1) repeat superfamily | Interproscan |
| IPR013099 all species → | Domain | Potassium channel domain | Interproscan |
| IPR029058 all species → | Homologous_superfamily | Alpha/Beta hydrolase fold | Interproscan |
| IPR000727 all species → | Domain | Target SNARE coiled-coil homology domain | Interproscan |
| IPR000082 all species → | Domain | SEA domain | Interproscan |
| IPR013783 all species → | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR010989 all species → | Homologous_superfamily | SNARE | Interproscan |
| IPR007751 all species → | Domain | Domain of unknown function DUF676, lipase-like | Interproscan |
| IPR022122 all species → | Family | Protein FAM135 | Interproscan |
| IPR044294 all species → | Family | Lipase-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12482 all species → | UNCHARACTERIZED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005484 all species → | Molecular Function | SNAP receptor activity | Interproscan |
| GO:0006886 all species → | Biological Process | intracellular protein transport | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0015276 all species → | Molecular Function | ligand-gated monoatomic ion channel activity | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0016192 all species → | Biological Process | vesicle-mediated transport | Interproscan |
| GO:0044255 all species → | Biological Process | obsolete cellular lipid metabolic process | Interproscan |
evm.model.ptg000028l.998.Transcript abundance of evm.model.ptg000028l.998 across 30 RNA-seq samples of Aurelia coerulea. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
Every sample in this dataset carries its own condition — the source metadata gives each run a distinct treatment label — so this table is effectively a sample list. The per-sample chart below is the informative view here.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole organism · T_A1ES | 1 | 1 | 0.48 | 0.48 | |
| whole organism · T_C3E | 1 | 1 | 2.10 | 2.10 | |
| whole organism · T_C2P | 1 | 1 | 0.47 | 0.47 | |
| whole organism · T_A2ES | 1 | 1 | 1.22 | 1.22 | |
| whole organism · T_A3ES | 1 | 1 | 0.99 | 0.99 | |
| whole organism · T_C1AS | 1 | 1 | 0.54 | 0.54 | |
| whole organism · T_C2AS | 1 | 1 | 0.99 | 0.99 | |
| whole organism · T_C3AS | 1 | 1 | 0.62 | 0.62 | |
| whole organism · T_A1AS | 1 | 1 | 2.16 | 2.16 | |
| whole organism · T_A2AS | 1 | 1 | 1.38 | 1.38 | |
| whole organism · T_A3AS | 1 | 1 | 1.91 | 1.91 | |
| whole organism · T_C1E | 1 | 1 | 1.59 | 1.59 | |
| whole organism · T_C2E | 1 | 1 | 1.66 | 1.66 | |
| whole organism · T_C3P | 1 | 1 | 0.43 | 0.43 | |
| whole organism · T_AE1 | 1 | 1 | 4.04 | 4.04 | |
| whole organism · T_C3ES | 1 | 1 | 0.65 | 0.65 | |
| whole organism · T_AE2 | 1 | 1 | 4.44 | 4.44 | |
| whole organism · T_AE3 | 1 | 1 | 3.78 | 3.78 | |
| whole organism · T_AES1 | 1 | 1 | 3.24 | 3.24 | |
| whole organism · T_AES2 | 1 | 1 | 4.36 | 4.36 | |
| whole organism · T_AES3 | 1 | 1 | 2.32 | 2.32 | |
| whole organism · T_AAS1 | 1 | 1 | 2.80 | 2.80 | |
| whole organism · T_AAS2 | 1 | 1 | 2.57 | 2.57 | |
| whole organism · T_AAS3 | 1 | 1 | 1.92 | 1.92 | |
| whole organism · T_A1P | 1 | 1 | 0.08 | 0.08 | |
| whole organism · T_A2P | 1 | 1 | 0.15 | 0.15 | |
| whole organism · T_A3P | 1 | 1 | 0.19 | 0.19 | |
| whole organism · T_C1ES | 1 | 1 | 0.63 | 0.63 | |
| whole organism · T_C2ES | 1 | 1 | 0.63 | 0.63 | |
| whole organism · T_C1P | 1 | 1 | 0.12 | 0.12 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR25982246 | whole organism · T_A1ES | whole organism | not recorded | T_A1ES | SRP459341 | 0.48 |
