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This orthogroup contains 791 genes from 144 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 791 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24372 | GLYCOPROTEIN HORMONE RECEPTOR | 661 / 791 | 83.6% | 94.4% of 700 | ≥80% support |
| Pfam | PF00001 | 7tm_1 — 7 transmembrane receptor (rhodopsin family) | 653 / 791 | 82.6% | 93.7% of 697 | ≥80% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 668 / 791 | 84.5% | 95.3% of 701 | ≥80% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 662 / 791 | 83.7% | 94.4% of 701 | ≥80% support |
| GO | GO:0007189 Biological Process | adenylate cyclase-activating G protein-coupled receptor signaling pathway | 661 / 791 | 83.6% | 94.3% of 701 | ≥80% support |
| GO | GO:0007190 Biological Process | activation of adenylate cyclase activity | 661 / 791 | 83.6% | 94.3% of 701 | ≥80% support |
| GO | GO:0008528 Molecular Function | G protein-coupled peptide receptor activity | 661 / 791 | 83.6% | 94.3% of 701 | ≥80% support |
| GO | GO:0009755 Biological Process | hormone-mediated signaling pathway | 661 / 791 | 83.6% | 94.3% of 701 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 660 / 791 | 83.4% | 94.2% of 701 | ≥80% support |
| GO | GO:0007186 Biological Process | G protein-coupled receptor signaling pathway | 657 / 791 | 83.1% | 93.7% of 701 | ≥80% support |
| GO | GO:0016500 Molecular Function | protein-hormone receptor activity | 656 / 791 | 82.9% | 93.6% of 701 | ≥80% support |
| GO | GO:0004930 Molecular Function | G protein-coupled receptor activity | 655 / 791 | 82.8% | 93.4% of 701 | ≥80% support |
| Pfam | PF13855 | LRR_8 — Leucine rich repeat | 560 / 791 | 70.8% | 80.3% of 697 | ≥50% support |
| GO | GO:0005515 Molecular Function | protein binding | 579 / 791 | 73.2% | 82.6% of 701 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene08181.t1 | XP_028513810.1 | leucine-rich repeat-containing G-protein coupled receptor 5 isoform X1 [Exaiptasia diaphana] | Q9BGN4 Thyrotropin receptor OS=Felis catus OX=9685 GN=TSHR PE=2 SV= | JBrowse |
| Actinoscyphia liui | gene11861.t1 | XP_020892857.1 | probable glycoprotein hormone G-protein coupled receptor [Exaiptasia diaphana] | P35409 Probable glycoprotein hormone G-protein coupled receptor OS= | JBrowse |
| Actinoscyphia liui | gene11861.t2 | KXJ18611.1 | putative glycoprotein hormone G-protein coupled receptor [Exaiptasia diaphana] | P35409 Probable glycoprotein hormone G-protein coupled receptor OS= | JBrowse |
| Actinoscyphia liui | gene11862.t1 | XP_031549743.1 | lutropin-choriogonadotropic hormone receptor-like isoform X2 [Actinia tenebrosa] | Q7ZTV5 Follicle-stimulating hormone receptor OS=Cairina moschata OX | JBrowse |
