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This orthogroup contains 302 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 302 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR11922 | GMP SYNTHASE-RELATED | 270 / 302 | 89.4% | 99.6% of 271 | ≥80% support |
| GO | GO:0003921 Molecular Function | GMP synthase activity | 270 / 302 | 89.4% | 99.6% of 271 | ≥80% support |
| GO | GO:0005829 Cellular Component | cytosol | 270 / 302 | 89.4% | 99.6% of 271 | ≥80% support |
| GO | GO:0006177 Biological Process | GMP biosynthetic process | 270 / 302 | 89.4% | 99.6% of 271 | ≥80% support |
| GO | GO:0005524 Molecular Function | ATP binding | 262 / 302 | 86.8% | 96.7% of 271 | ≥80% support |
| GO | GO:0003922 Molecular Function | GMP synthase (glutamine-hydrolyzing) activity | 248 / 302 | 82.1% | 91.5% of 271 | ≥80% support |
| Pfam | PF00117 | GATase — Glutamine amidotransferase class-I | 241 / 302 | 79.8% | 89.6% of 269 | ≥50% support |
| Pfam | PF00958 | GMP_synt_C — GMP synthase C terminal domain | 220 / 302 | 72.9% | 81.8% of 269 | ≥50% support |
| Pfam | PF02540 | NAD_synthase — NAD synthase | 183 / 302 | 60.6% | 68.0% of 269 | ≥50% support |
| GO | GO:0006164 Biological Process | purine nucleotide biosynthetic process | 222 / 302 | 73.5% | 81.9% of 271 | ≥50% support |
| KEGG | K01951 | guaA, GMPS — Peptidases and inhibitors | 195 / 302 | 64.6% | 96.1% of 203 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene00249.t1 | XP_031552012.1 | GMP synthase [glutamine-hydrolyzing]-like [Actinia tenebrosa] | P49915 GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 | JBrowse |
| Actinoscyphia liui | gene00330.t1 | XP_031552012.1 | GMP synthase [glutamine-hydrolyzing]-like [Actinia tenebrosa] | Q3THK7 GMP synthase [glutamine-hydrolyzing] OS=Mus musculus OX=1009 | JBrowse |