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This orthogroup contains 2,126 genes from 149 species. The functional annotation below is the consensus of the family's member genes — each term is reported with the number of member genes that carry it.
Support counts the member genes carrying the term. % of genes is that count over all 2,126 members — the strict reading of “the whole family agrees”. % annotated is the same count over only those members for which this database has a prediction of that type, which shows how uniform the evidence is where evidence exists.
| Source | Term | Name / description | Support | % of genes | % annotated | Consistency |
|---|---|---|---|---|---|---|
| PANTHER | PTHR13710 | DNA HELICASE RECQ FAMILY MEMBER | 1739 / 2,126 | 81.8% | 99.7% of 1,744 | ≥80% support |
| GO | GO:0043138 Molecular Function | 3'-5' DNA helicase activity | 1741 / 2,126 | 81.9% | 96.1% of 1,811 | ≥80% support |
| GO | GO:0006281 Biological Process | DNA repair | 1741 / 2,126 | 81.9% | 96.1% of 1,811 | ≥80% support |
| GO | GO:0006310 Biological Process | DNA recombination | 1701 / 2,126 | 80.0% | 93.9% of 1,811 | ≥80% support |
| Pfam | PF00270 | DEAD | 1372 / 2,126 | 64.5% | 76.4% of 1,796 | ≥50% support |
| Pfam | PF00271 | Helicase_C — Helicase conserved C-terminal domain | 1362 / 2,126 | 64.1% | 75.8% of 1,796 | ≥50% support |
| Pfam | PF16124 | RecQ_Zn_bind — RecQ zinc-binding | 1251 / 2,126 | 58.8% | 69.7% of 1,796 | ≥50% support |
| GO | GO:0005737 Cellular Component | cytoplasm | 1691 / 2,126 | 79.5% | 93.4% of 1,811 | ≥50% support |
| GO | GO:0005694 Cellular Component | chromosome | 1690 / 2,126 | 79.5% | 93.3% of 1,811 | ≥50% support |
| GO | GO:0009378 Molecular Function | four-way junction helicase activity | 1690 / 2,126 | 79.5% | 93.3% of 1,811 | ≥50% support |
| GO | GO:0032508 Biological Process | DNA duplex unwinding | 1690 / 2,126 | 79.5% | 93.3% of 1,811 | ≥50% support |
| GO | GO:0006268 Biological Process | DNA unwinding involved in DNA replication | 1535 / 2,126 | 72.2% | 84.8% of 1,811 | ≥50% support |
| GO | GO:0000724 Biological Process | double-strand break repair via homologous recombination | 1535 / 2,126 | 72.2% | 84.8% of 1,811 | ≥50% support |
| GO | GO:0003676 Molecular Function | nucleic acid binding | 1443 / 2,126 | 67.9% | 79.7% of 1,811 | ≥50% support |
| GO | GO:0005524 Molecular Function | ATP binding | 1372 / 2,126 | 64.5% | 75.8% of 1,811 | ≥50% support |
| GO | GO:0004386 Molecular Function | helicase activity | 1166 / 2,126 | 54.8% | 64.4% of 1,811 | ≥50% support |
| GO | GO:0005634 Cellular Component | nucleus | 1155 / 2,126 | 54.3% | 63.8% of 1,811 | ≥50% support |
Column guide: Top NCBI-NR hit and Top UniProt hit are the closest characterised sequences found by homology search — they are not identifiers of the CnidoSite gene itself. Where a species has no Swiss-Prot hit above threshold the UniProt column is shown as –. Click a gene ID for its full annotation page.
| Species | Gene ID | Top NCBI-NR hit (accession) |
Top NCBI-NR hit description (source organism) |
Top UniProt hit (Swiss-Prot) |
Genome browser |
|---|---|---|---|---|---|
| Acropora microphthalma | amic_s0054.g29.t1 | XP_044172914.1 | LOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase-like [Acropora millepora] | Q14191 Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN OS | JBrowse |
| Acropora microphthalma | amic_s0082.g70.t1 | XP_044175570.1 | ATP-dependent DNA helicase Q5-like isoform X2 [Acropora millepora] | D4ACP5 ATP-dependent DNA helicase Q5 OS=Rattus norvegicus OX=10116 | JBrowse |
| Acropora microphthalma | amic_s0082.g70.t2 | XP_015756318.1 | PREDICTED: uncharacterized protein LOC107335795 [Acropora digitifera] | – | JBrowse |
| Acropora microphthalma | amic_s0128.g90.t1 | XP_044183951.1 | LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q1-like [Acropora millepora] | A8WK63 Putative ATP-dependent DNA helicase Q1 OS=Caenorhabditis bri | JBrowse |
| Acropora microphthalma | amic_s0128.g91.t1 | XP_044183951.1 | LOW QUALITY PROTEIN: ATP-dependent DNA helicase Q1-like [Acropora millepora] | Q6AYJ1 ATP-dependent DNA helicase Q1 OS=Rattus norvegicus OX=10116 | JBrowse |
| Acropora microphthalma | amic_s0193.g21.t1 | XP_044179599.1 | probable ATP-dependent DNA helicase RecQ [Acropora millepora] | Q9DEY9 RecQ-like DNA helicase BLM OS=Xenopus laevis OX=8355 GN=blm | JBrowse |
| Acropora microphthalma | amic_s0228.g12.t1 | XP_044184444.1 | Bloom syndrome protein-like isoform X2 [Acropora millepora] | Q9DEY9 RecQ-like DNA helicase BLM OS=Xenopus laevis OX=8355 GN=blm | JBrowse |
| Acropora microphthalma | amic_s4159.g1.t1 | XP_044175568.1 | ATP-dependent DNA helicase Q5-like isoform X1 [Acropora millepora] | O94762 ATP-dependent DNA helicase Q5 OS=Homo sapiens OX=9606 GN=REC | JBrowse |
