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This orthogroup contains 5,156 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 5,156 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR18945 | NEUROTRANSMITTER GATED ION CHANNEL | 4668 / 5,156 | 90.5% | 99.9% of 4,674 | ≥80% support |
| Pfam | PF02931 | Neur_chan_LBD — Neurotransmitter-gated ion-channel ligand binding domain | 4502 / 5,156 | 87.3% | 95.2% of 4,727 | ≥80% support |
| Pfam | PF02932 | Neur_chan_memb — Neurotransmitter-gated ion-channel transmembrane region | 4371 / 5,156 | 84.8% | 92.5% of 4,727 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 4779 / 5,156 | 92.7% | 100.0% of 4,779 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 4779 / 5,156 | 92.7% | 100.0% of 4,779 | ≥80% support |
| GO | GO:0005216 Molecular Function | monoatomic ion channel activity | 4713 / 5,156 | 91.4% | 98.6% of 4,779 | ≥80% support |
| GO | GO:0034220 Biological Process | monoatomic ion transmembrane transport | 4712 / 5,156 | 91.4% | 98.6% of 4,779 | ≥80% support |
| GO | GO:0004888 Molecular Function | transmembrane signaling receptor activity | 4712 / 5,156 | 91.4% | 98.6% of 4,779 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 4669 / 5,156 | 90.6% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0007268 Biological Process | chemical synaptic transmission | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0030594 Molecular Function | neurotransmitter receptor activity | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0042391 Biological Process | regulation of membrane potential | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0043005 Cellular Component | neuron projection | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0045202 Cellular Component | synapse | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0050877 Biological Process | nervous system process | 4668 / 5,156 | 90.5% | 97.7% of 4,779 | ≥80% support |
| GO | GO:0005230 Molecular Function | extracellular ligand-gated monoatomic ion channel activity | 4537 / 5,156 | 88.0% | 94.9% of 4,779 | ≥80% support |
| GO | GO:0005254 Molecular Function | chloride channel activity | 3382 / 5,156 | 65.6% | 70.8% of 4,779 | ≥50% support |
| GO | GO:1902476 Biological Process | chloride transmembrane transport | 3382 / 5,156 | 65.6% | 70.8% of 4,779 | ≥50% support |
| GO | GO:1904315 Molecular Function | transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential | 3377 / 5,156 | 65.5% | 70.7% of 4,779 | ≥50% support |
| GO | GO:0005231 Molecular Function | excitatory extracellular ligand-gated monoatomic ion channel activity | 3377 / 5,156 | 65.5% | 70.7% of 4,779 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene00554.t1 | XP_020898489.1 | glycine receptor subunit alpha-2 [Exaiptasia diaphana] | O75311 Glycine receptor subunit alpha-3 OS=Homo sapiens OX=9606 GN= | JBrowse |
| Actinoscyphia liui | gene02751.t1 | XP_020914314.1 | gamma-aminobutyric acid receptor subunit beta-3 [Exaiptasia diaphana] | P63080 Gamma-aminobutyric acid receptor subunit beta-3 OS=Mus muscu | JBrowse |
| Actinoscyphia liui | gene05530.t1 | XP_020902032.1 | glycine receptor subunit alphaZ1 [Exaiptasia diaphana] | P57695 Glycine receptor subunit alpha-1 OS=Bos taurus OX=9913 GN=GL | JBrowse |
