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This orthogroup contains 3,972 genes from 149 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 3,972 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11733 | ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED | 3597 / 3,972 | 90.6% | 99.8% of 3,605 | ≥80% support |
| Pfam | PF05649 | Peptidase_M13_N — Peptidase family M13 | 3359 / 3,972 | 84.6% | 91.9% of 3,656 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 3664 / 3,972 | 92.3% | 100.0% of 3,666 | ≥80% support |
| GO | GO:0004222 Molecular Function | metalloendopeptidase activity | 3627 / 3,972 | 91.3% | 98.9% of 3,666 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 3598 / 3,972 | 90.6% | 98.2% of 3,666 | ≥80% support |
| GO | GO:0016485 Biological Process | protein processing | 3574 / 3,972 | 90.0% | 97.5% of 3,666 | ≥80% support |
| GO | GO:0008237 Molecular Function | metallopeptidase activity | 3515 / 3,972 | 88.5% | 95.9% of 3,666 | ≥80% support |
| Pfam | PF01431 | Peptidase_M13 — Peptidase family M13 | 3117 / 3,972 | 78.5% | 85.3% of 3,656 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene04707.t1 | XP_031559890.1 | endothelin-converting enzyme 1-like [Actinia tenebrosa] | B2RQR8 Endothelin-converting enzyme 2 OS=Mus musculus OX=10090 GN=E | JBrowse |
| Actinoscyphia liui | gene05750.t1 | XP_031573865.1 | endothelin-converting enzyme 1-like [Actinia tenebrosa] | P0DPD6 Endothelin-converting enzyme 2 OS=Homo sapiens OX=9606 GN=EC | JBrowse |
| Actinoscyphia liui | gene06025.t1 | XP_020904176.1 | neprilysin-4 [Exaiptasia diaphana] | Q4PZA2 Endothelin-converting enzyme 1 OS=Mus musculus OX=10090 GN=E | JBrowse |
| Actinoscyphia liui | gene10755.t1 | XP_020899185.1 | endothelin-converting enzyme 1 [Exaiptasia diaphana] | P42891 Endothelin-converting enzyme 1 OS=Bos taurus OX=9913 GN=ECE1 | JBrowse |
| Actinoscyphia liui | gene10833.t1 | XP_028514498.1 | endothelin-converting enzyme 2 [Exaiptasia diaphana] | Q9JLI3 Membrane metallo-endopeptidase-like 1 OS=Mus musculus OX=100 | JBrowse |
| Actinoscyphia liui | gene16674.t1 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Actinoscyphia liui | gene16675.t1 | KXJ27346.1 | Endothelin-converting enzyme 1 [Exaiptasia diaphana] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Actinoscyphia liui | gene16680.t1 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Actinoscyphia liui | gene16682.t1 | XP_020915472.1 | neprilysin-4, partial [Exaiptasia diaphana] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Actinoscyphia liui | gene16734.t1 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Actinoscyphia liui | gene16735.t1 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Actinoscyphia liui | gene16736.t1 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | P97739 Endothelin-converting enzyme 1 OS=Cavia porcellus OX=10141 G | JBrowse |
| Actinoscyphia liui | gene16736.t2 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | P97739 Endothelin-converting enzyme 1 OS=Cavia porcellus OX=10141 G | JBrowse |
| Actinoscyphia liui | gene16737.t1 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Actinoscyphia liui | gene16742.t1 | XP_028514139.1 | neprilysin-4 [Exaiptasia diaphana] | F1N476 Endothelin-converting enzyme 2 OS=Bos taurus OX=9913 GN=ECE2 | JBrowse |
| Actinoscyphia liui | gene16744.t1 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | Q8IS64 Endothelin-converting enzyme homolog OS=Locusta migratoria O | JBrowse |
| Actinoscyphia liui | gene16745.t2 | XP_020901218.1 | neprilysin [Exaiptasia diaphana] | P42893 Endothelin-converting enzyme 1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Actinoscyphia liui | gene16872.t1 | XP_020904942.1 | endothelin-converting enzyme homolog [Exaiptasia diaphana] | Q9W5Y0 Neprilysin-3 OS=Drosophila melanogaster OX=7227 GN=Nep3 PE=2 | JBrowse |
| Actinoscyphia liui | gene26480.t1 | KXJ12756.1 | Endothelin-converting enzyme 1 [Exaiptasia diaphana] | P42891 Endothelin-converting enzyme 1 OS=Bos taurus OX=9913 GN=ECE1 | JBrowse |
| Actinoscyphia liui | gene26480.t2 | KXJ12756.1 | Endothelin-converting enzyme 1 [Exaiptasia diaphana] | – | JBrowse |
