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This orthogroup contains 457 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 457 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| Pfam | PF00017 | SH2 | 381 / 457 | 83.4% | 92.9% of 410 | ≥80% support |
| GO | GO:0005515 Molecular Function | protein binding | 377 / 457 | 82.5% | 92.6% of 407 | ≥80% support |
| GO | GO:0007165 Biological Process | signal transduction | 368 / 457 | 80.5% | 90.4% of 407 | ≥80% support |
| PANTHER | PTHR46037 | PROTEIN ENHANCER OF SEVENLESS 2B | 350 / 457 | 76.6% | 86.2% of 406 | ≥50% support |
| Pfam | PF00018 | SH3_1 — SH3 domain | 360 / 457 | 78.8% | 87.8% of 410 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 352 / 457 | 77.0% | 86.5% of 407 | ≥50% support |
| GO | GO:0005886 Cellular Component | plasma membrane | 351 / 457 | 76.8% | 86.2% of 407 | ≥50% support |
| GO | GO:0001784 Molecular Function | phosphotyrosine residue binding | 350 / 457 | 76.6% | 86.0% of 407 | ≥50% support |
| GO | GO:0005154 Molecular Function | epidermal growth factor receptor binding | 350 / 457 | 76.6% | 86.0% of 407 | ≥50% support |
| GO | GO:0005654 Cellular Component | nucleoplasm | 350 / 457 | 76.6% | 86.0% of 407 | ≥50% support |
| GO | GO:0008180 Cellular Component | COP9 signalosome | 350 / 457 | 76.6% | 86.0% of 407 | ≥50% support |
| GO | GO:0043408 Biological Process | regulation of MAPK cascade | 350 / 457 | 76.6% | 86.0% of 407 | ≥50% support |
| KEGG | K04364 | GRB2 — Membrane trafficking | 263 / 457 | 57.6% | 98.5% of 267 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene00829.t1 | XP_020898464.2 | LOW QUALITY PROTEIN: tyrosine-protein kinase CSK-like [Exaiptasia diaphana] | P41239 Tyrosine-protein kinase CSK OS=Gallus gallus OX=9031 GN=CSK | JBrowse |
| Actinoscyphia liui | gene10263.t1 | XP_020901529.1 | growth factor receptor-bound protein 2 [Exaiptasia diaphana] | Q66II3 Growth factor receptor-bound protein 2 OS=Xenopus tropicalis | JBrowse |
