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Support counts the member genes carrying the term. % of genes is that count over all 924 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13954 | IRE1-RELATED | 498 / 924 | 53.9% | 59.2% of 841 | ≥50% support |
| Pfam | PF00069 | Pkinase — Protein kinase domain | 728 / 924 | 78.8% | 86.7% of 840 | ≥50% support |
| Pfam | PF06479 | Ribonuc_2-5A — Ribonuclease 2-5A | 618 / 924 | 66.9% | 73.6% of 840 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 739 / 924 | 80.0% | 86.7% of 852 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 739 / 924 | 80.0% | 86.7% of 852 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 739 / 924 | 80.0% | 86.7% of 852 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 648 / 924 | 70.1% | 76.1% of 852 | ≥50% support |
| GO | GO:0004540 Molecular Function | RNA nuclease activity | 623 / 924 | 67.4% | 73.1% of 852 | ≥50% support |
| GO | GO:0006397 Biological Process | mRNA processing | 621 / 924 | 67.2% | 72.9% of 852 | ≥50% support |
| GO | GO:0004674 Molecular Function | protein serine/threonine kinase activity | 507 / 924 | 54.9% | 59.5% of 852 | ≥50% support |
| GO | GO:0004521 Molecular Function | RNA endonuclease activity | 498 / 924 | 53.9% | 58.5% of 852 | ≥50% support |
| GO | GO:0030968 Biological Process | endoplasmic reticulum unfolded protein response | 498 / 924 | 53.9% | 58.5% of 852 | ≥50% support |
| GO | GO:0036498 Biological Process | IRE1-mediated unfolded protein response | 467 / 924 | 50.5% | 54.8% of 852 | ≥50% support |
| GO | GO:0051082 Molecular Function | unfolded protein binding | 467 / 924 | 50.5% | 54.8% of 852 | ≥50% support |
| GO | GO:0070059 Biological Process | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | 467 / 924 | 50.5% | 54.8% of 852 | ≥50% support |
| GO | GO:1990604 Cellular Component | IRE1-TRAF2-ASK1 complex | 467 / 924 | 50.5% | 54.8% of 852 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinia equina | EGACTEQ4350000061-PA | XP_031569646.1 | uncharacterized protein LOC116304123 [Actinia tenebrosa] | Q09499 Serine/threonine-protein kinase/endoribonuclease ire-1 OS=Ca | JBrowse |
| Actinia equina | EGACTEQ4350000063-PA | XP_031569190.1 | uncharacterized protein LOC116303744 isoform X1 [Actinia tenebrosa] | P54685 Cyclin-dependent kinase 7 OS=Dictyostelium discoideum OX=446 | JBrowse |
| Actinia equina | EGACTEQ4350000587-PA | XP_031549468.1 | uncharacterized protein LOC116287002 [Actinia tenebrosa] | Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b OS=Ar | JBrowse |
| Actinia equina | EGACTEQ4350001840-PA | XP_031552724.1 | uncharacterized protein LOC116289918 [Actinia tenebrosa] | Q09499 Serine/threonine-protein kinase/endoribonuclease ire-1 OS=Ca | JBrowse |
| Actinia equina | EGACTEQ4350002567-PA | XP_031574968.1 | uncharacterized protein LOC116308632 [Actinia tenebrosa] | Q55GJ2 Probable serine/threonine-protein kinase ireA OS=Dictyosteli | JBrowse |
| Actinia equina | EGACTEQ4350003469-PA | XP_031571107.1 | uncharacterized protein LOC116305352 isoform X2 [Actinia tenebrosa] | – | JBrowse |
| Actinia equina | EGACTEQ4350004776-PA | XP_031560808.1 | uncharacterized protein LOC116296842 [Actinia tenebrosa] | Q557G1 Probable serine/threonine-protein kinase irlB OS=Dictyosteli | JBrowse |
| Actinia equina | EGACTEQ4350005045-PA | XP_031571106.1 | uncharacterized protein LOC116305352 isoform X1 [Actinia tenebrosa] | Q93VJ2 Serine/threonine-protein kinase/endoribonuclease IRE1b OS=Ar | JBrowse |
| Actinia equina | EGACTEQ4350006693-PA | XP_031566415.1 | uncharacterized protein LOC116301484 [Actinia tenebrosa] | O94537 Sensor for unfolded proteins in the ER ire1 OS=Schizosacchar | JBrowse |
| Actinia equina | EGACTEQ4350006937-PA | XP_031575328.1 | ankyrin repeat domain-containing protein 50-like [Actinia tenebrosa] | – | JBrowse |
| Actinia equina | EGACTEQ4350007621-PA | XP_031575198.1 | uncharacterized protein LOC116308828 [Actinia tenebrosa] | O94537 Sensor for unfolded proteins in the ER ire1 OS=Schizosacchar | JBrowse |
| Actinia equina | EGACTEQ4350008945-PA | XP_031574968.1 | uncharacterized protein LOC116308632 [Actinia tenebrosa] | Q55GJ2 Probable serine/threonine-protein kinase ireA OS=Dictyosteli | JBrowse |
| Actinia equina | EGACTEQ4350009966-PA | XP_031552724.1 | uncharacterized protein LOC116289918 [Actinia tenebrosa] | – | JBrowse |
| Actinia equina | EGACTEQ4350010877-PA | XP_031570035.1 | LOW QUALITY PROTEIN: probable serine/threonine-protein kinase irlF [Actinia tenebrosa] | O94537 Sensor for unfolded proteins in the ER ire1 OS=Schizosacchar | JBrowse |
| Actinia equina | EGACTEQ4350011441-PA | XP_031559807.1 | uncharacterized protein LOC116295985 [Actinia tenebrosa] | Q9Z2E3 Serine/threonine-protein kinase/endoribonuclease IRE2 OS=Mus | JBrowse |
| Actinia equina | EGACTEQ4350011441-PB | XP_031559807.1 | uncharacterized protein LOC116295985 [Actinia tenebrosa] | Q9Z2E3 Serine/threonine-protein kinase/endoribonuclease IRE2 OS=Mus | JBrowse |
| Actinia equina | EGACTEQ4350011490-PA | XP_031571107.1 | uncharacterized protein LOC116305352 isoform X2 [Actinia tenebrosa] | Q09499 Serine/threonine-protein kinase/endoribonuclease ire-1 OS=Ca | JBrowse |
| Actinia equina | EGACTEQ4350012495-PA | XP_031549468.1 | uncharacterized protein LOC116287002 [Actinia tenebrosa] | P32361 Serine/threonine-protein kinase/endoribonuclease IRE1 OS=Sac | JBrowse |
| Actinia equina | EGACTEQ4350012966-PA | XP_031568178.1 | calcium/calmodulin-dependent protein kinase cmkA-like [Actinia tenebrosa] | Q00771 Calcium/calmodulin-dependent protein kinase cmkA OS=Emericel | JBrowse |
| Actinia equina | EGACTEQ4350015908-PA | XP_031571106.1 | uncharacterized protein LOC116305352 isoform X1 [Actinia tenebrosa] | – | JBrowse |
