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This orthogroup contains 3,218 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 3,218 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11920 | GUANYLYL CYCLASE | 2438 / 3,218 | 75.8% | 85.7% of 2,846 | ≥50% support |
| Pfam | PF00211 | Guanylate_cyc — Adenylate and Guanylate cyclase catalytic domain | 2256 / 3,218 | 70.1% | 78.1% of 2,888 | ≥50% support |
| Pfam | PF01094 | ANF_receptor — Receptor family ligand binding region | 2207 / 3,218 | 68.6% | 76.4% of 2,888 | ≥50% support |
| Pfam | PF07714 | PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase | 2123 / 3,218 | 66.0% | 73.5% of 2,888 | ≥50% support |
| GO | GO:0004383 Molecular Function | guanylate cyclase activity | 2439 / 3,218 | 75.8% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 2439 / 3,218 | 75.8% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0001653 Molecular Function | peptide receptor activity | 2437 / 3,218 | 75.7% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0004016 Molecular Function | adenylate cyclase activity | 2437 / 3,218 | 75.7% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0006182 Biological Process | cGMP biosynthetic process | 2437 / 3,218 | 75.7% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0007168 Biological Process | receptor guanylyl cyclase signaling pathway | 2437 / 3,218 | 75.7% | 85.9% of 2,838 | ≥50% support |
| GO | GO:0009190 Biological Process | cyclic nucleotide biosynthetic process | 2259 / 3,218 | 70.2% | 79.6% of 2,838 | ≥50% support |
| GO | GO:0035556 Biological Process | intracellular signal transduction | 2259 / 3,218 | 70.2% | 79.6% of 2,838 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 2162 / 3,218 | 67.2% | 76.2% of 2,838 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 2162 / 3,218 | 67.2% | 76.2% of 2,838 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 2127 / 3,218 | 66.1% | 75.0% of 2,838 | ≥50% support |
| GO | GO:0016849 Molecular Function | phosphorus-oxygen lyase activity | 1828 / 3,218 | 56.8% | 64.4% of 2,838 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene03436.t1 | EDO36182.1 | predicted protein [Nematostella vectensis] | P16065 Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE | JBrowse |
| Actinoscyphia liui | gene03437.t1 | XP_031570824.1 | LOW QUALITY PROTEIN: speract receptor-like [Actinia tenebrosa] | P18910 Atrial natriuretic peptide receptor 1 OS=Rattus norvegicus O | JBrowse |
| Actinoscyphia liui | gene03935.t1 | XP_028516034.1 | LOW QUALITY PROTEIN: atrial natriuretic peptide receptor 1-like [Exaiptasia diaphana] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Actinoscyphia liui | gene08847.t1 | XP_020901343.1 | atrial natriuretic peptide receptor 1 isoform X2 [Exaiptasia diaphana] | Q07553 Guanylate cyclase 32E OS=Drosophila melanogaster OX=7227 GN= | JBrowse |
| Actinoscyphia liui | gene08919.t1 | XP_020901343.1 | atrial natriuretic peptide receptor 1 isoform X2 [Exaiptasia diaphana] | Q07553 Guanylate cyclase 32E OS=Drosophila melanogaster OX=7227 GN= | JBrowse |
| Actinoscyphia liui | gene10545.t1 | KXJ12157.1 | Atrial natriuretic peptide receptor 1 [Exaiptasia diaphana] | – | JBrowse |
| Actinoscyphia liui | gene10545.t2 | XP_031556270.1 | atrial natriuretic peptide receptor 1-like [Actinia tenebrosa] | H2L002 Receptor-type guanylate cyclase gcy-7 OS=Caenorhabditis eleg | JBrowse |
| Actinoscyphia liui | gene10545.t3 | XP_031556270.1 | atrial natriuretic peptide receptor 1-like [Actinia tenebrosa] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Actinoscyphia liui | gene10545.t4 | XP_031556270.1 | atrial natriuretic peptide receptor 1-like [Actinia tenebrosa] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Actinoscyphia liui | gene10546.t1 | XP_020904271.1 | atrial natriuretic peptide receptor 2 [Exaiptasia diaphana] | Q07553 Guanylate cyclase 32E OS=Drosophila melanogaster OX=7227 GN= | JBrowse |
| Actinoscyphia liui | gene10657.t1 | XP_020901339.1 | atrial natriuretic peptide receptor 1 isoform X1 [Exaiptasia diaphana] | P16065 Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE | JBrowse |
| Actinoscyphia liui | gene10657.t2 | XP_020901343.1 | atrial natriuretic peptide receptor 1 isoform X2 [Exaiptasia diaphana] | P16065 Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE | JBrowse |
| Actinoscyphia liui | gene10658.t1 | XP_031575272.1 | speract receptor-like isoform X1 [Actinia tenebrosa] | P16065 Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE | JBrowse |
| Actinoscyphia liui | gene10701.t1 | XP_031573570.1 | speract receptor-like [Actinia tenebrosa] | P18293 Atrial natriuretic peptide receptor 1 OS=Mus musculus OX=100 | JBrowse |
| Actinoscyphia liui | gene11410.t1 | XP_020906809.2 | LOW QUALITY PROTEIN: speract receptor-like [Exaiptasia diaphana] | P18910 Atrial natriuretic peptide receptor 1 OS=Rattus norvegicus O | JBrowse |
| Actinoscyphia liui | gene11756.t1 | XP_031556495.1 | atrial natriuretic peptide receptor 1-like [Actinia tenebrosa] | Q07553 Guanylate cyclase 32E OS=Drosophila melanogaster OX=7227 GN= | JBrowse |
| Actinoscyphia liui | gene12062.t1 | XP_031570423.1 | atrial natriuretic peptide receptor 1-like [Actinia tenebrosa] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Actinoscyphia liui | gene21431.t1 | XP_031572375.1 | atrial natriuretic peptide receptor 1-like [Actinia tenebrosa] | P16066 Atrial natriuretic peptide receptor 1 OS=Homo sapiens OX=960 | JBrowse |
| Actinoscyphia liui | gene21434.t1 | XP_031572375.1 | atrial natriuretic peptide receptor 1-like [Actinia tenebrosa] | – | JBrowse |
| Actinoscyphia liui | gene21506.t1 | XP_031570053.1 | atrial natriuretic peptide receptor 1-like [Actinia tenebrosa] | P16065 Speract receptor OS=Strongylocentrotus purpuratus OX=7668 PE | JBrowse |
