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This orthogroup contains 583 genes from 147 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 583 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10048 | PHOSPHATIDYLINOSITOL KINASE | 442 / 583 | 75.8% | 98.0% of 451 | ≥50% support |
| Pfam | PF00454 | PI3_PI4_kinase — Phosphatidylinositol 3- and 4-kinase | 421 / 583 | 72.2% | 86.1% of 489 | ≥50% support |
| Pfam | PF00613 | PI3Ka — Phosphoinositide 3-kinase family, accessory domain (PIK domain) | 420 / 583 | 72.0% | 85.9% of 489 | ≥50% support |
| Pfam | PF00792 | PI3K_C2 — Phosphoinositide 3-kinase C2 | 389 / 583 | 66.7% | 79.6% of 489 | ≥50% support |
| Pfam | PF00794 | PI3K_rbd — PI3-kinase family, ras-binding domain | 378 / 583 | 64.8% | 77.3% of 489 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 446 / 583 | 76.5% | 98.7% of 452 | ≥50% support |
| GO | GO:0016020 Cellular Component | membrane | 445 / 583 | 76.3% | 98.5% of 452 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 443 / 583 | 76.0% | 98.0% of 452 | ≥50% support |
| GO | GO:0016303 Molecular Function | 1-phosphatidylinositol-3-kinase activity | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0016477 Biological Process | cell migration | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0035005 Molecular Function | 1-phosphatidylinositol-4-phosphate 3-kinase activity | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0036092 Biological Process | phosphatidylinositol-3-phosphate biosynthetic process | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0046854 Biological Process | phosphatidylinositol phosphate biosynthetic process | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0048015 Biological Process | phosphatidylinositol-mediated signaling | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0052742 Molecular Function | phosphatidylinositol kinase activity | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0014065 Biological Process | obsolete phosphatidylinositol 3-kinase signaling | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0005942 Cellular Component | phosphatidylinositol 3-kinase complex | 442 / 583 | 75.8% | 97.8% of 452 | ≥50% support |
| GO | GO:0016301 Molecular Function | kinase activity | 413 / 583 | 70.8% | 91.4% of 452 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene01789.t1 | XP_020894399.1 | phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [Exaiptasia diaphana] | O00750 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containi | JBrowse |
| Actinoscyphia liui | gene27352.t1 | XP_031554443.1 | phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform-like [Actinia tenebrosa] | Q8BTI9 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic sub | JBrowse |
