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This orthogroup contains 1,515 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,515 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11256 | BCL-2 RELATED | 1339 / 1,515 | 88.4% | 99.8% of 1,342 | ≥80% support |
| Pfam | PF00452 | Bcl-2 | 1343 / 1,515 | 88.7% | 99.9% of 1,344 | ≥80% support |
| GO | GO:0042981 Biological Process | regulation of apoptotic process | 1350 / 1,515 | 89.1% | 99.9% of 1,351 | ≥80% support |
| GO | GO:0005741 Cellular Component | mitochondrial outer membrane | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
| GO | GO:0008630 Biological Process | intrinsic apoptotic signaling pathway in response to DNA damage | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
| GO | GO:0042803 Molecular Function | protein homodimerization activity | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
| GO | GO:0046982 Molecular Function | protein heterodimerization activity | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
| GO | GO:0097192 Biological Process | extrinsic apoptotic signaling pathway in absence of ligand | 1339 / 1,515 | 88.4% | 99.1% of 1,351 | ≥80% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene00557.t1 | XP_020898459.1 | induced myeloid leukemia cell differentiation protein Mcl-1 homolog [Exaiptasia diaphana] | – | JBrowse |
| Actinoscyphia liui | gene02963.t1 | XP_020904756.1 | bcl-2-like protein 1 [Exaiptasia diaphana] | Q64373 Bcl-2-like protein 1 OS=Mus musculus OX=10090 GN=Bcl2l1 PE=1 | JBrowse |
| Actinoscyphia liui | gene02963.t2 | XP_020904756.1 | bcl-2-like protein 1 [Exaiptasia diaphana] | Q64373 Bcl-2-like protein 1 OS=Mus musculus OX=10090 GN=Bcl2l1 PE=1 | JBrowse |
| Actinoscyphia liui | gene02996.t1 | XP_020904924.1 | bcl-2-like protein 2 isoform X2 [Exaiptasia diaphana] | Q07817 Bcl-2-like protein 1 OS=Homo sapiens OX=9606 GN=BCL2L1 PE=1 | JBrowse |
| Actinoscyphia liui | gene03354.t1 | XP_020904837.1 | bcl-2-like protein 1 [Exaiptasia diaphana] | Q3C2I0 Bcl-2-related protein A1 OS=Bos taurus OX=9913 GN=BCL2A1 PE= | JBrowse |
| Actinoscyphia liui | gene08719.t1 | KXJ10701.1 | Apoptosis regulator BAX [Exaiptasia diaphana] | Q07813 Apoptosis regulator BAX OS=Mus musculus OX=10090 GN=Bax PE=1 | JBrowse |
| Actinoscyphia liui | gene24636.t1 | XP_020892397.1 | apoptosis regulator Bcl-2 [Exaiptasia diaphana] | Q07817 Bcl-2-like protein 1 OS=Homo sapiens OX=9606 GN=BCL2L1 PE=1 | JBrowse |
| Actinoscyphia liui | gene28113.t1 | XP_020902779.1 | bcl-2 homologous antagonist/killer [Exaiptasia diaphana] | Q16611 Bcl-2 homologous antagonist/killer OS=Homo sapiens OX=9606 G | JBrowse |
| Actinoscyphia liui | gene28113.t2 | XP_020902779.1 | bcl-2 homologous antagonist/killer [Exaiptasia diaphana] | Q16611 Bcl-2 homologous antagonist/killer OS=Homo sapiens OX=9606 G | JBrowse |
| Actinoscyphia liui | gene28204.t1 | XP_020912229.1 | apoptosis regulator R1 [Exaiptasia diaphana] | P70345 Bcl-2-like protein 2 OS=Mus musculus OX=10090 GN=Bcl2l2 PE=1 | JBrowse |
