Gene Family

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Member genes
1,293
Species
144
Sequences
1,293
Best annotation support
89.3%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 89.3% of the 1,293 members.

Support counts the member genes carrying the term. % of genes is that count over all 1,293 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR10985BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED1155 / 1,29389.3%99.9%
of 1,156
≥80% support
PfamPF00010HLH — Helix-loop-helix DNA-binding domain1131 / 1,29387.5%97.1%
of 1,165
≥80% support
GOGO:0005634
Cellular Component
nucleus1156 / 1,29389.4%98.1%
of 1,179
≥80% support
GOGO:0000978
Molecular Function
RNA polymerase II cis-regulatory region sequence-specific DNA binding1155 / 1,29389.3%98.0%
of 1,179
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific1155 / 1,29389.3%98.0%
of 1,179
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II1155 / 1,29389.3%98.0%
of 1,179
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity1154 / 1,29389.3%97.9%
of 1,179
≥80% support
GOGO:0009952
Biological Process
anterior/posterior pattern specification1150 / 1,29388.9%97.5%
of 1,179
≥80% support
GOGO:0050767
Biological Process
regulation of neurogenesis1150 / 1,29388.9%97.5%
of 1,179
≥80% support
PfamPF07527Hairy_orange — Hairy Orange678 / 1,29352.4%58.2%
of 1,165
≥50% support
GOGO:0003677
Molecular Function
DNA binding716 / 1,29355.4%60.7%
of 1,179
≥50% support
GOGO:0006355
Biological Process
regulation of DNA-templated transcription715 / 1,29355.3%60.6%
of 1,179
≥50% support
KEGGK06054HES1 — DNA repair and recombination proteins756 / 1,29358.5%97.2%
of 778
≥50% support
📊 Total members in OG0000541: 7 (filtered to AIDSS · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Alvinactis idsseensis sp. Nov.alvinactis_v1_g23813XP_020894157.1transcription factor HES-1-A [Exaiptasia diaphana]Q14469
Transcription factor HES-1 OS=Homo sapiens OX=9606 GN=HES1 P
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g30659KXJ20177.1Enhancer of split mdelta protein [Exaiptasia diaphana]Q01071
Enhancer of split mdelta protein OS=Drosophila melanogaster
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g30664XP_020906375.1enhancer of split m8 protein [Exaiptasia diaphana]P13096
Enhancer of split m5 protein OS=Drosophila melanogaster OX=7
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g30678XP_020906300.1transcription factor HES-2 [Exaiptasia diaphana]O57337
Transcription factor HES-1 OS=Gallus gallus OX=9031 GN=HES1
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g30679XP_020906311.2uncharacterized protein LOC110244444 [Exaiptasia diaphana]Q3ZBG4
Transcription factor HES-1 OS=Bos taurus OX=9913 GN=HES1 PE=
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g30680XP_020906316.1transcription factor HES-1 [Exaiptasia diaphana]Q8AVU4
Transcription factor HES-1-B OS=Xenopus laevis OX=8355 GN=he
JBrowse
Alvinactis idsseensis sp. Nov.alvinactis_v1_g30682XP_020906314.1transcription factor HES-2 [Exaiptasia diaphana]Q90Z12
Transcription factor HES-4-A OS=Xenopus laevis OX=8355 GN=he
JBrowse
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