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This orthogroup contains 381 genes from 142 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 381 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR37402 | GRAM DOMAIN-CONTAINING PROTEIN 4 | 320 / 381 | 84.0% | 98.8% of 324 | ≥80% support |
| GO | GO:0006915 Biological Process | apoptotic process | 320 / 381 | 84.0% | 99.1% of 323 | ≥80% support |
| GO | GO:0034164 Biological Process | negative regulation of toll-like receptor 9 signaling pathway | 320 / 381 | 84.0% | 99.1% of 323 | ≥80% support |
| GO | GO:0043280 Biological Process | obsolete positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | 320 / 381 | 84.0% | 99.1% of 323 | ≥80% support |
| Pfam | PF02893 | GRAM | 267 / 381 | 70.1% | 96.4% of 277 | ≥50% support |
| KEGG | K23554 | GRAMD4 — Membrane trafficking | 219 / 381 | 57.5% | 98.7% of 222 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene25842.t1 | KXJ20627.1 | GRAM domain-containing protein 4 [Exaiptasia diaphana] | – | JBrowse |
| Actinoscyphia liui | gene25842.t2 | XP_031570548.1 | GRAM domain-containing protein 4-like [Actinia tenebrosa] | – | JBrowse |
| Actinoscyphia liui | gene25847.t1 | KXJ20627.1 | GRAM domain-containing protein 4 [Exaiptasia diaphana] | Q6IC98 GRAM domain-containing protein 4 OS=Homo sapiens OX=9606 GN= | JBrowse |