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This orthogroup contains 5,191 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 5,191 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR24416 | TYROSINE-PROTEIN KINASE RECEPTOR | 3859 / 5,191 | 74.3% | 92.6% of 4,167 | ≥50% support |
| Pfam | PF07714 | PK_Tyr_Ser-Thr — Protein tyrosine and serine/threonine kinase | 3954 / 5,191 | 76.2% | 89.4% of 4,423 | ≥50% support |
| GO | GO:0006468 Biological Process | protein phosphorylation | 3987 / 5,191 | 76.8% | 89.7% of 4,444 | ≥50% support |
| GO | GO:0004672 Molecular Function | protein kinase activity | 3985 / 5,191 | 76.8% | 89.7% of 4,444 | ≥50% support |
| GO | GO:0043235 Cellular Component | receptor complex | 3839 / 5,191 | 74.0% | 86.4% of 4,444 | ≥50% support |
| GO | GO:0005887 Cellular Component | plasma membrane | 3837 / 5,191 | 73.9% | 86.3% of 4,444 | ≥50% support |
| GO | GO:0004714 Molecular Function | transmembrane receptor protein tyrosine kinase activity | 3833 / 5,191 | 73.8% | 86.3% of 4,444 | ≥50% support |
| GO | GO:0007169 Biological Process | cell surface receptor protein tyrosine kinase signaling pathway | 3833 / 5,191 | 73.8% | 86.3% of 4,444 | ≥50% support |
| GO | GO:0007275 Biological Process | multicellular organism development | 3833 / 5,191 | 73.8% | 86.3% of 4,444 | ≥50% support |
| GO | GO:0033674 Biological Process | positive regulation of kinase activity | 3833 / 5,191 | 73.8% | 86.3% of 4,444 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 3659 / 5,191 | 70.5% | 82.3% of 4,444 | ≥50% support |
| GO | GO:0004713 Molecular Function | protein tyrosine kinase activity | 3232 / 5,191 | 62.3% | 72.7% of 4,444 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0009.g75.t1 | XP_029207243.2 | uncharacterized protein LOC114970916 isoform X1 [Acropora millepora] | P36888 Receptor-type tyrosine-protein kinase FLT3 OS=Homo sapiens O | JBrowse |
| Acropora microphthalma | amic_s0017.g16.t1 | XP_029189833.2 | uncharacterized protein LOC114956784 [Acropora millepora] | P26619 Platelet-derived growth factor receptor alpha OS=Xenopus lae | JBrowse |
| Acropora microphthalma | amic_s0017.g16.t2 | XP_029189833.2 | uncharacterized protein LOC114956784 [Acropora millepora] | P26619 Platelet-derived growth factor receptor alpha OS=Xenopus lae | JBrowse |
| Acropora microphthalma | amic_s0017.g24.t1 | XP_029189849.2 | uncharacterized protein LOC114956799 [Acropora millepora] | P22182 Fibroblast growth factor receptor 1 OS=Xenopus laevis OX=835 | JBrowse |
| Acropora microphthalma | amic_s1697.g1.t1 | XP_029179653.2 | angiopoietin-1 receptor-like [Acropora millepora] | P07949 Proto-oncogene tyrosine-protein kinase receptor Ret OS=Homo | JBrowse |
