Gene Family

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🧬 OG0000221

This orthogroup contains 2,575 genes from 145 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.

no term is shared by every member — best support 90.7%

Consensus functional annotation

Support counts the member genes carrying the term. % of genes is that count over all 2,575 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.

Source Term Name / description Support % of genes % annotated Consistency
PfamPF00010HLH — Helix-loop-helix DNA-binding domain2335 / 2,57590.7%99.9%
of 2,337
≥80% support
GOGO:0046983
Molecular Function
protein dimerization activity2337 / 2,57590.8%100.0%
of 2,338
≥80% support
GOGO:0000981
Molecular Function
DNA-binding transcription factor activity, RNA polymerase II-specific2321 / 2,57590.1%99.3%
of 2,338
≥80% support
GOGO:0006357
Biological Process
regulation of transcription by RNA polymerase II2156 / 2,57583.7%92.2%
of 2,338
≥80% support
PANTHERPTHR23349BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST1851 / 2,57571.9%79.7%
of 2,324
≥50% support
GOGO:0000977
Molecular Function
RNA polymerase II transcription regulatory region sequence-specific DNA binding1851 / 2,57571.9%79.2%
of 2,338
≥50% support
GOGO:0032502
Biological Process
developmental process1851 / 2,57571.9%79.2%
of 2,338
≥50% support
📊 Total members in OG0000221: 16 (filtered to AMICR · show all species)
Show: genes per page

Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.

Species Gene ID Top NCBI-NR hit
(accession)
Top NCBI-NR hit description
(source organism)
Top UniProt hit
(Swiss-Prot)
Genome browser
Acropora microphthalmaamic_s0012.g65.t1XP_029195278.2heart- and neural crest derivatives-expressed protein 2-like [Acropora millepora]Q90690
Heart- and neural crest derivatives-expressed protein 2 OS=G
JBrowse
Acropora microphthalmaamic_s0012.g66.t1XP_029195234.1heart- and neural crest derivatives-expressed protein 2-like [Acropora millepora]P57102
Heart- and neural crest derivatives-expressed protein 2 OS=D
JBrowse
Acropora microphthalmaamic_s0015.g66.t1XP_020629341.1achaete-scute homolog 1b-like [Orbicella faveolata]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Acropora microphthalmaamic_s0015.g67.t1XP_015762597.1PREDICTED: achaete-scute homolog 3-like [Acropora digitifera]M0QWB7
Achaete-scute homolog 5 OS=Mus musculus OX=10090 GN=Ascl5 PE
JBrowse
Acropora microphthalmaamic_s0015.g69.t1XP_029200397.1achaete-scute homolog 1-like [Acropora millepora]Q06234
Achaete-scute homolog 1 OS=Xenopus laevis OX=8355 GN=ascl1 P
JBrowse
Acropora microphthalmaamic_s0015.g69.t2XP_029200397.1achaete-scute homolog 1-like [Acropora millepora]Q06234
Achaete-scute homolog 1 OS=Xenopus laevis OX=8355 GN=ascl1 P
JBrowse
Acropora microphthalmaamic_s0015.g72.t1XP_015762589.1PREDICTED: achaete-scute homolog 1a-like [Acropora digitifera]Q90259
Achaete-scute homolog 1a OS=Danio rerio OX=7955 GN=ascl1a PE
JBrowse
Acropora microphthalmaamic_s0145.g4.t1XP_029196085.2helix-loop-helix protein delilah-like [Acropora millepora]P59101
Basic helix-loop-helix transcription factor scleraxis OS=Gal
JBrowse
Acropora microphthalmaamic_s0216.g10.t1XP_015779354.1PREDICTED: pancreas transcription factor 1 subunit alpha-like [Acropora digitifera]Q7ZSX3
Pancreas transcription factor 1 subunit alpha OS=Danio rerio
JBrowse
Acropora microphthalmaamic_s0216.g8.t1XP_029193772.2mesoderm posterior protein 2-like [Acropora millepora]P79782
Transcription factor 15 OS=Gallus gallus OX=9031 GN=TCF15 PE
JBrowse
Acropora microphthalmaamic_s0278.g7.t1XP_029208961.1protein lyl-1-like [Acropora millepora]P27792
Protein lyl-1 OS=Mus musculus OX=10090 GN=Lyl1 PE=2 SV=2
JBrowse
Acropora microphthalmaamic_s0319.g14.t1XP_015770457.1PREDICTED: protein lin-32-like [Acropora digitifera]Q9W6C8
Neurogenic differentiation factor 2 OS=Danio rerio OX=7955 G
JBrowse
Acropora microphthalmaamic_s0319.g15.t1XP_015770458.1PREDICTED: protein atonal homolog 1-like isoform X1 [Acropora digitifera]Q96RJ6
Fer3-like protein OS=Homo sapiens OX=9606 GN=FERD3L PE=1 SV=
JBrowse
Acropora microphthalmaamic_s0319.g16.t1XP_015770452.1PREDICTED: neurogenin-3-like [Acropora digitifera]Q6QHK4
Factor in the germline alpha OS=Homo sapiens OX=9606 GN=FIGL
JBrowse
Acropora microphthalmaamic_s0319.g17.t1XP_015770453.1PREDICTED: twist-related protein-like [Acropora digitifera]P13903
Twist-related protein OS=Xenopus laevis OX=8355 GN=twist1 PE
JBrowse
Acropora microphthalmaamic_s0330.g3.t1XP_029208910.1protein atonal homolog 8-like [Acropora millepora]D2CLZ9
Transcription factor atoh8 OS=Danio rerio OX=7955 GN=atoh8 P
JBrowse
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