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This orthogroup contains 572 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 572 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11827 | SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS | 514 / 572 | 89.9% | 100.0% of 514 | ≥80% support |
| Pfam | PF00324 | AA_permease — Amino acid permease | 479 / 572 | 83.7% | 92.7% of 517 | ≥80% support |
| Pfam | PF03522 | SLC12 — Solute carrier family 12 | 466 / 572 | 81.5% | 90.1% of 517 | ≥80% support |
| GO | GO:0016020 Cellular Component | membrane | 517 / 572 | 90.4% | 100.0% of 517 | ≥80% support |
| GO | GO:0006811 Biological Process | monoatomic ion transport | 517 / 572 | 90.4% | 100.0% of 517 | ≥80% support |
| GO | GO:0055075 Biological Process | potassium ion homeostasis | 514 / 572 | 89.9% | 99.4% of 517 | ≥80% support |
| GO | GO:1990573 Biological Process | potassium ion import across plasma membrane | 514 / 572 | 89.9% | 99.4% of 517 | ≥80% support |
| GO | GO:1902476 Biological Process | chloride transmembrane transport | 514 / 572 | 89.9% | 99.4% of 517 | ≥80% support |
| GO | GO:0055064 Biological Process | chloride ion homeostasis | 514 / 572 | 89.9% | 99.4% of 517 | ≥80% support |
| GO | GO:0015379 Molecular Function | potassium:chloride symporter activity | 514 / 572 | 89.9% | 99.4% of 517 | ≥80% support |
| GO | GO:0015377 Molecular Function | chloride:monoatomic cation symporter activity | 514 / 572 | 89.9% | 99.4% of 517 | ≥80% support |
| GO | GO:0006884 Biological Process | cell volume homeostasis | 514 / 572 | 89.9% | 99.4% of 517 | ≥80% support |
| GO | GO:0035725 Biological Process | sodium ion transmembrane transport | 513 / 572 | 89.7% | 99.2% of 517 | ≥80% support |
| GO | GO:0055078 Biological Process | sodium ion homeostasis | 513 / 572 | 89.7% | 99.2% of 517 | ≥80% support |
| GO | GO:0008511 Molecular Function | sodium:potassium:chloride symporter activity | 513 / 572 | 89.7% | 99.2% of 517 | ≥80% support |
| GO | GO:0055085 Biological Process | transmembrane transport | 479 / 572 | 83.7% | 92.7% of 517 | ≥80% support |
| GO | GO:0022857 Molecular Function | transmembrane transporter activity | 477 / 572 | 83.4% | 92.3% of 517 | ≥80% support |
| KEGG | K10951 | SLC12A2, NKCC1 — Transporters | 376 / 572 | 65.7% | 97.7% of 385 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene11699.t1 | XP_020917454.1 | solute carrier family 12 member 2 [Exaiptasia diaphana] | P55012 Solute carrier family 12 member 2 OS=Mus musculus OX=10090 G | JBrowse |
| Actinoscyphia liui | gene12617.t1 | XP_020907442.1 | solute carrier family 12 member 1 [Exaiptasia diaphana] | P55011 Solute carrier family 12 member 2 OS=Homo sapiens OX=9606 GN | JBrowse |
