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This orthogroup contains 416 genes from 141 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 416 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11276 | DNA POLYMERASE TYPE-X FAMILY MEMBER | 362 / 416 | 87.0% | 99.2% of 365 | ≥80% support |
| GO | GO:0003677 Molecular Function | DNA binding | 367 / 416 | 88.2% | 100.0% of 367 | ≥80% support |
| GO | GO:0003887 Molecular Function | DNA-directed DNA polymerase activity | 365 / 416 | 87.7% | 99.5% of 367 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 365 / 416 | 87.7% | 99.5% of 367 | ≥80% support |
| GO | GO:0006303 Biological Process | double-strand break repair via nonhomologous end joining | 362 / 416 | 87.0% | 98.6% of 367 | ≥80% support |
| Pfam | PF14792 | DNA_pol_B_palm — DNA polymerase beta palm | 319 / 416 | 76.7% | 85.8% of 372 | ≥50% support |
| Pfam | PF14716 | HHH_8 — Helix-hairpin-helix domain | 306 / 416 | 73.6% | 82.3% of 372 | ≥50% support |
| Pfam | PF14791 | DNA_pol_B_thumb — DNA polymerase beta thumb | 304 / 416 | 73.1% | 81.7% of 372 | ≥50% support |
| Pfam | PF10391 | DNA_pol_lambd_f — Fingers domain of DNA polymerase lambda | 299 / 416 | 71.9% | 80.4% of 372 | ≥50% support |
| GO | GO:0034061 Molecular Function | DNA polymerase activity | 300 / 416 | 72.1% | 81.7% of 367 | ≥50% support |
| GO | GO:0016779 Molecular Function | nucleotidyltransferase activity | 283 / 416 | 68.0% | 77.1% of 367 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene18718.t1 | XP_020898152.1 | DNA polymerase lambda-like [Exaiptasia diaphana] | Q9UGP5 DNA polymerase lambda OS=Homo sapiens OX=9606 GN=POLL PE=1 S | JBrowse |
| Actinoscyphia liui | gene23926.t1 | XP_020895429.1 | DNA polymerase beta [Exaiptasia diaphana] | Q27958 DNA polymerase beta OS=Bos taurus OX=9913 GN=POLB PE=2 SV=3 | JBrowse |
