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This orthogroup contains 311 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 311 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR10887 | DNA2/NAM7 HELICASE FAMILY | 211 / 311 | 67.9% | 83.7% of 252 | ≥50% support |
| Pfam | PF08696 | Dna2 | 218 / 311 | 70.1% | 83.2% of 262 | ≥50% support |
| Pfam | PF13087 | AAA_12 — AAA domain | 207 / 311 | 66.6% | 79.0% of 262 | ≥50% support |
| Pfam | PF13086 | AAA_11 — AAA domain | 205 / 311 | 65.9% | 78.2% of 262 | ≥50% support |
| Pfam | PF21123 | Dna2_Rift — Dna2 Rift barrel domain | 173 / 311 | 55.6% | 66.0% of 262 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 211 / 311 | 67.9% | 95.5% of 221 | ≥50% support |
| GO | GO:0017108 Molecular Function | 5'-flap endonuclease activity | 211 / 311 | 67.9% | 95.5% of 221 | ≥50% support |
| GO | GO:0071932 Biological Process | replication fork reversal | 211 / 311 | 67.9% | 95.5% of 221 | ≥50% support |
| GO | GO:0004386 Molecular Function | helicase activity | 205 / 311 | 65.9% | 92.8% of 221 | ≥50% support |
| GO | GO:0017116 Molecular Function | single-stranded DNA helicase activity | 190 / 311 | 61.1% | 86.0% of 221 | ≥50% support |
| KEGG | K10742 | DNA2 — DNA replication proteins | 176 / 311 | 56.6% | 99.4% of 177 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene06176.t1 | KXJ18167.1 | DNA replication ATP-dependent helicase/nuclease DNA2 [Exaiptasia diaphana] | Q8QHA5 DNA replication ATP-dependent helicase/nuclease DNA2 OS=Xeno | JBrowse |
