Gene Family

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Member genes
2,575
Species
145
Sequences
2,575
Best annotation support
90.7%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 90.7% of the 2,575 members.

Support counts the member genes carrying the term. % of genes is that count over all 2,575 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF00010HLH — Helix-loop-helix DNA-binding domain2335 / 2,57590.7%99.9%
of 2,337
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity2337 / 2,57590.8%100.0%
of 2,338
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific2321 / 2,57590.1%99.3%
of 2,338
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II2156 / 2,57583.7%92.2%
of 2,338
≥80% support
PANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1851 / 2,57571.9%79.7%
of 2,324
≥50% support
GOGO:0000977
Molecular Function
RNA polymerase II transcription regulatory region sequence-specific DNA binding1851 / 2,57571.9%79.2%
of 2,338
≥50% support
GOGO:0032502
Biological Process
developmental process1851 / 2,57571.9%79.2%
of 2,338
≥50% support
📊 Total members in OG0000221: 16 (filtered to AIDSS · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Alvinactis idsseensis sp. Nov.alvinactis_v1_g1712XP_031572700.1twist-related protein-like [Actinia tenebrosa]P13903
Twist-related protein OS=Xenopus laevis OX=8355 GN=twist1 PE
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g1713XP_020892182.1transcription factor 15 [Exaiptasia diaphana]P79782
Transcription factor 15 OS=Gallus gallus OX=9031 GN=TCF15 PE
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g17141KXJ16510.1Protein atonal-like 8 [Exaiptasia diaphana]Q96SQ7
Transcription factor ATOH8 OS=Homo sapiens OX=9606 GN=ATOH8
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g1715XP_020892151.1transcription factor 15 [Exaiptasia diaphana]Q6QHK4
Factor in the germline alpha OS=Homo sapiens OX=9606 GN=FIGL
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g1716XP_020892262.1protein atonal homolog 7-A-like [Exaiptasia diaphana]–JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g1718XP_020892248.1protein atonal homolog 1 [Exaiptasia diaphana]Q15784
Neurogenic differentiation factor 2 OS=Homo sapiens OX=9606
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g20640XP_031550044.1heart- and neural crest derivatives-expressed protein 2-like [Actinia tenebrosa]Q90690
Heart- and neural crest derivatives-expressed protein 2 OS=G
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g21321XP_020896299.1twist-related protein 2-like [Exaiptasia diaphana]P24899
T-cell acute lymphocytic leukemia protein 1 homolog OS=Gallu
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g21322KXJ16711.1T-cell acute lymphocytic leukemia protein 1-like [Exaiptasia diaphana]Q90YI8
T-cell acute lymphocytic leukemia protein 1 OS=Takifugu rubr
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g21323XP_020896293.1T-cell acute lymphocytic leukemia protein 1 homolog [Exaiptasia diaphana]Q66HH3
Protein lyl-1 OS=Rattus norvegicus OX=10116 GN=Lyl1 PE=2 SV=
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g29540XP_028516865.1achaete-scute homolog 1a-like [Exaiptasia diaphana]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g29575XP_020909828.1achaete-scute homolog 2 [Exaiptasia diaphana]Q06234
Achaete-scute homolog 1 OS=Xenopus laevis OX=8355 GN=ascl1 P
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g29586XP_020907878.1helix-loop-helix protein 2 [Exaiptasia diaphana]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g29743XP_020911354.1achaete-scute homolog 4 [Exaiptasia diaphana]Q6XD76
Achaete-scute homolog 4 OS=Homo sapiens OX=9606 GN=ASCL4 PE=
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g31XP_020917318.1pancreas transcription factor 1 subunit alpha [Exaiptasia diaphana]Q7ZSX3
Pancreas transcription factor 1 subunit alpha OS=Danio rerio
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g32XP_031560876.1pancreas transcription factor 1 subunit alpha-like [Actinia tenebrosa]Q9QX98
Pancreas transcription factor 1 subunit alpha OS=Mus musculu
JBrowse
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