Gene Family

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Member genes
1,293
Species
144
Sequences
1,293
Best annotation support
89.3%

Consensus functional annotation

No term is shared by every member gene — the best-supported term below covers 89.3% of the 1,293 members.

Support counts the member genes carrying the term. % of genes is that count over all 1,293 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PANTHERPTHR10985BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED1155 / 1,29389.3%99.9%
of 1,156
≥80% support
PfamPF00010HLH — Helix-loop-helix DNA-binding domain1131 / 1,29387.5%97.1%
of 1,165
≥80% support
GOGO:0005634
Cellular Component
nucleus1156 / 1,29389.4%98.1%
of 1,179
≥80% support
GOGO:0000978
Molecular Function
RNA polymerase II cis-regulatory region sequence-specific DNA binding1155 / 1,29389.3%98.0%
of 1,179
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific1155 / 1,29389.3%98.0%
of 1,179
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II1155 / 1,29389.3%98.0%
of 1,179
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity1154 / 1,29389.3%97.9%
of 1,179
≥80% support
GOGO:0009952
Biological Process
anterior/posterior pattern specification1150 / 1,29388.9%97.5%
of 1,179
≥80% support
GOGO:0050767
Biological Process
regulation of neurogenesis1150 / 1,29388.9%97.5%
of 1,179
≥80% support
PfamPF07527Hairy_orange — Hairy Orange678 / 1,29352.4%58.2%
of 1,165
≥50% support
GOGO:0003677
Molecular Function
DNA binding716 / 1,29355.4%60.7%
of 1,179
≥50% support
GOGO:0006355
Biological Process
regulation of DNA-templated transcription715 / 1,29355.3%60.6%
of 1,179
≥50% support
KEGGK06054HES1 — DNA repair and recombination proteins756 / 1,29358.5%97.2%
of 778
≥50% support
📊 Total members in OG0000541: 12 (filtered to ALIUI · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Actinoscyphia liuigene21306.t1RMX40216.1hypothetical protein pdam_00016547 [Pocillopora damicornis]Q90Z12
Transcription factor HES-4-A OS=Xenopus laevis OX=8355 GN=he
JBrowse
Actinoscyphia liuigene21423.t1KXJ10594.1Transcription factor HES-1-A [Exaiptasia diaphana]Q9HCC6
Transcription factor HES-4 OS=Homo sapiens OX=9606 GN=HES4 P
JBrowse
Actinoscyphia liuigene24834.t1XP_020906375.1enhancer of split m8 protein [Exaiptasia diaphana]Q01071
Enhancer of split mdelta protein OS=Drosophila melanogaster
JBrowse
Actinoscyphia liuigene24838.t1XP_020906554.1hairy/enhancer-of-split related with YRPW motif protein 1-like [Exaiptasia diaphana]Q00P32
Transcription factor HES-2 OS=Xenopus laevis OX=8355 GN=hes2
JBrowse
Actinoscyphia liuigene24838.t2XP_020906554.1hairy/enhancer-of-split related with YRPW motif protein 1-like [Exaiptasia diaphana]Q9Y543
Transcription factor HES-2 OS=Homo sapiens OX=9606 GN=HES2 P
JBrowse
Actinoscyphia liuigene24839.t1KXJ20177.1Enhancer of split mdelta protein [Exaiptasia diaphana]Q90VV1
Transcription factor HES-4-B OS=Xenopus laevis OX=8355 GN=he
JBrowse
Actinoscyphia liuigene25269.t1XP_020906317.1transcription factor HES-1 [Exaiptasia diaphana]JBrowse
Actinoscyphia liuigene25269.t2XP_020906317.1transcription factor HES-1 [Exaiptasia diaphana]Q90VV1
Transcription factor HES-4-B OS=Xenopus laevis OX=8355 GN=he
JBrowse
Actinoscyphia liuigene25270.t1XP_020906314.1transcription factor HES-2 [Exaiptasia diaphana]Q90VV1
Transcription factor HES-4-B OS=Xenopus laevis OX=8355 GN=he
JBrowse
Actinoscyphia liuigene25272.t1XP_020906316.1transcription factor HES-1 [Exaiptasia diaphana]Q8AVU4
Transcription factor HES-1-B OS=Xenopus laevis OX=8355 GN=he
JBrowse
Actinoscyphia liuigene25273.t1XP_020906311.2uncharacterized protein LOC110244444 [Exaiptasia diaphana]Q00P32
Transcription factor HES-2 OS=Xenopus laevis OX=8355 GN=hes2
JBrowse
Actinoscyphia liuigene25274.t1XP_020906300.1transcription factor HES-2 [Exaiptasia diaphana]P35429
Transcription factor HES-2 OS=Rattus norvegicus OX=10116 GN=
JBrowse
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