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This orthogroup contains 853 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 853 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF02221 | E1_DerP2_DerF2 — ML domain | 765 / 853 | 89.7% | 100.0% of 765 | ≥80% support |
| PANTHER | PTHR11306 | NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED | 675 / 853 | 79.1% | 99.7% of 677 | ≥50% support |
| GO | GO:0015918 Biological Process | sterol transport | 675 / 853 | 79.1% | 99.7% of 677 | ≥50% support |
| GO | GO:0032934 Molecular Function | sterol binding | 675 / 853 | 79.1% | 99.7% of 677 | ≥50% support |
| KEGG | K13443 | NPC2 — Transporters | 526 / 853 | 61.7% | 99.8% of 527 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene16647.t1 | XP_020902369.1 | NPC intracellular cholesterol transporter 2 [Exaiptasia diaphana] | Q9Z0J0 NPC intracellular cholesterol transporter 2 OS=Mus musculus | JBrowse |
| Actinoscyphia liui | gene16648.t1 | XP_020902369.1 | NPC intracellular cholesterol transporter 2 [Exaiptasia diaphana] | Q9Z0J0 NPC intracellular cholesterol transporter 2 OS=Mus musculus | JBrowse |
| Actinoscyphia liui | gene16649.t1 | XP_020902369.1 | NPC intracellular cholesterol transporter 2 [Exaiptasia diaphana] | Q9Z0J0 NPC intracellular cholesterol transporter 2 OS=Mus musculus | JBrowse |
| Actinoscyphia liui | gene19693.t1 | XP_020896830.1 | NPC intracellular cholesterol transporter 2 [Exaiptasia diaphana] | P61916 NPC intracellular cholesterol transporter 2 OS=Homo sapiens | JBrowse |
| Actinoscyphia liui | gene19694.t1 | XP_031558579.1 | NPC intracellular cholesterol transporter 2-like [Actinia tenebrosa] | Q9VQ62 NPC intracellular cholesterol transporter 2 homolog a OS=Dro | JBrowse |
| Actinoscyphia liui | gene19695.t1 | XP_020896833.1 | NPC intracellular cholesterol transporter 2 homolog a-like [Exaiptasia diaphana] | Q9VQ62 NPC intracellular cholesterol transporter 2 homolog a OS=Dro | JBrowse |
