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Support counts the member genes carrying the term. % of genes is that count over all 64 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13954 | IRE1-RELATED | 53 / 64 | 82.8% | 94.6% of 56 | ≥80% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 53 / 64 | 82.8% | 93.0% of 57 | ≥80% support |
| Pfam | PF06479 | Ribonuc_2-5A — Ribonuclease 2-5A | 52 / 64 | 81.3% | 91.2% of 57 | ≥80% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 54 / 64 | 84.4% | 94.7% of 57 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 54 / 64 | 84.4% | 94.7% of 57 | ≥80% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 54 / 64 | 84.4% | 94.7% of 57 | ≥80% support |
| GO | GO:0004521 Molecular Function | RNA endonuclease activity | 53 / 64 | 82.8% | 93.0% of 57 | ≥80% support |
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 53 / 64 | 82.8% | 93.0% of 57 | ≥80% support |
| GO | GO:0030968 Biological Process | endoplasmic reticulum unfolded protein response | 53 / 64 | 82.8% | 93.0% of 57 | ≥80% support |
| GO | GO:0036498 Biological Process | IRE1-mediated unfolded protein response | 53 / 64 | 82.8% | 93.0% of 57 | ≥80% support |
| GO | GO:0051082 Molecular Function | unfolded protein binding | 53 / 64 | 82.8% | 93.0% of 57 | ≥80% support |
| GO | GO:0070059 Biological Process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 53 / 64 | 82.8% | 93.0% of 57 | ≥80% support |
| GO | GO:1990604 Cellular Component | IRE1-TRAF2-ASK1 complex | 53 / 64 | 82.8% | 93.0% of 57 | ≥80% support |
| GO | GO:0004540 Molecular Function | RNA nuclease activity | 52 / 64 | 81.3% | 91.2% of 57 | ≥80% support |
| GO | GO:0006397 Biological Process | mRNA processing | 52 / 64 | 81.3% | 91.2% of 57 | ≥80% support |
| Pfam | PF13855 | LRR_8 — Leucine rich repeat | 49 / 64 | 76.6% | 86.0% of 57 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 49 / 64 | 76.6% | 86.0% of 57 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora awi | aawi_s0004.g206.t1 | XP_044174566.1 | serine/threonine-protein kinase/endoribonuclease IRE2-like [Acropora millepora] | Q9EQY0 Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Mus | JBrowse |