| SRR25982262 | whole organism · T_C3E | whole organism | not recorded | T_C3E | SRP459341 | 2.10 |
| SRR25982274 | whole organism · T_C2P | whole organism | not recorded | T_C2P | SRP459341 | 0.47 |
| SRR25982273 | whole organism · T_A2ES | whole organism | not recorded | T_A2ES | SRP459341 | 1.22 |
| SRR25982272 | whole organism · T_A3ES | whole organism | not recorded | T_A3ES | SRP459341 | 0.99 |
| SRR25982271 | whole organism · T_C1AS | whole organism | not recorded | T_C1AS | SRP459341 | 0.54 |
| SRR25982270 | whole organism · T_C2AS | whole organism | not recorded | T_C2AS | SRP459341 | 0.99 |
| SRR25982269 | whole organism · T_C3AS | whole organism | not recorded | T_C3AS | SRP459341 | 0.62 |
| SRR25982268 | whole organism · T_A1AS | whole organism | not recorded | T_A1AS | SRP459341 | 2.16 |
| SRR25982267 | whole organism · T_A2AS | whole organism | not recorded | T_A2AS | SRP459341 | 1.38 |
| SRR25982266 | whole organism · T_A3AS | whole organism | not recorded | T_A3AS | SRP459341 | 1.91 |
| SRR25982265 | whole organism · T_C1E | whole organism | not recorded | T_C1E | SRP459341 | 1.59 |
| SRR25982264 | whole organism · T_C2E | whole organism | not recorded | T_C2E | SRP459341 | 1.66 |
| SRR25982263 | whole organism · T_C3P | whole organism | not recorded | T_C3P | SRP459341 | 0.43 |
| SRR25982261 | whole organism · T_AE1 | whole organism | not recorded | T_AE1 | SRP459341 | 4.04 |
| SRR25982247 | whole organism · T_C3ES | whole organism | not recorded | T_C3ES | SRP459341 | 0.65 |
| SRR25982260 | whole organism · T_AE2 | whole organism | not recorded | T_AE2 | SRP459341 | 4.44 |
| SRR25982259 | whole organism · T_AE3 | whole organism | not recorded | T_AE3 | SRP459341 | 3.78 |
| SRR25982258 | whole organism · T_AES1 | whole organism | not recorded | T_AES1 | SRP459341 | 3.24 |
| SRR25982257 | whole organism · T_AES2 | whole organism | not recorded | T_AES2 | SRP459341 | 4.36 |
| SRR25982256 | whole organism · T_AES3 | whole organism | not recorded | T_AES3 | SRP459341 | 2.32 |
| SRR25982255 | whole organism · T_AAS1 | whole organism | not recorded | T_AAS1 | SRP459341 | 2.80 |
| SRR25982254 | whole organism · T_AAS2 | whole organism | not recorded | T_AAS2 | SRP459341 | 2.57 |
| SRR25982253 | whole organism · T_AAS3 | whole organism | not recorded | T_AAS3 | SRP459341 | 1.92 |
| SRR25982252 | whole organism · T_A1P | whole organism | not recorded | T_A1P | SRP459341 | 0.08 |
| SRR25982251 | whole organism · T_A2P | whole organism | not recorded | T_A2P | SRP459341 | 0.15 |
| SRR25982250 | whole organism · T_A3P | whole organism | not recorded | T_A3P | SRP459341 | 0.19 |
| SRR25982249 | whole organism · T_C1ES | whole organism | not recorded | T_C1ES | SRP459341 | 0.63 |
| SRR25982248 | whole organism · T_C2ES | whole organism | not recorded | T_C2ES | SRP459341 | 0.63 |
| SRR25982275 | whole organism · T_C1P | whole organism | not recorded | T_C1P | SRP459341 | 0.12 |
Source: CnidoSite RNA-seq expression matrices (ACOER_TPM,
StringTie quantification over 30 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Aurelia coerulea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 54 | evm.model.ptg000003l.109 | 0.986781822010677 |
| Negatively correlated | 3 | evm.model.ptg000020l.49 | -0.858063123925942 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Aurelia coerulea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
