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This orthogroup contains 3,362 genes from 149 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 3,362 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR42884 | PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED | 2930 / 3,362 | 87.2% | 97.9% of 2,992 | ≥80% support |
| GO | GO:0004252 Molecular Function | serine-type endopeptidase activity | 2965 / 3,362 | 88.2% | 99.6% of 2,976 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 2947 / 3,362 | 87.7% | 99.0% of 2,976 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 2931 / 3,362 | 87.2% | 98.5% of 2,976 | ≥80% support |
| GO | GO:0016485 Biological Process | protein processing | 2930 / 3,362 | 87.2% | 98.5% of 2,976 | ≥80% support |
| GO | GO:0005802 Cellular Component | trans-Golgi network | 2691 / 3,362 | 80.0% | 90.4% of 2,976 | ≥80% support |
| GO | GO:0030173 Cellular Component | obsolete integral component of Golgi membrane | 2691 / 3,362 | 80.0% | 90.4% of 2,976 | ≥80% support |
| Pfam | PF00082 | Peptidase_S8 — Subtilase family | 2686 / 3,362 | 79.9% | 90.5% of 2,969 | ≥50% support |
| Pfam | PF01483 | P_proprotein — Proprotein convertase P-domain | 2441 / 3,362 | 72.6% | 82.2% of 2,969 | ≥50% support |
| Pfam | PF16470 | S8_pro-domain — Peptidase S8 pro-domain | 1759 / 3,362 | 52.3% | 59.3% of 2,969 | ≥50% support |
| GO | GO:0008236 Molecular Function | serine-type peptidase activity | 2686 / 3,362 | 79.9% | 90.3% of 2,976 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene00498.t1 | XP_020914316.1 | neuroendocrine convertase 1 [Exaiptasia diaphana] | P28840 Neuroendocrine convertase 1 OS=Rattus norvegicus OX=10116 GN | JBrowse |
| Actinoscyphia liui | gene01705.t1 | XP_020903110.1 | neuroendocrine convertase 2 isoform X2 [Exaiptasia diaphana] | P29122 Proprotein convertase subtilisin/kexin type 6 OS=Homo sapien | JBrowse |
| Actinoscyphia liui | gene01706.t1 | KXJ12796.1 | Proprotein convertase subtilisin/kexin type 6 [Exaiptasia diaphana] | Q63415 Proprotein convertase subtilisin/kexin type 6 OS=Rattus norv | JBrowse |
| Actinoscyphia liui | gene02912.t1 | XP_028519343.1 | proprotein convertase subtilisin/kexin type 6 isoform X2 [Exaiptasia diaphana] | Q63415 Proprotein convertase subtilisin/kexin type 6 OS=Rattus norv | JBrowse |
| Actinoscyphia liui | gene05738.t1 | XP_031550934.1 | PC3-like endoprotease variant B [Actinia tenebrosa] | P29145 PC3-like endoprotease variant B OS=Hydra vulgaris OX=6087 PE | JBrowse |
| Actinoscyphia liui | gene10426.t1 | XP_020899158.1 | proprotein convertase subtilisin/kexin type 7 isoform X1 [Exaiptasia diaphana] | Q61139 Proprotein convertase subtilisin/kexin type 7 OS=Mus musculu | JBrowse |
| Actinoscyphia liui | gene27433.t1 | XP_020900946.1 | neuroendocrine convertase 2 [Exaiptasia diaphana] | P29120 Neuroendocrine convertase 1 OS=Homo sapiens OX=9606 GN=PCSK1 | JBrowse |
| Actinoscyphia liui | gene27433.t2 | XP_020900946.1 | neuroendocrine convertase 2 [Exaiptasia diaphana] | P29145 PC3-like endoprotease variant B OS=Hydra vulgaris OX=6087 PE | JBrowse |
| Actinoscyphia liui | gene29464.t1 | XP_020910329.1 | PC3-like endoprotease variant B [Exaiptasia diaphana] | P29146 PC3-like endoprotease variant A OS=Hydra vulgaris OX=6087 PE | JBrowse |
| Actinoscyphia liui | gene29465.t1 | XP_020910353.2 | PC3-like endoprotease variant B [Exaiptasia diaphana] | P29145 PC3-like endoprotease variant B OS=Hydra vulgaris OX=6087 PE | JBrowse |
| Actinoscyphia liui | gene29465.t2 | XP_020910353.2 | PC3-like endoprotease variant B [Exaiptasia diaphana] | P29145 PC3-like endoprotease variant B OS=Hydra vulgaris OX=6087 PE | JBrowse |
| Actinoscyphia liui | gene29467.t1 | KXJ24439.1 | PC3-like endoprotease variant A [Exaiptasia diaphana] | P29146 PC3-like endoprotease variant A OS=Hydra vulgaris OX=6087 PE | JBrowse |
| Actinoscyphia liui | gene29467.t2 | XP_020910353.2 | PC3-like endoprotease variant B [Exaiptasia diaphana] | P29146 PC3-like endoprotease variant A OS=Hydra vulgaris OX=6087 PE | JBrowse |
| Actinoscyphia liui | gene29468.t1 | XP_028517707.1 | uncharacterized protein LOC110248172 [Exaiptasia diaphana] | P29145 PC3-like endoprotease variant B OS=Hydra vulgaris OX=6087 PE | JBrowse |
| Actinoscyphia liui | gene29474.t1 | XP_031553660.1 | furin-like protease 1, isoforms 1/1-X/2 [Actinia tenebrosa] | P29145 PC3-like endoprotease variant B OS=Hydra vulgaris OX=6087 PE | JBrowse |