| Actinoscyphia liui | gene05531.t1 | XP_020902034.1 | glycine receptor subunit alphaZ1 [Exaiptasia diaphana] | Q91XP5 Glycine receptor subunit alpha-3 OS=Mus musculus OX=10090 GN | JBrowse |
| Actinoscyphia liui | gene05531.t2 | XP_020902034.1 | glycine receptor subunit alphaZ1 [Exaiptasia diaphana] | Q91XP5 Glycine receptor subunit alpha-3 OS=Mus musculus OX=10090 GN | JBrowse |
| Actinoscyphia liui | gene05863.t1 | XP_020903514.1 | glycine receptor subunit alpha-2 isoform X2 [Exaiptasia diaphana] | P18508 Gamma-aminobutyric acid receptor subunit gamma-2 OS=Rattus n | JBrowse |
| Actinoscyphia liui | gene10251.t1 | XP_020899024.1 | gamma-aminobutyric acid receptor alpha-like [Exaiptasia diaphana] | P24046 Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapie | JBrowse |
| Actinoscyphia liui | gene11614.t1 | XP_020892843.1 | gamma-aminobutyric acid receptor subunit gamma-1 [Exaiptasia diaphana] | P28472 Gamma-aminobutyric acid receptor subunit beta-3 OS=Homo sapi | JBrowse |
| Actinoscyphia liui | gene12117.t1 | XP_020913588.1 | gamma-aminobutyric acid receptor subunit beta-2 [Exaiptasia diaphana] | Q91XP5 Glycine receptor subunit alpha-3 OS=Mus musculus OX=10090 GN | JBrowse |
| Actinoscyphia liui | gene12890.t1 | XP_020905154.1 | gamma-aminobutyric acid receptor subunit beta-2-like [Exaiptasia diaphana] | P0C2W5 Gamma-aminobutyric acid receptor subunit beta-2 (Fragment) O | JBrowse |
| Actinoscyphia liui | gene13859.t1 | XP_020912567.1 | glycine receptor subunit alpha-2 [Exaiptasia diaphana] | P0C2W5 Gamma-aminobutyric acid receptor subunit beta-2 (Fragment) O | JBrowse |
| Actinoscyphia liui | gene13859.t2 | XP_020915500.1 | glycine receptor subunit alphaZ1 [Exaiptasia diaphana] | P0C2W5 Gamma-aminobutyric acid receptor subunit beta-2 (Fragment) O | JBrowse |
| Actinoscyphia liui | gene14797.t1 | XP_020906623.1 | glycine receptor subunit alphaZ1 isoform X1 [Exaiptasia diaphana] | F1R8P4 Glycine receptor subunit alpha-2 OS=Danio rerio OX=7955 GN=g | JBrowse |
| Actinoscyphia liui | gene15919.t1 | XP_031559190.1 | glycine receptor subunit alpha-2-like isoform X4 [Actinia tenebrosa] | F1R8P4 Glycine receptor subunit alpha-2 OS=Danio rerio OX=7955 GN=g | JBrowse |
| Actinoscyphia liui | gene15919.t2 | XP_031559190.1 | glycine receptor subunit alpha-2-like isoform X4 [Actinia tenebrosa] | F1R8P4 Glycine receptor subunit alpha-2 OS=Danio rerio OX=7955 GN=g | JBrowse |
| Actinoscyphia liui | gene18713.t1 | XP_020898154.1 | gamma-aminobutyric acid receptor alpha-like [Exaiptasia diaphana] | Q08832 Gamma-aminobutyric acid receptor subunit beta-like OS=Drosop | JBrowse |
| Actinoscyphia liui | gene18714.t1 | XP_020898207.1 | gamma-aminobutyric acid receptor subunit beta-3 [Exaiptasia diaphana] | P24046 Gamma-aminobutyric acid receptor subunit rho-1 OS=Homo sapie | JBrowse |
| Actinoscyphia liui | gene18952.t1 | XP_031573468.1 | gamma-aminobutyric acid receptor subunit beta-4-like [Actinia tenebrosa] | P25123 Gamma-aminobutyric acid receptor subunit beta OS=Drosophila | JBrowse |
| Actinoscyphia liui | gene18952.t2 | CAH3187722.1 | unnamed protein product, partial [Porites evermanni] | P25123 Gamma-aminobutyric acid receptor subunit beta OS=Drosophila | JBrowse |
| Actinoscyphia liui | gene18952.t3 | XP_028515356.1 | gamma-aminobutyric acid receptor subunit alpha-6 isoform X2 [Exaiptasia diaphana] | Q75NA5 Gamma-aminobutyric acid receptor subunit beta OS=Musca domes | JBrowse |
