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This orthogroup contains 864 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 864 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10183 | CALPAIN | 729 / 864 | 84.4% | 95.5% of 763 | ≥80% support |
| GO | GO:0004198 Molecular Function | calcium-dependent cysteine-type endopeptidase activity | 729 / 864 | 84.4% | 96.3% of 757 | ≥80% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 729 / 864 | 84.4% | 96.3% of 757 | ≥80% support |
| GO | GO:0006508 Biological Process | proteolysis | 729 / 864 | 84.4% | 96.3% of 757 | ≥80% support |
| Pfam | PF01067 | Calpain_III — Calpain large subunit, domain III | 685 / 864 | 79.3% | 90.4% of 758 | ≥50% support |
| Pfam | PF00648 | Peptidase_C2 — Calpain family cysteine protease | 677 / 864 | 78.4% | 89.3% of 758 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene16404.t1 | XP_020903755.1 | calpain-5 [Exaiptasia diaphana] | O08688 Calpain-5 OS=Mus musculus OX=10090 GN=Capn5 PE=1 SV=1 | JBrowse |
| Actinoscyphia liui | gene16405.t1 | XP_020903755.1 | calpain-5 [Exaiptasia diaphana] | O15484 Calpain-5 OS=Homo sapiens OX=9606 GN=CAPN5 PE=1 SV=2 | JBrowse |
| Actinoscyphia liui | gene19480.t1 | XP_020907154.2 | LOW QUALITY PROTEIN: calpain-A-like [Exaiptasia diaphana] | Q9VT65 Calpain-B OS=Drosophila melanogaster OX=7227 GN=CalpB PE=1 S | JBrowse |
| Actinoscyphia liui | gene20392.t1 | XP_020896918.1 | calpain-B isoform X1 [Exaiptasia diaphana] | Q9VT65 Calpain-B OS=Drosophila melanogaster OX=7227 GN=CalpB PE=1 S | JBrowse |
| Actinoscyphia liui | gene20393.t1 | XP_020896809.1 | calpain-B isoform X2 [Exaiptasia diaphana] | Q11002 Calpain-A OS=Drosophila melanogaster OX=7227 GN=CalpA PE=1 S | JBrowse |
| Actinoscyphia liui | gene20394.t1 | XP_020896809.1 | calpain-B isoform X2 [Exaiptasia diaphana] | Q9VT65 Calpain-B OS=Drosophila melanogaster OX=7227 GN=CalpB PE=1 S | JBrowse |
