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This orthogroup contains 264 genes from 143 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 264 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR31057 | E3 UFM1-PROTEIN LIGASE 1 | 238 / 264 | 90.2% | 100.0% of 238 | ≥80% support |
| GO | GO:0061666 Molecular Function | UFM1 ligase activity | 239 / 264 | 90.5% | 100.0% of 239 | ≥80% support |
| GO | GO:0071569 Biological Process | protein ufmylation | 239 / 264 | 90.5% | 100.0% of 239 | ≥80% support |
| GO | GO:0005789 Cellular Component | endoplasmic reticulum membrane | 238 / 264 | 90.2% | 99.6% of 239 | ≥80% support |
| GO | GO:0032434 Biological Process | regulation of proteasomal ubiquitin-dependent protein catabolic process | 238 / 264 | 90.2% | 99.6% of 239 | ≥80% support |
| GO | GO:0034976 Biological Process | response to endoplasmic reticulum stress | 238 / 264 | 90.2% | 99.6% of 239 | ≥80% support |
| GO | GO:0071568 Molecular Function | UFM1 transferase activity | 238 / 264 | 90.2% | 99.6% of 239 | ≥80% support |
| GO | GO:1990592 Biological Process | protein K69-linked ufmylation | 238 / 264 | 90.2% | 99.6% of 239 | ≥80% support |
| Pfam | PF09743 | E3_UFM1_ligase — E3 UFM1-protein ligase 1 | 210 / 264 | 79.6% | 99.5% of 211 | ≥50% support |
| KEGG | K22755 | UFL1 — Ubiquitin system | 161 / 264 | 61.0% | 98.2% of 164 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Actinoscyphia liui | gene29220.t1 | XP_020902269.1 | LOW QUALITY PROTEIN: E3 UFM1-protein ligase 1 homolog [Exaiptasia diaphana] | A7S2N8 E3 UFM1-protein ligase 1 homolog OS=Nematostella vectensis O | JBrowse |
