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This orthogroup contains 1,236 genes from 148 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 1,236 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10869 | PROLYL 4-HYDROXYLASE ALPHA SUBUNIT | 992 / 1,236 | 80.3% | 99.2% of 1,000 | ≥80% support |
| GO | GO:0004656 Molecular Function | procollagen-proline 4-dioxygenase activity | 1089 / 1,236 | 88.1% | 98.6% of 1,104 | ≥80% support |
| GO | GO:0005783 Cellular Component | endoplasmic reticulum | 1089 / 1,236 | 88.1% | 98.6% of 1,104 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 1000 / 1,236 | 80.9% | 90.6% of 1,104 | ≥80% support |
| GO | GO:0018401 Biological Process | peptidyl-proline hydroxylation to 4-hydroxy-L-proline | 992 / 1,236 | 80.3% | 89.9% of 1,104 | ≥80% support |
| Pfam | PF08336 | P4Ha_N — Prolyl 4-Hydroxylase alpha-subunit, N-terminal region | 955 / 1,236 | 77.3% | 89.3% of 1,069 | ≥50% support |
| Pfam | PF13640 | 2OG-FeII_Oxy_3 — 2OG-Fe(II) oxygenase superfamily | 888 / 1,236 | 71.8% | 83.1% of 1,069 | ≥50% support |
| GO | GO:0005506 Molecular Function | iron ion binding | 953 / 1,236 | 77.1% | 86.3% of 1,104 | ≥50% support |
| GO | GO:0016705 Molecular Function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 952 / 1,236 | 77.0% | 86.2% of 1,104 | ≥50% support |
| GO | GO:0031418 Molecular Function | L-ascorbic acid binding | 952 / 1,236 | 77.0% | 86.2% of 1,104 | ≥50% support |
| KEGG | K00472 | P4HA — Arginine and proline metabolism | 899 / 1,236 | 72.7% | 99.0% of 908 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene11299.t1 | XP_020898708.1 | prolyl 4-hydroxylase subunit alpha-2 [Exaiptasia diaphana] | Q60715 Prolyl 4-hydroxylase subunit alpha-1 OS=Mus musculus OX=1009 | JBrowse |
| Actinoscyphia liui | gene24429.t1 | XP_020896561.1 | prolyl 4-hydroxylase subunit alpha-2 [Exaiptasia diaphana] | O15460 Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 | JBrowse |
| Actinoscyphia liui | gene24430.t1 | XP_031563909.1 | prolyl 4-hydroxylase subunit alpha-1-like isoform X1 [Actinia tenebrosa] | Q1RMU3 Prolyl 4-hydroxylase subunit alpha-1 OS=Bos taurus OX=9913 G | JBrowse |
| Actinoscyphia liui | gene24431.t1 | XP_020896563.1 | prolyl 4-hydroxylase subunit alpha-1 [Exaiptasia diaphana] | P13674 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 | JBrowse |
| Actinoscyphia liui | gene27372.t1 | XP_020914563.1 | prolyl 4-hydroxylase subunit alpha-1 [Exaiptasia diaphana] | Q10576 Prolyl 4-hydroxylase subunit alpha-1 OS=Caenorhabditis elega | JBrowse |
| Actinoscyphia liui | gene27373.t1 | XP_020914549.1 | prolyl 4-hydroxylase subunit alpha-1 [Exaiptasia diaphana] | P13674 Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 | JBrowse |
